CRCGN014_HEPG2_3H:K18 Gene Set
Genes
42 genes differentially expressed following the CRCGN014_HEPG2_3H:K18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
4.59915
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.34218
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.653
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.39569
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.28362
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.23151
|
|
HOXA10
|
homeobox A10
|
3.11974
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.09546
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.08858
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.99058
|
|
CSK
|
c-src tyrosine kinase
|
2.79328
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.53084
|
|
SPTAN1
|
spectrin, alpha, non-erythrocytic 1
|
2.49702
|
|
SFTPB
|
surfactant protein B
|
2.38378
|
|
KIF14
|
kinesin family member 14
|
2.21233
|
|
ZBTB18
|
zinc finger and BTB domain containing 18
|
2.16199
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.13432
|
|
SHB
|
Src homology 2 domain containing adaptor protein B
|
2.11819
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.11322
|
|
MOK
|
MOK protein kinase
|
2.10881
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
2.04166
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.02698
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-4.28277
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.74422
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.68725
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.48363
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.16287
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.15449
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.00875
|
|
REEP5
|
receptor accessory protein 5
|
-2.76942
|
|
MTA1
|
metastasis associated 1
|
-2.76366
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
-2.62801
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-2.61486
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.5236
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.19326
|
|
SPAG4
|
sperm associated antigen 4
|
-2.17704
|
|
LDHD
|
lactate dehydrogenase D
|
-2.11766
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.09808
|
|
CLDND1
|
claudin domain containing 1
|
-2.05048
|
|
VAT1
|
vesicle amine transport 1
|
-2.03275
|
|
NVL
|
nuclear VCP-like
|
-2.026
|
|
CDC25B
|
cell division cycle 25B
|
-2.00795
|
