CRCGN014_HEPG2_3H:K04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description hc yellow 4 40.0 um perturbation at 3 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

97 genes differentially expressed following the CRCGN014_HEPG2_3H:K04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 7.79416
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 6.28838
GPER1 G protein-coupled estrogen receptor 1 5.80946
NR1H2 nuclear receptor subfamily 1, group H, member 2 4.98846
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.67577
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 3.07986
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.69183
C2CD2 C2 calcium-dependent domain containing 2 2.54999
GPATCH8 G patch domain containing 8 2.52597
CCNF cyclin F 2.51316
TPD52L2 tumor protein D52-like 2 2.40387
CXCL2 chemokine (C-X-C motif) ligand 2 2.29629
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 2.20488
INTS8 integrator complex subunit 8 2.17654
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 2.14323
NOSIP nitric oxide synthase interacting protein 2.11994
TIGAR TP53 induced glycolysis regulatory phosphatase 2.08343
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 2.03318
TEX10 testis expressed 10 2.03097
NOL8 nucleolar protein 8 2.01974
GID8 GID complex subunit 8 2.00901

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -7.99118
ZNF586 zinc finger protein 586 -7.96384
CDC20 cell division cycle 20 -7.17363
GNAS GNAS complex locus -6.02854
PEG10 paternally expressed 10 -5.42723
TLR4 toll-like receptor 4 -3.93583
MAPK13 mitogen-activated protein kinase 13 -3.51642
VAT1 vesicle amine transport 1 -2.81697
EGF epidermal growth factor -2.73093
ZNF141 zinc finger protein 141 -2.65792
SLC6A16 solute carrier family 6, member 16 -2.6499
ZNF132 zinc finger protein 132 -2.57113
ZFY zinc finger protein, Y-linked -2.55333
ZNF345 zinc finger protein 345 -2.52905
PLAAT1 phospholipase A and acyltransferase 1 -2.48588
RAB30 RAB30, member RAS oncogene family -2.44427
ZNF471 zinc finger protein 471 -2.3966
ZNF780A zinc finger protein 780A -2.3868
KPNA5 karyopherin alpha 5 (importin alpha 6) -2.38201
ZNF287 zinc finger protein 287 -2.35688
WDR7 WD repeat domain 7 -2.33472
ZNF10 zinc finger protein 10 -2.32836
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.28985
SLC30A4 solute carrier family 30 (zinc transporter), member 4 -2.27894
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 -2.25487
PEX5L peroxisomal biogenesis factor 5-like -2.24302
UBQLN3 ubiquilin 3 -2.23024
ZNF675 zinc finger protein 675 -2.2172
LATS1 large tumor suppressor kinase 1 -2.21035
PCDHB8 protocadherin beta 8 -2.19642
PCDHGA1 protocadherin gamma subfamily A, 1 -2.19066
ZKSCAN8 zinc finger with KRAB and SCAN domains 8 -2.1896
ZNF550 zinc finger protein 550 -2.1806
DOCK1 dedicator of cytokinesis 1 -2.15217
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E -2.15208
PACS1 phosphofurin acidic cluster sorting protein 1 -2.15099
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 -2.14945
ZNF85 zinc finger protein 85 -2.14801
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28 -2.14453
SCN2A sodium channel, voltage gated, type II alpha subunit -2.14234
STXBP5L syntaxin binding protein 5-like -2.14027
CCDC121 coiled-coil domain containing 121 -2.13322
NEUROD4 neuronal differentiation 4 -2.12596
KMT2D lysine (K)-specific methyltransferase 2D -2.1242
ST14 suppression of tumorigenicity 14 (colon carcinoma) -2.11923
ZNF460 zinc finger protein 460 -2.11074
CEP97 centrosomal protein 97kDa -2.11055
ERV3-1-ZNF117 ERV3-1-ZNF117 readthrough -2.11042
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 -2.09488
PLA2R1 phospholipase A2 receptor 1, 180kDa -2.07904
PLCL1 phospholipase C-like 1 -2.06402
ZFP69B ZFP69 zinc finger protein B -2.05965
ZNF549 zinc finger protein 549 -2.055
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa -2.04915
ZNF155 zinc finger protein 155 -2.04718
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial -2.04093
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 -2.03917
ZNF254 zinc finger protein 254 -2.0313
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) -2.02703
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 -2.02611
TSBP1 testis expressed basic protein 1 -2.02264
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 -2.02212
SIM1 single-minded family bHLH transcription factor 1 -2.02024
OR10J1 olfactory receptor, family 10, subfamily J, member 1 -2.01873
ZNF253 zinc finger protein 253 -2.01566
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 -2.01455
PEDS1 plasmanylethanolamine desaturase 1 -2.01365
MAGEB4 melanoma antigen family B4 -2.01336
PTGFR prostaglandin F receptor (FP) -2.01026
CCDC86 coiled-coil domain containing 86 -2.00904
PDE12 phosphodiesterase 12 -2.00892
BMP10 bone morphogenetic protein 10 -2.00802
ZFP2 ZFP2 zinc finger protein -2.00764
ZNF544 zinc finger protein 544 -2.00225
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 -2.00067
PTPRK protein tyrosine phosphatase, receptor type, K -2.00048