CRCGN014_HEPG2_3H:J11 Gene Set
Genes
37 genes differentially expressed following the CRCGN014_HEPG2_3H:J11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHMP6
|
charged multivesicular body protein 6
|
6.92681
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
6.71747
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
5.55983
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.29475
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
4.28451
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
4.25746
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.77174
|
|
MYLK
|
myosin light chain kinase
|
3.49718
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.91718
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.75796
|
|
HOXA10
|
homeobox A10
|
2.75366
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.67042
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.55251
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.5229
|
|
SAA2
|
serum amyloid A2
|
2.3907
|
|
SDHD
|
succinate dehydrogenase complex, subunit D, integral membrane protein
|
2.15404
|
|
TBXA2R
|
thromboxane A2 receptor
|
2.11713
|
|
RBKS
|
ribokinase
|
2.08179
|
|
GGT5
|
gamma-glutamyltransferase 5
|
2.05466
|
|
MRPS22
|
mitochondrial ribosomal protein S22
|
2.02587
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-8.42093
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.5448
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.79279
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-4.37865
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.15995
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.81774
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.65015
|
|
CDC20
|
cell division cycle 20
|
-3.53421
|
|
DNM1L
|
dynamin 1-like
|
-3.52125
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.42252
|
|
CSK
|
c-src tyrosine kinase
|
-3.06137
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.88178
|
|
SOAT2
|
sterol O-acyltransferase 2
|
-2.33031
|
|
DYNC1LI1
|
dynein, cytoplasmic 1, light intermediate chain 1
|
-2.15052
|
|
STN1
|
STN1 subunit of CST complex
|
-2.13617
|
|
SEC24C
|
SEC24 family member C
|
-2.08662
|
|
ELOVL4
|
ELOVL fatty acid elongase 4
|
-2.05633
|
