| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1h-1,2,3-benzotriazole 20.99 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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62 genes differentially expressed following the CRCGN014_HEPG2_3H:J14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 7.14095 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.15028 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 4.0902 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.91692 |
| LCN2 | lipocalin 2 | 3.75557 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 3.6261 |
| CCDC92 | coiled-coil domain containing 92 | 3.59084 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.44466 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 3.43279 |
| SAA2 | serum amyloid A2 | 3.37055 |
| E2F2 | E2F transcription factor 2 | 3.32617 |
| LAGE3 | L antigen family, member 3 | 3.16844 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.0548 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.04004 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.01205 |
| MYLK | myosin light chain kinase | 2.84729 |
| STK10 | serine/threonine kinase 10 | 2.81357 |
| BAMBI | BMP and activin membrane-bound inhibitor | 2.79879 |
| CSK | c-src tyrosine kinase | 2.55935 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.28039 |
| NUP133 | nucleoporin 133kDa | 2.25063 |
| ABHD6 | abhydrolase domain containing 6 | 2.11019 |
| ENO2 | enolase 2 (gamma, neuronal) | 2.08664 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.06075 |
| RAP1GAP | RAP1 GTPase activating protein | 2.05062 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 2.0492 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 2.04682 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.073 |
| ZNF586 | zinc finger protein 586 | -5.29413 |
| ADI1 | acireductone dioxygenase 1 | -4.85571 |
| HMG20B | high mobility group 20B | -4.44851 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.27048 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -3.76623 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.70304 |
| TRIB3 | tribbles pseudokinase 3 | -3.31363 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.24109 |
| EIF5 | eukaryotic translation initiation factor 5 | -3.20096 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -3.15819 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -3.12438 |
| GNAS | GNAS complex locus | -2.87904 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.81096 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.79879 |
| PRPF4 | pre-mRNA processing factor 4 | -2.76088 |
| PCNA | proliferating cell nuclear antigen | -2.67505 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.66079 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.60892 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -2.60775 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.57517 |
| WASHC4 | WASH complex subunit 4 | -2.52307 |
| CHEK1 | checkpoint kinase 1 | -2.47412 |
| GHITM | growth hormone inducible transmembrane protein | -2.43097 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.42624 |
| METTL22 | methyltransferase like 22 | -2.25238 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.24923 |
| DNAJC13 | DnaJ (Hsp40) homolog, subfamily C, member 13 | -2.14875 |
| MARCHF5 | membrane associated ring-CH-type finger 5 | -2.14409 |
| SETD3 | SET domain containing 3 | -2.08055 |
| CASP8AP2 | caspase 8 associated protein 2 | -2.03711 |
| GOLT1A | golgi transport 1A | -2.03455 |
| RNF38 | ring finger protein 38 | -2.03174 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -2.00637 |
