CRCGN014_HEPG2_3H:K13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description clofibrate 21.73 um perturbation at 3 h in HEPG2 (Carcinogenome)
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Genes

432 genes differentially expressed following the CRCGN014_HEPG2_3H:K13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 10.0
CSK c-src tyrosine kinase 10.0
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 10.0
STAP2 signal transducing adaptor family member 2 10.0
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 10.0
CBR3 carbonyl reductase 3 10.0
LOC122526780 uncharacterized LOC122526780 8.184
COL4A1 collagen, type IV, alpha 1 7.808
KCNK1 potassium channel, two pore domain subfamily K, member 1 7.6177
SATB1 SATB homeobox 1 6.9455
TIAM1 T-cell lymphoma invasion and metastasis 1 6.6896
COL4A2 collagen, type IV, alpha 2 5.9014
CEMIP2 cell migration inducing hyaluronidase 2 5.3347
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 5.1917
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 4.8712
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 4.3611
PLSCR3 phospholipid scramblase 3 3.8228
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 3.4164
OXCT1 3-oxoacid CoA transferase 1 3.3485
MAB21L4 mab-21 like 4 3.3429
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 3.32097
BZW2 basic leucine zipper and W2 domains 2 3.2218
CYBA cytochrome b-245, alpha polypeptide 3.1995
SPRR1A small proline-rich protein 1A 3.18565
ISG15 ISG15 ubiquitin-like modifier 3.1693
TRIB3 tribbles pseudokinase 3 3.1652
SCAND1 SCAN domain containing 1 3.1504
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 3.1405
CD1C CD1c molecule 3.1182
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 3.0921
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 3.0863
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 3.0657
GCHFR GTP cyclohydrolase I feedback regulator 3.0371
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 3.0203
SPRR2B small proline-rich protein 2B 3.0139
S100A2 S100 calcium binding protein A2 3.0101
MX1 MX dynamin-like GTPase 1 2.9813
FAM110A family with sequence similarity 110, member A 2.9584
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 2.9319
RAI14 retinoic acid induced 14 2.9033
NECAP2 NECAP endocytosis associated 2 2.8817
SPRR1B small proline-rich protein 1B 2.8516
RFC5 replication factor C (activator 1) 5, 36.5kDa 2.8254
GPR87 G protein-coupled receptor 87 2.8175
TMEM40 transmembrane protein 40 2.8091
HOOK2 hook microtubule-tethering protein 2 2.7798
ISCU iron-sulfur cluster assembly enzyme 2.7681
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.752
POMK protein-O-mannose kinase 2.73465
GATA2 GATA binding protein 2 2.7315
MRPS33 mitochondrial ribosomal protein S33 2.7175
CETN3 centrin, EF-hand protein, 3 2.7141
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 2.7031
TTBK2 tau tubulin kinase 2 2.6956
CSTB cystatin B (stefin B) 2.6954
MYD88 myeloid differentiation primary response 88 2.69
DOLPP1 dolichyldiphosphatase 1 2.686
CD83 CD83 molecule 2.6706
UPK3A uroplakin 3A 2.6701
PABPC3 poly(A) binding protein, cytoplasmic 3 2.664
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.65515
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 2.6527
PLCD1 phospholipase C, delta 1 2.6511
TMEM51 transmembrane protein 51 2.6395
TRAM2 translocation associated membrane protein 2 2.63475
ANXA8L1 annexin A8-like 1 2.6343
TPD52L2 tumor protein D52-like 2 2.6256
SYNGR3 synaptogyrin 3 2.6197
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 2.6189
DYNLL1 dynein, light chain, LC8-type 1 2.6158
NTM neurotrimin 2.6154
COG2 component of oligomeric golgi complex 2 2.6052
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 2.6015
SF3B2 splicing factor 3b, subunit 2, 145kDa 2.5913
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 2.59095
PGM1 phosphoglucomutase 1 2.582
HAPLN1 hyaluronan and proteoglycan link protein 1 2.5806
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 2.55965
RPL36AL ribosomal protein L36a-like 2.5456
PLAT plasminogen activator, tissue 2.5386
USP21 ubiquitin specific peptidase 21 2.5368
