| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 9-ethyl-9h-carbazol-3-amine hydrochloride 40.0 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
55 genes differentially expressed following the CRCGN014_HEPG2_3H:J23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 8.11074 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 3.81701 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.6457 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 3.5146 |
| MYLK | myosin light chain kinase | 3.36724 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.29896 |
| DHDDS | dehydrodolichyl diphosphate synthase | 3.1986 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.94427 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.92774 |
| DIPK1A | divergent protein kinase domain 1A | 2.53745 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.53106 |
| MEST | mesoderm specific transcript | 2.52685 |
| EPHA3 | EPH receptor A3 | 2.51085 |
| SAA2 | serum amyloid A2 | 2.43647 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.33496 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 2.32434 |
| CCDC86 | coiled-coil domain containing 86 | 2.27439 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 2.24059 |
| CIDEA | cell death-inducing DFFA-like effector a | 2.23798 |
| MOBP | myelin-associated oligodendrocyte basic protein | 2.17864 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | 2.17005 |
| TFF1 | trefoil factor 1 | 2.15049 |
| FAM107A | family with sequence similarity 107, member A | 2.1474 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 2.10098 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.09356 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 2.0812 |
| C5 | complement component 5 | 2.05557 |
| NBPF19 | neuroblastoma breakpoint family, member 19 | 2.04392 |
| GAR1 | GAR1 ribonucleoprotein | 2.018 |
| BCL2 | B-cell CLL/lymphoma 2 | 2.01636 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | -5.34347 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -4.60673 |
| FASTKD5 | FAST kinase domains 5 | -4.35504 |
| TUBB6 | tubulin, beta 6 class V | -4.20296 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -3.80966 |
| CDC20 | cell division cycle 20 | -3.74585 |
| SCAND1 | SCAN domain containing 1 | -3.09903 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.08998 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.06641 |
| NGRN | neugrin, neurite outgrowth associated | -2.98189 |
| LYPLA1 | lysophospholipase I | -2.71643 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.70642 |
| WASHC4 | WASH complex subunit 4 | -2.5127 |
| SNX11 | sorting nexin 11 | -2.49113 |
| TLCD3A | TLC domain containing 3A | -2.48616 |
| PARP2 | poly (ADP-ribose) polymerase 2 | -2.43787 |
| CCNB1 | cyclin B1 | -2.26603 |
| C1QL1 | complement component 1, q subcomponent-like 1 | -2.19726 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.12837 |
| SMNDC1 | survival motor neuron domain containing 1 | -2.12692 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase | -2.1185 |
| DCP2 | decapping mRNA 2 | -2.11704 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -2.10549 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -2.10263 |
| CCNB2 | cyclin B2 | -2.08119 |
