CRCGN014_HEPG2_3H:L06 Gene Set
Genes
47 genes differentially expressed following the CRCGN014_HEPG2_3H:L06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
6.33804
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
5.26485
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.22653
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.85179
|
|
UBQLN2
|
ubiquilin 2
|
4.19422
|
|
CYCS
|
cytochrome c, somatic
|
3.72847
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.28333
|
|
HDGFL3
|
HDGF like 3
|
3.11503
|
|
BLMH
|
bleomycin hydrolase
|
3.07081
|
|
GPATCH8
|
G patch domain containing 8
|
2.95179
|
|
CHN1
|
chimerin 1
|
2.54888
|
|
CCNF
|
cyclin F
|
2.46293
|
|
PRPF38B
|
pre-mRNA processing factor 38B
|
2.45346
|
|
HOXB3
|
homeobox B3
|
2.37027
|
|
PCDHB11
|
protocadherin beta 11
|
2.36747
|
|
SAMHD1
|
SAM domain and HD domain 1
|
2.34674
|
|
MRPS33
|
mitochondrial ribosomal protein S33
|
2.27643
|
|
DHX16
|
DEAH (Asp-Glu-Ala-His) box polypeptide 16
|
2.22183
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.1997
|
|
SLC25A46
|
solute carrier family 25, member 46
|
2.19417
|
|
GIPC1
|
GIPC PDZ domain containing family, member 1
|
2.17404
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
2.16869
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.14068
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.12795
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.11645
|
|
CORO1A
|
coronin, actin binding protein, 1A
|
2.0304
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
-5.16473
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-4.7974
|
|
CCNB2
|
cyclin B2
|
-4.53854
|
|
ZNF586
|
zinc finger protein 586
|
-4.41601
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.86278
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.84712
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.6138
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
-3.44998
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.41288
|
|
RAI14
|
retinoic acid induced 14
|
-3.35388
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.33885
|
|
PEG10
|
paternally expressed 10
|
-3.07374
|
|
EGF
|
epidermal growth factor
|
-2.5188
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.49826
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.42462
|
|
PLA2G12A
|
phospholipase A2, group XIIA
|
-2.36623
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.18102
|
|
PDZK1
|
PDZ domain containing 1
|
-2.12808
|
|
SNX16
|
sorting nexin 16
|
-2.07162
|
|
BAD
|
BCL2-associated agonist of cell death
|
-2.06369
|
|
NUSAP1
|
nucleolar and spindle associated protein 1
|
-2.04118
|