TDP1 tyrosyl-DNA phosphodiesterase 1 2.5315
GRN granulin 2.51843
ING3 inhibitor of growth family, member 3 2.51835
DONSON downstream neighbor of SON 2.5153
RPL39L ribosomal protein L39-like 2.5082
LARP7 La ribonucleoprotein domain family, member 7 2.4975
STRADA STE20-related kinase adaptor alpha 2.4921
KRT13 keratin 13, type I 2.488
ERCC5 excision repair cross-complementation group 5 2.4864
HMGN1 high mobility group nucleosome binding domain 1 2.4838
DKK1 dickkopf WNT signaling pathway inhibitor 1 2.4767
LTA4H leukotriene A4 hydrolase 2.4752
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 2.4727
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 2.45743
MIS18A MIS18 kinetochore protein A 2.456
RLIM ring finger protein, LIM domain interacting 2.4466
TCERG1 transcription elongation regulator 1 2.437
PITPNB phosphatidylinositol transfer protein, beta 2.4366
ENAH enabled homolog (Drosophila) 2.4302
HOXC11 homeobox C11 2.4264
PEAK1 pseudopodium-enriched atypical kinase 1 2.4089
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 2.4062
TEX10 testis expressed 10 2.3997
ANO10 anoctamin 10 2.3984
SPRR3 small proline-rich protein 3 2.3937
ZNF365 zinc finger protein 365 2.3824
RNPS1 RNA binding protein S1, serine-rich domain 2.37665
ALOX15 arachidonate 15-lipoxygenase 2.3618
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 2.3605
LUC7L2 LUC7-like 2 (S. cerevisiae) 2.35715
FGFBP1 fibroblast growth factor binding protein 1 2.354
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 2.3486
ADAMTSL4 ADAMTS-like 4 2.3467
GJB5 gap junction protein, beta 5, 31.1kDa 2.3403
VSTM4 V-set and transmembrane domain containing 4 2.3401
NTF3 neurotrophin 3 2.3332
DAAM1 dishevelled associated activator of morphogenesis 1 2.3288
FSTL1 follistatin-like 1 2.3259
H2AZ2 H2A.Z variant histone 2 2.31957
SPINK5 serine peptidase inhibitor, Kazal type 5 2.3158
KLHL9 kelch-like family member 9 2.3151
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 2.3135
LBHD1 LBH domain containing 1 2.3126
INTS14 integrator complex subunit 14 2.3113
CCKBR cholecystokinin B receptor 2.3109
CRNN cornulin 2.3025
RPL35 ribosomal protein L35 2.2983
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 2.2976
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 2.2877
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.2644
MKRN2 makorin ring finger protein 2 2.2635
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 2.263
CCT8 chaperonin containing TCP1, subunit 8 (theta) 2.2584
DENR density-regulated protein 2.2557
EPHX3 epoxide hydrolase 3 2.2541
ICAM1 intercellular adhesion molecule 1 2.25113
ADGRF1 adhesion G protein-coupled receptor F1 2.2493
ATL2 atlastin GTPase 2 2.2463
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.2407
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 2.2396
ZFPM2 zinc finger protein, FOG family member 2 2.2334
WWC2 WW and C2 domain containing 2 2.2274
TBX3 T-box 3 2.2271
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 2.2269
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 2.2259
IFI44L interferon-induced protein 44-like 2.2243
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 2.2233
MAPK10 mitogen-activated protein kinase 10 2.2195
CANT1 calcium activated nucleotidase 1 2.21765
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 2.2173
SKIC2 SKI2 subunit of superkiller complex 2.2139
COL15A1 collagen, type XV, alpha 1 2.2128
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 2.2128
NEMF nuclear export mediator factor 2.2114
RPL27A ribosomal protein L27a 2.206
IL17RB interleukin 17 receptor B 2.2051
MOGAT1 monoacylglycerol O-acyltransferase 1 2.2027
ATP5MJ ATP synthase membrane subunit j 2.1971
UFL1 UFM1-specific ligase 1 2.19675
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 2.1916
LRRC47 leucine rich repeat containing 47 2.1867
EDF1 endothelial differentiation-related factor 1 2.18455
CD5 CD5 molecule 2.1759
TRMO tRNA methyltransferase O 2.172
LYPD3 LY6/PLAUR domain containing 3 2.1712
GATA4 GATA binding protein 4 2.1686
RPL8 ribosomal protein L8 2.1602
MLYCD malonyl-CoA decarboxylase 2.16
THYN1 thymocyte nuclear protein 1 2.1593
