CRCGN014_HEPG2_3H:K17 Gene Set
Genes
55 genes differentially expressed following the CRCGN014_HEPG2_3H:K17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STK10
|
serine/threonine kinase 10
|
7.02325
|
|
CSK
|
c-src tyrosine kinase
|
4.51814
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.32979
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.5922
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
3.42484
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.12466
|
|
SKIC8
|
SKI8 subunit of superkiller complex
|
2.91009
|
|
KIF14
|
kinesin family member 14
|
2.77517
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
2.7651
|
|
ICAM1
|
intercellular adhesion molecule 1
|
2.73424
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.63561
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.59731
|
|
MAP7
|
microtubule-associated protein 7
|
2.56498
|
|
MICALL1
|
MICAL-like 1
|
2.50013
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.49165
|
|
STIMATE
|
STIM activating enhancer
|
2.41422
|
|
TBP
|
TATA box binding protein
|
2.33876
|
|
CCNF
|
cyclin F
|
2.33335
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.27764
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.21227
|
|
MBNL1
|
muscleblind-like splicing regulator 1
|
2.17183
|
|
HOXA10
|
homeobox A10
|
2.13533
|
|
HEATR3
|
HEAT repeat containing 3
|
2.10166
|
|
USP6NL
|
USP6 N-terminal like
|
2.09516
|
|
RAB31
|
RAB31, member RAS oncogene family
|
2.07855
|
|
SKIC2
|
SKI2 subunit of superkiller complex
|
2.06257
|
|
TSPAN6
|
tetraspanin 6
|
2.00566
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC25B
|
cell division cycle 25B
|
-4.82902
|
|
CCNB2
|
cyclin B2
|
-4.37545
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-4.15247
|
|
LAP3
|
leucine aminopeptidase 3
|
-4.08676
|
|
VAT1
|
vesicle amine transport 1
|
-4.03399
|
|
LDHD
|
lactate dehydrogenase D
|
-3.82421
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.29132
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.27623
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.22609
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.01956
|
|
WASHC4
|
WASH complex subunit 4
|
-2.53605
|
|
CCNB1
|
cyclin B1
|
-2.38352
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-2.37263
|
|
PSRC1
|
proline/serine-rich coiled-coil 1
|
-2.339
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.32641
|
|
REEP5
|
receptor accessory protein 5
|
-2.32002
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.28454
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.23681
|
|
EXT1
|
exostosin glycosyltransferase 1
|
-2.20836
|
|
RSPH6A
|
radial spoke head 6 homolog A (Chlamydomonas)
|
-2.18252
|
|
LY6H
|
lymphocyte antigen 6 complex, locus H
|
-2.1371
|
|
XDH
|
xanthine dehydrogenase
|
-2.13172
|
|
TOMM70
|
translocase of outer mitochondrial membrane 70
|
-2.11709
|
|
CD1B
|
CD1b molecule
|
-2.08692
|
|
APOL3
|
apolipoprotein L, 3
|
-2.06632
|
|
GBP2
|
guanylate binding protein 2, interferon-inducible
|
-2.05678
|
|
EDN1
|
endothelin 1
|
-2.02272
|
|
NUSAP1
|
nucleolar and spindle associated protein 1
|
-2.00869
|
