CRCGN014_HEPG2_3H:J12 Gene Set
Genes
49 genes differentially expressed following the CRCGN014_HEPG2_3H:J12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
5.3825
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.2357
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.12923
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.81167
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
3.59273
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.34972
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.29642
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.19621
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.81438
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.73081
|
|
KLHL9
|
kelch-like family member 9
|
2.67101
|
|
STIMATE
|
STIM activating enhancer
|
2.62777
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.58561
|
|
STAT3
|
signal transducer and activator of transcription 3 (acute-phase response factor)
|
2.43411
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.38622
|
|
RRAGA
|
Ras-related GTP binding A
|
2.37561
|
|
TEX10
|
testis expressed 10
|
2.31688
|
|
EGF
|
epidermal growth factor
|
2.13668
|
|
PPA2
|
pyrophosphatase (inorganic) 2
|
2.07984
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.06225
|
|
GATA3
|
GATA binding protein 3
|
2.05714
|
|
TTC27
|
tetratricopeptide repeat domain 27
|
2.01486
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-6.01293
|
|
CCNB2
|
cyclin B2
|
-5.9998
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.58896
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-5.51113
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-4.78001
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-4.44126
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.68694
|
|
ZNF586
|
zinc finger protein 586
|
-3.50216
|
|
VAT1
|
vesicle amine transport 1
|
-3.45204
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.41052
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.28439
|
|
CDC20
|
cell division cycle 20
|
-3.22369
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.98979
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.86463
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.84474
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.81941
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.73387
|
|
GNAS
|
GNAS complex locus
|
-2.54516
|
|
CDC25B
|
cell division cycle 25B
|
-2.43992
|
|
MXI1
|
MAX interactor 1, dimerization protein
|
-2.3249
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.27756
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.25494
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-2.23807
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.14181
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.1406
|
|
GOLGA6L9
|
golgin A6 family-like 9
|
-2.11277
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.00929
|