H2AZ1 H2A.Z variant histone 1 2.15925
TP53 tumor protein p53 2.1591
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 2.1509
HMGB2 high mobility group box 2 2.1507
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 2.1476
PEX12 peroxisomal biogenesis factor 12 2.1466
PHKA2 phosphorylase kinase, alpha 2 (liver) 2.14635
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 2.1411
ANO1 anoctamin 1, calcium activated chloride channel 2.1402
LY6D lymphocyte antigen 6 complex, locus D 2.1343
TESK2 testis-specific kinase 2 2.1327
RNF34 ring finger protein 34, E3 ubiquitin protein ligase 2.1324
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 2.12985
TLK2 tousled-like kinase 2 2.12575
NEUROD6 neuronal differentiation 6 2.1228
ULBP2 UL16 binding protein 2 2.1175
ACOX1 acyl-CoA oxidase 1, palmitoyl 2.1167
CD40LG CD40 ligand 2.1112
PEG3 paternally expressed 3 2.10675
MGST2 microsomal glutathione S-transferase 2 2.1064
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 2.104
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 2.1016
DENND5B DENN/MADD domain containing 5B 2.097
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.0957
ATXN1 ataxin 1 2.08445
GID8 GID complex subunit 8 2.0792
CAVIN3 caveolae associated protein 3 2.0788
GSTZ1 glutathione S-transferase zeta 1 2.0728
JMJD4 jumonji domain containing 4 2.0707
LOC124900388 uncharacterized LOC124900388 2.0688
RAB25 RAB25, member RAS oncogene family 2.067
RAB11FIP1 RAB11 family interacting protein 1 (class I) 2.0657
ATP7B ATPase, Cu++ transporting, beta polypeptide 2.0606
IFI30 interferon, gamma-inducible protein 30 2.0596
RPS13 ribosomal protein S13 2.0577
NR1D2 nuclear receptor subfamily 1, group D, member 2 2.0475
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa 2.0465
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.0413
SPPL2A signal peptide peptidase like 2A 2.039
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 2.03843
ACTA2 actin, alpha 2, smooth muscle, aorta 2.0381
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1 2.0336
IVL involucrin 2.0313
SIRT7 sirtuin 7 2.0296
ELL3 elongation factor RNA polymerase II-like 3 2.0249
CCDC59 coiled-coil domain containing 59 2.0222
SCD5 stearoyl-CoA desaturase 5 2.0212
AP1G2 adaptor-related protein complex 1, gamma 2 subunit 2.0201
CRELD1 cysteine-rich with EGF-like domains 1 2.0193
KDM2A lysine (K)-specific demethylase 2A 2.01877
RPL34 ribosomal protein L34 2.016
ZIM2 zinc finger, imprinted 2 2.0157
CFAP298 cilia and flagella associated protein 298 2.0149
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.0109
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 2.0034

decreased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 -10.0
TARBP1 TAR (HIV-1) RNA binding protein 1 -10.0
CASP7 caspase 7, apoptosis-related cysteine peptidase -10.0
CD320 CD320 molecule -10.0
DERA deoxyribose-phosphate aldolase (putative) -9.5482
DUSP6 dual specificity phosphatase 6 -7.9021
CDC25B cell division cycle 25B -7.1695
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -6.5524
ZNF586 zinc finger protein 586 -6.1852
AZGP1 alpha-2-glycoprotein 1, zinc-binding -5.9207
GTPBP8 GTP-binding protein 8 (putative) -5.2
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -4.8634
GRWD1 glutamate-rich WD repeat containing 1 -4.2063
ITGB1BP1 integrin beta 1 binding protein 1 -4.1726
SYNE2 spectrin repeat containing, nuclear envelope 2 -4.1469
BRCA1 breast cancer 1, early onset -4.07455
TCEAL4 transcription elongation factor A (SII)-like 4 -3.97
RGS2 regulator of G-protein signaling 2 -3.9447
KIF13B kinesin family member 13B -3.6019
ITFG1 integrin alpha FG-GAP repeat containing 1 -3.5493
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.5458
RPIA ribose 5-phosphate isomerase A -3.3886
PAEP progestagen-associated endometrial protein -3.2852
NT5DC2 5'-nucleotidase domain containing 2 -3.2374
PRAF2 PRA1 domain family, member 2 -3.2265
TMEM14A transmembrane protein 14A -3.2056
MVP major vault protein -3.1651
CRYZ crystallin, zeta (quinone reductase) -3.118
HOXB5 homeobox B5 -3.04165
TMEM131 transmembrane protein 131 -3.033
