CRCGN014_HEPG2_3H:J01 Gene Set
Genes
41 genes differentially expressed following the CRCGN014_HEPG2_3H:J01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
7.51751
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
7.05252
|
|
E2F2
|
E2F transcription factor 2
|
5.24941
|
|
TIMP2
|
TIMP metallopeptidase inhibitor 2
|
4.97487
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
4.93405
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.52738
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
4.45518
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
4.1504
|
|
EPHA3
|
EPH receptor A3
|
2.90009
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.85912
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.57127
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
2.54054
|
|
MEST
|
mesoderm specific transcript
|
2.52244
|
|
SMIM40
|
small integral membrane protein 40
|
2.45627
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.45509
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.35359
|
|
STIMATE
|
STIM activating enhancer
|
2.32542
|
|
MX1
|
MX dynamin-like GTPase 1
|
2.26921
|
|
DIRAS3
|
DIRAS family, GTP-binding RAS-like 3
|
2.22525
|
|
IFIT1
|
interferon-induced protein with tetratricopeptide repeats 1
|
2.21399
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.15522
|
|
PNPLA3
|
patatin-like phospholipase domain containing 3
|
2.12712
|
|
TUBB2B
|
tubulin, beta 2B class IIb
|
2.12522
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-7.57621
|
|
LAP3
|
leucine aminopeptidase 3
|
-5.3581
|
|
CCNB1
|
cyclin B1
|
-5.23344
|
|
ISOC1
|
isochorismatase domain containing 1
|
-4.98072
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.91551
|
|
LDHD
|
lactate dehydrogenase D
|
-4.82768
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-3.94512
|
|
NCK1
|
NCK adaptor protein 1
|
-3.89195
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.81188
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.51772
|
|
COG7
|
component of oligomeric golgi complex 7
|
-3.05554
|
|
TMED10
|
transmembrane emp24-like trafficking protein 10 (yeast)
|
-2.88229
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.88213
|
|
TBC1D31
|
TBC1 domain family, member 31
|
-2.87346
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.72831
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.70816
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.0953
|
|
C15ORF38-AP3S2
|
C15orf38-AP3S2 readthrough
|
-2.04179
|
