CRCGN014_HEPG2_3H:J21 Gene Set
Genes
38 genes differentially expressed following the CRCGN014_HEPG2_3H:J21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CYCS
|
cytochrome c, somatic
|
4.86661
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
4.72677
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.52506
|
|
LCN2
|
lipocalin 2
|
3.60449
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.59815
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.49842
|
|
NOTCH1
|
notch 1
|
2.99114
|
|
CORO1A
|
coronin, actin binding protein, 1A
|
2.91816
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.75424
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.72961
|
|
EGF
|
epidermal growth factor
|
2.60228
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.43851
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.32007
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.29969
|
|
EVL
|
Enah/Vasp-like
|
2.26516
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.26435
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
2.23157
|
|
CHN1
|
chimerin 1
|
2.16079
|
|
MAP7
|
microtubule-associated protein 7
|
2.13927
|
|
ADGRA3
|
adhesion G protein-coupled receptor A3
|
2.08346
|
|
KIF20A
|
kinesin family member 20A
|
2.03774
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-6.23214
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.31385
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.764
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.45148
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.37727
|
|
LDHD
|
lactate dehydrogenase D
|
-3.33435
|
|
HMG20B
|
high mobility group 20B
|
-3.25826
|
|
LGMN
|
legumain
|
-3.06883
|
|
LYPLA1
|
lysophospholipase I
|
-2.94264
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.93988
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.93096
|
|
CRKL
|
v-crk avian sarcoma virus CT10 oncogene homolog-like
|
-2.91717
|
|
ERC2
|
ELKS/RAB6-interacting/CAST family member 2
|
-2.84808
|
|
TBC1D31
|
TBC1 domain family, member 31
|
-2.56975
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.43321
|
|
ATP6V1H
|
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
|
-2.21055
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.02129
|