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -2.9556
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -2.94545
QTRT1 queuine tRNA-ribosyltransferase 1 -2.9409
CYB5RL cytochrome b5 reductase-like -2.9074
JAG2 jagged 2 -2.87885
DBF4B DBF4 zinc finger B -2.8775
CASP5 caspase 5, apoptosis-related cysteine peptidase -2.8517
ECH1 enoyl CoA hydratase 1, peroxisomal -2.84
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.8256
FFAR2 free fatty acid receptor 2 -2.8151
IL18RAP interleukin 18 receptor accessory protein -2.7942
TXNDC9 thioredoxin domain containing 9 -2.7754
ZFP36L2 ZFP36 ring finger protein-like 2 -2.7628
PRMT7 protein arginine methyltransferase 7 -2.7441
ACLY ATP citrate lyase -2.69903
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) -2.6757
GC group-specific component (vitamin D binding protein) -2.6724
PRCC papillary renal cell carcinoma (translocation-associated) -2.6712
MCTP1 multiple C2 domains, transmembrane 1 -2.6703
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) -2.6514
CD300A CD300a molecule -2.637
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 -2.6245
BLMH bleomycin hydrolase -2.62
CLU clusterin -2.59967
CLEC16A C-type lectin domain family 16, member A -2.5991
CST5 cystatin D -2.594
ANO3 anoctamin 3 -2.576
DYNLT3 dynein, light chain, Tctex-type 3 -2.5666
SLAMF7 SLAM family member 7 -2.5638
MED22 mediator complex subunit 22 -2.5614
RTN2 reticulon 2 -2.55905
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -2.5504
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -2.5176
SELENBP1 selenium binding protein 1 -2.5173
PRR15L proline rich 15-like -2.5018
ATP7A ATPase, Cu++ transporting, alpha polypeptide -2.48645
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) -2.4833
JADE2 jade family PHD finger 2 -2.46985
UNC13B unc-13 homolog B (C. elegans) -2.4602
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -2.4464
VAMP4 vesicle-associated membrane protein 4 -2.42403
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 -2.4239
SEZ6L2 seizure related 6 homolog (mouse)-like 2 -2.4163
CASP1 caspase 1, apoptosis-related cysteine peptidase -2.41446
SCGB2A1 secretoglobin, family 2A, member 1 -2.4138
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.4025
SRBD1 S1 RNA binding domain 1 -2.4023
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 -2.3978
SMG9 SMG9 nonsense mediated mRNA decay factor -2.3941
GFRA3 GDNF family receptor alpha 3 -2.3914
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) -2.3888
APOL3 apolipoprotein L, 3 -2.3798
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta -2.3678
TMPRSS3 transmembrane protease, serine 3 -2.3663
IRF1 interferon regulatory factor 1 -2.3625
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase -2.3493
KDM3B lysine (K)-specific demethylase 3B -2.34
LSG1 large 60S subunit nuclear export GTPase 1 -2.33295
PPOX protoporphyrinogen oxidase -2.3282
SCARA3 scavenger receptor class A, member 3 -2.3273
INTS9 integrator complex subunit 9 -2.3184
TSPAN8 tetraspanin 8 -2.3178
LOC124905743 low affinity immunoglobulin gamma Fc region receptor III-B -2.3113
CILK1 ciliogenesis associated kinase 1 -2.3016
GBE1 glucan (1,4-alpha-), branching enzyme 1 -2.2957
BMX BMX non-receptor tyrosine kinase -2.291
CKS1B CDC28 protein kinase regulatory subunit 1B -2.2886
NTSR1 neurotensin receptor 1 (high affinity) -2.2881
FGD1 FYVE, RhoGEF and PH domain containing 1 -2.261
CXCL14 chemokine (C-X-C motif) ligand 14 -2.2606
KLHL12 kelch-like family member 12 -2.2518
ERCC1 excision repair cross-complementation group 1 -2.2511
SFMBT1 Scm-like with four mbt domains 1 -2.2493
AADAC arylacetamide deacetylase -2.2363
PRKCD protein kinase C, delta -2.2337
SCGB1D2 secretoglobin, family 1D, member 2 -2.2337
RUBCNL rubicon like autophagy enhancer -2.23185
RAB8A RAB8A, member RAS oncogene family -2.2297
APCS amyloid P component, serum -2.2276
THADA thyroid adenoma associated -2.22515
HSPA2 heat shock 70kDa protein 2 -2.2241
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.2223
LGMN legumain -2.2147
SIPA1 signal-induced proliferation-associated 1 -2.2145
PARVB parvin, beta -2.214
