CRCGN014_HEPG2_3H:J09 Gene Set
Genes
49 genes differentially expressed following the CRCGN014_HEPG2_3H:J09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
4.19493
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.75042
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
3.65652
|
|
EPHB2
|
EPH receptor B2
|
3.40228
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
3.38698
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.31074
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
3.28334
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.00843
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
2.99697
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.96801
|
|
UBQLN2
|
ubiquilin 2
|
2.94178
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.86737
|
|
STIMATE
|
STIM activating enhancer
|
2.86694
|
|
CCDC92
|
coiled-coil domain containing 92
|
2.83209
|
|
VGLL4
|
vestigial-like family member 4
|
2.72828
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.70987
|
|
CHN1
|
chimerin 1
|
2.70024
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.66049
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.64364
|
|
ARID4B
|
AT rich interactive domain 4B (RBP1-like)
|
2.5674
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.40821
|
|
CSK
|
c-src tyrosine kinase
|
2.39483
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.35121
|
|
EPN2
|
epsin 2
|
2.29826
|
|
SORBS3
|
sorbin and SH3 domain containing 3
|
2.29347
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.23375
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
2.16124
|
|
CCDC86
|
coiled-coil domain containing 86
|
2.0886
|
|
RAP1GAP
|
RAP1 GTPase activating protein
|
2.07211
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.77233
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-6.19057
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.14907
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.78198
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.71493
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.47982
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.39459
|
|
ZNF586
|
zinc finger protein 586
|
-3.29108
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.0834
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.92726
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.89706
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.86854
|
|
WASHC4
|
WASH complex subunit 4
|
-2.7903
|
|
CCNB2
|
cyclin B2
|
-2.76172
|
|
CD320
|
CD320 molecule
|
-2.64303
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.57772
|
|
CCNB1
|
cyclin B1
|
-2.44852
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.26558
|
|
SNX11
|
sorting nexin 11
|
-2.18976
|
|
PDZD2
|
PDZ domain containing 2
|
-2.14171
|
