CRCGN014_HEPG2_3H:K22 Gene Set
Genes
38 genes differentially expressed following the CRCGN014_HEPG2_3H:K22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
7.31135
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
5.16772
|
|
STAP2
|
signal transducing adaptor family member 2
|
4.87186
|
|
STK10
|
serine/threonine kinase 10
|
4.36509
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
4.29576
|
|
STIMATE
|
STIM activating enhancer
|
4.2572
|
|
KLHL9
|
kelch-like family member 9
|
4.06775
|
|
CYCS
|
cytochrome c, somatic
|
4.02479
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.65231
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.6274
|
|
MAMLD1
|
mastermind-like domain containing 1
|
2.61798
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.38352
|
|
CYB561
|
cytochrome b561
|
2.33022
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.31671
|
|
PFDN2
|
prefoldin subunit 2
|
2.27811
|
|
MAP7
|
microtubule-associated protein 7
|
2.27785
|
|
MPC2
|
mitochondrial pyruvate carrier 2
|
2.27293
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.07676
|
|
RPA3
|
replication protein A3, 14kDa
|
2.07061
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
2.04737
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-5.8052
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.9563
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.52223
|
|
ZNF586
|
zinc finger protein 586
|
-4.36779
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.17575
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-3.61544
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-3.44981
|
|
CCNB1
|
cyclin B1
|
-3.15517
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.94138
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-2.61994
|
|
RNF167
|
ring finger protein 167
|
-2.60137
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.56642
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.44524
|
|
LDHD
|
lactate dehydrogenase D
|
-2.35754
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.35156
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.29098
|
|
HOXD11
|
homeobox D11
|
-2.25226
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.20379
|
