| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | methyl methacrylate 39.0 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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63 genes differentially expressed following the CRCGN014_HEPG2_3H:K03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CBR3 | carbonyl reductase 3 | 5.35178 |
| ADRB2 | adrenoceptor beta 2, surface | 5.2774 |
| BZW2 | basic leucine zipper and W2 domains 2 | 4.92836 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.705 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.66571 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.50105 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 4.40381 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.33556 |
| CYCS | cytochrome c, somatic | 4.26938 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.64685 |
| JADE2 | jade family PHD finger 2 | 3.47738 |
| KIF20A | kinesin family member 20A | 3.40987 |
| PNKP | polynucleotide kinase 3'-phosphatase | 3.37795 |
| PLSCR3 | phospholipid scramblase 3 | 3.36588 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 3.15324 |
| EVL | Enah/Vasp-like | 3.12549 |
| GATA2 | GATA binding protein 2 | 2.83861 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 2.81807 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 2.7584 |
| PCDHB11 | protocadherin beta 11 | 2.75561 |
| CDK19 | cyclin-dependent kinase 19 | 2.55631 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 2.53149 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 2.53014 |
| TAC4 | tachykinin 4 (hemokinin) | 2.48931 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 2.2401 |
| PFAS | phosphoribosylformylglycinamidine synthase | 2.14835 |
| PCOLCE | procollagen C-endopeptidase enhancer | 2.12821 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.10025 |
| NOSIP | nitric oxide synthase interacting protein | 2.03828 |
| COX8A | cytochrome c oxidase subunit VIIIA (ubiquitous) | 2.03236 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -8.45454 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -7.65422 |
| DNM1L | dynamin 1-like | -4.89797 |
| MPC2 | mitochondrial pyruvate carrier 2 | -4.6871 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -4.63148 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -4.38451 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.19443 |
| CTSD | cathepsin D | -3.95743 |
| TLR4 | toll-like receptor 4 | -3.89116 |
| ZNF586 | zinc finger protein 586 | -3.76984 |
| RGS2 | regulator of G-protein signaling 2 | -3.57701 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -3.1455 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | -3.06566 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -3.05053 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -2.74807 |
| TLCD3A | TLC domain containing 3A | -2.62433 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | -2.54009 |
| TES | testin LIM domain protein | -2.51413 |
| TBC1D31 | TBC1 domain family, member 31 | -2.45448 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.40834 |
| SYNPO2 | synaptopodin 2 | -2.26923 |
| PRSS22 | protease, serine, 22 | -2.22995 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -2.18198 |
| CCNH | cyclin H | -2.17585 |
| MVD | mevalonate (diphospho) decarboxylase | -2.15647 |
| RAI14 | retinoic acid induced 14 | -2.12379 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -2.09062 |
| LYZL6 | lysozyme-like 6 | -2.04576 |
| EPB42 | erythrocyte membrane protein band 4.2 | -2.0342 |
| E4F1 | E4F transcription factor 1 | -2.02701 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides | -2.00932 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -2.00429 |
| GRB7 | growth factor receptor-bound protein 7 | -2.00327 |