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.2116
PAQR6 progestin and adipoQ receptor family member VI -2.206
EMD emerin -2.2023
TNRC6B trinucleotide repeat containing 6B -2.1978
DEFB1 defensin, beta 1 -2.194
EXOSC5 exosome component 5 -2.1936
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -2.18695
GBA1 glucosylceramidase beta 1 -2.18635
CCL7 chemokine (C-C motif) ligand 7 -2.1851
MGAM maltase-glucoamylase -2.1844
DEFA4 defensin, alpha 4, corticostatin -2.1803
S100A12 S100 calcium binding protein A12 -2.1749
SPRY2 sprouty homolog 2 (Drosophila) -2.1674
TMEM158 transmembrane protein 158 (gene/pseudogene) -2.1674
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 -2.1662
PMVK phosphomevalonate kinase -2.1656
NEFH neurofilament, heavy polypeptide -2.1648
AARSD1 alanyl-tRNA synthetase domain containing 1 -2.1645
CD2AP CD2-associated protein -2.1626
BOP1 block of proliferation 1 -2.16005
FPR1 formyl peptide receptor 1 -2.15915
OLAH oleoyl-ACP hydrolase -2.1589
AHDC1 AT hook, DNA binding motif, containing 1 -2.1578
CD38 CD38 molecule -2.1578
TDRD12 tudor domain containing 12 -2.153
SELL selectin L -2.1521
GRID1 glutamate receptor, ionotropic, delta 1 -2.15053
THOP1 thimet oligopeptidase 1 -2.1484
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -2.1468
SOCS3 suppressor of cytokine signaling 3 -2.1437
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.1432
GPAA1 glycosylphosphatidylinositol anchor attachment 1 -2.13607
TMC5 transmembrane channel-like 5 -2.1356
ADAM17 ADAM metallopeptidase domain 17 -2.13233
MED9 mediator complex subunit 9 -2.1311
MPZL1 myelin protein zero-like 1 -2.12497
ITGB4 integrin, beta 4 -2.12372
RBM10 RNA binding motif protein 10 -2.1189
BRD4 bromodomain containing 4 -2.11855
SGMS1 sphingomyelin synthase 1 -2.1177
FLOT1 flotillin 1 -2.11747
GNG12 guanine nucleotide binding protein (G protein), gamma 12 -2.1168
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -2.1045
STIM1 stromal interaction molecule 1 -2.1039
HOXB2 homeobox B2 -2.1036
ZNF239 zinc finger protein 239 -2.1022
MBOAT2 membrane bound O-acyltransferase domain containing 2 -2.1015
IL18 interleukin 18 -2.098
LIPT1 lipoyltransferase 1 -2.0977
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide -2.0969
ZBTB7C zinc finger and BTB domain containing 7C -2.0969
IL33 interleukin 33 -2.0943
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -2.0938
FGF6 fibroblast growth factor 6 -2.0935
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -2.0932
APOC3 apolipoprotein C-III -2.092
CHST10 carbohydrate sulfotransferase 10 -2.09
S100A9 S100 calcium binding protein A9 -2.089
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 -2.0823
TDO2 tryptophan 2,3-dioxygenase -2.08
GNLY granulysin -2.0728
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 -2.0695
CENPB centromere protein B, 80kDa -2.0615
FAM120C family with sequence similarity 120C -2.0614
F3 coagulation factor III (thromboplastin, tissue factor) -2.0543
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -2.05043
UBE2M ubiquitin-conjugating enzyme E2M -2.0491
GCLC glutamate-cysteine ligase, catalytic subunit -2.0487
METTL4 methyltransferase like 4 -2.048
RNF115 ring finger protein 115 -2.0461
SOCS2 suppressor of cytokine signaling 2 -2.04515
WDR70 WD repeat domain 70 -2.0443
PLS3 plastin 3 -2.04
GPR63 G protein-coupled receptor 63 -2.0373
EPPK1 epiplakin 1 -2.0352
GLCE glucuronic acid epimerase -2.0348
OSBP2 oxysterol binding protein 2 -2.0324
HROB homologous recombination factor with OB-fold -2.0275
HAX1 HCLS1 associated protein X-1 -2.0259
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A -2.0204
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -2.0201
FGL1 fibrinogen-like 1 -2.0185
DCAF10 DDB1 and CUL4 associated factor 10 -2.0163
SCN8A sodium channel, voltage gated, type VIII alpha subunit -2.0158
LINS1 lines homolog 1 -2.0133
YBX3 Y box binding protein 3 -2.0132
ACOD1 aconitate decarboxylase 1 -2.0113
THUMPD2 THUMP domain containing 2 -2.0097
ARID5A AT rich interactive domain 5A (MRF1-like) -2.006
FOXM1 forkhead box M1 -2.0016
FHIT fragile histidine triad -2.0012
CA6 carbonic anhydrase VI -2.0002