CRCGN014_HEPG2_3H:L04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description p-nitroaniline 39.8 um perturbation at 3 h in HEPG2 (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN014_HEPG2_3H:L04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
BLMH bleomycin hydrolase 4.26116
PPARG peroxisome proliferator-activated receptor gamma 4.17326
UBQLN2 ubiquilin 2 3.88671
NOTCH1 notch 1 3.63539
ABHD6 abhydrolase domain containing 6 3.20345
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.17973
MAP7 microtubule-associated protein 7 2.81127
CYCS cytochrome c, somatic 2.68595
KIF14 kinesin family member 14 2.59624
JPT2 Jupiter microtubule associated homolog 2 2.51114
SFTPB surfactant protein B 2.48261
UFM1 ubiquitin-fold modifier 1 2.269
TREM1 triggering receptor expressed on myeloid cells 1 2.18855
CEMIP2 cell migration inducing hyaluronidase 2 2.17369
DCP2 decapping mRNA 2 2.13088
CARMIL1 capping protein regulator and myosin 1 linker 1 2.10624
CDC45 cell division cycle 45 2.08342

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -7.95336
OXA1L oxidase (cytochrome c) assembly 1-like -5.80881
CCDC86 coiled-coil domain containing 86 -4.21978
CDC20 cell division cycle 20 -4.15262
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.94796
PTPRK protein tyrosine phosphatase, receptor type, K -3.84539
PCNA proliferating cell nuclear antigen -3.81513
WDR7 WD repeat domain 7 -3.51064
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -3.22749
BDH1 3-hydroxybutyrate dehydrogenase, type 1 -3.06189
TLCD3A TLC domain containing 3A -2.78247
NAT9 N-acetyltransferase 9 (GCN5-related, putative) -2.48192
CCN6 cellular communication network factor 6 -2.38447
CNTLN centlein, centrosomal protein -2.0769
AUH AU RNA binding protein/enoyl-CoA hydratase -2.05145
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 -2.02919
MRPS2 mitochondrial ribosomal protein S2 -2.0022