CRCGN014_HEPG2_3H:K21 Gene Set
Genes
32 genes differentially expressed following the CRCGN014_HEPG2_3H:K21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
7.81454
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
6.21243
|
|
GATA3
|
GATA binding protein 3
|
3.44164
|
|
EPHB2
|
EPH receptor B2
|
3.35228
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
3.32082
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.18898
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
3.07895
|
|
CYCS
|
cytochrome c, somatic
|
2.80944
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.70778
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.55966
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.3911
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.34683
|
|
UBQLN2
|
ubiquilin 2
|
2.22993
|
|
COCH
|
cochlin
|
2.03765
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-9.4395
|
|
LDHD
|
lactate dehydrogenase D
|
-7.63367
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-6.22503
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.93224
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.87905
|
|
ZNF586
|
zinc finger protein 586
|
-5.79833
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.04656
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.02268
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.88817
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.55893
|
|
TLR4
|
toll-like receptor 4
|
-3.26043
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.70665
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.47383
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.39277
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.26129
|
|
NQO2
|
NAD(P)H dehydrogenase, quinone 2
|
-2.02616
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-2.01808
|
|
MRS2
|
MRS2 magnesium transporter
|
-2.01196
|
