| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | isopropyl-n-(3-chloro?phenyl)carbamate 39.6 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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91 genes differentially expressed following the CRCGN014_HEPG2_3H:K10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 8.79078 |
| CHMP6 | charged multivesicular body protein 6 | 7.75815 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 6.77481 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.3838 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.36453 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.96558 |
| PRKCD | protein kinase C, delta | 4.61674 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.55461 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.48881 |
| NOTCH1 | notch 1 | 3.62188 |
| BZW2 | basic leucine zipper and W2 domains 2 | 3.5502 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.20877 |
| SKIC2 | SKI2 subunit of superkiller complex | 3.18227 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.11834 |
| KIF5C | kinesin family member 5C | 3.10313 |
| HOXA10 | homeobox A10 | 3.07543 |
| SKIC8 | SKI8 subunit of superkiller complex | 3.04374 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 2.93856 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 2.93708 |
| GPATCH8 | G patch domain containing 8 | 2.912 |
| MAP7 | microtubule-associated protein 7 | 2.75085 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.68585 |
| CTSZ | cathepsin Z | 2.52839 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 2.50288 |
| CEP57 | centrosomal protein 57kDa | 2.49723 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | 2.47078 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 2.39773 |
| EVL | Enah/Vasp-like | 2.38944 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | 2.33551 |
| GPR143 | G protein-coupled receptor 143 | 2.30669 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.29541 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 2.27385 |
| SLC35B1 | solute carrier family 35, member B1 | 2.24607 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 2.24102 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 2.23897 |
| MAGEH1 | melanoma antigen family H1 | 2.18395 |
| GTPBP6 | GTP binding protein 6 (putative) | 2.17424 |
| STX18 | syntaxin 18 | 2.16868 |
| GARS1 | glycyl-tRNA synthetase 1 | 2.16092 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.07554 |
| G6PC3 | glucose 6 phosphatase, catalytic, 3 | 2.05144 |
| NDFIP1 | Nedd4 family interacting protein 1 | 2.03996 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 2.03959 |
| EEIG1 | estrogen-induced osteoclastogenesis regulator 1 | 2.02028 |
| TMPRSS11E | transmembrane protease, serine 11E | 2.0093 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -8.58158 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -8.15269 |
| ADI1 | acireductone dioxygenase 1 | -5.606 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -5.03514 |
| UBE3C | ubiquitin protein ligase E3C | -4.84707 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.72608 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.43037 |
| SCAND1 | SCAN domain containing 1 | -4.40833 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -4.40146 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.20618 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.8642 |
| TLR4 | toll-like receptor 4 | -3.61595 |
| YME1L1 | YME1-like 1 ATPase | -3.46467 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.46442 |
| CD58 | CD58 molecule | -3.40261 |
| TRIB3 | tribbles pseudokinase 3 | -3.32186 |
| EGF | epidermal growth factor | -2.45519 |
| PXMP4 | peroxisomal membrane protein 4, 24kDa | -2.4219 |
| FAM204A | family with sequence similarity 204, member A | -2.42102 |
| CCNB1 | cyclin B1 | -2.39411 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.37529 |
| IDH3B | isocitrate dehydrogenase 3 (NAD+) beta | -2.34194 |
| SERPINB7 | serpin peptidase inhibitor, clade B (ovalbumin), member 7 | -2.33716 |
| CRNKL1 | crooked neck pre-mRNA splicing factor 1 | -2.29968 |
| CYBRD1 | cytochrome b reductase 1 | -2.26696 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -2.21064 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 | -2.2061 |
| ADGRB2 | adhesion G protein-coupled receptor B2 | -2.18102 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -2.17052 |
| CDC73 | cell division cycle 73 | -2.13848 |
| MOB1A | MOB kinase activator 1A | -2.12676 |
| AURKB | aurora kinase B | -2.10316 |
| NHLRC2 | NHL repeat containing 2 | -2.08565 |
| MEST | mesoderm specific transcript | -2.08142 |
| CENPB | centromere protein B, 80kDa | -2.07953 |
| BDNF | brain-derived neurotrophic factor | -2.07734 |
| MACF1 | microtubule-actin crosslinking factor 1 | -2.06164 |
| DPF3 | D4, zinc and double PHD fingers, family 3 | -2.04518 |
| RYR2 | ryanodine receptor 2 (cardiac) | -2.04372 |
| KIAA0319 | KIAA0319 | -2.03466 |
| RSF1 | remodeling and spacing factor 1 | -2.02194 |
| APMAP | adipocyte plasma membrane associated protein | -2.01777 |
| ACSM1 | acyl-CoA synthetase medium-chain family member 1 | -2.01177 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -2.01165 |
| FILIP1L | filamin A interacting protein 1-like | -2.01079 |
| APOL3 | apolipoprotein L, 3 | -2.00659 |
