CRCGN014_HEPG2_3H:K07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acetamide 41.6 um perturbation at 3 h in HEPG2 (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN014_HEPG2_3H:K07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GPATCH8 G patch domain containing 8 4.52784
CARMIL1 capping protein regulator and myosin 1 linker 1 3.98535
DENND2D DENN/MADD domain containing 2D 3.60282
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.43012
JADE2 jade family PHD finger 2 3.37473
ABHD6 abhydrolase domain containing 6 3.03026
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.01174
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 2.74289
NOSIP nitric oxide synthase interacting protein 2.6981
KIF5C kinesin family member 5C 2.41145
RPP38 ribonuclease P/MRP 38kDa subunit 2.31205
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.14164

decreased expression

Symbol Name Standardized Value
CCNB2 cyclin B2 -9.53028
ZNF586 zinc finger protein 586 -3.90529
NGRN neugrin, neurite outgrowth associated -3.45044
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -3.37138
NT5DC2 5'-nucleotidase domain containing 2 -3.34693
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -3.31422
TUBB6 tubulin, beta 6 class V -3.30602
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.23654
OXA1L oxidase (cytochrome c) assembly 1-like -3.06856
CSK c-src tyrosine kinase -2.61114
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.56078
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.50613
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.26989
HSPA8 heat shock 70kDa protein 8 -2.26624
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.24339
PCNA proliferating cell nuclear antigen -2.20539
CASP7 caspase 7, apoptosis-related cysteine peptidase -2.12182
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.12137
TXNDC9 thioredoxin domain containing 9 -2.09411