CRCGN014_HEPG2_3H:L08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4-chloro-4'-aminodiphenylether 39.2 um perturbation at 3 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

54 genes differentially expressed following the CRCGN014_HEPG2_3H:L08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DDIT4 DNA-damage-inducible transcript 4 9.42652
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.91853
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 4.80095
HYOU1 hypoxia up-regulated 1 4.64404
AMDHD2 amidohydrolase domain containing 2 4.29599
CCNF cyclin F 3.97766
STIMATE STIM activating enhancer 3.91089
CSK c-src tyrosine kinase 3.86761
ADRB2 adrenoceptor beta 2, surface 3.62274
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.59601
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 3.58744
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.54936
HPRT1 hypoxanthine phosphoribosyltransferase 1 3.51633
CCDC92 coiled-coil domain containing 92 3.22772
CDK19 cyclin-dependent kinase 19 3.13993
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 3.05935
HOXA10 homeobox A10 2.86541
TRIB3 tribbles pseudokinase 3 2.80752
PRKCH protein kinase C, eta 2.79662
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.78185
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.53518
ABHD6 abhydrolase domain containing 6 2.52074
LPAR2 lysophosphatidic acid receptor 2 2.48266
GATA2 GATA binding protein 2 2.46538
ALAS1 5'-aminolevulinate synthase 1 2.44867
TBC1D10C TBC1 domain family, member 10C 2.43874
MANF mesencephalic astrocyte-derived neurotrophic factor 2.43126
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.17893
RPL39L ribosomal protein L39-like 2.17564
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.12381
BAG3 BCL2-associated athanogene 3 2.0676
KANK3 KN motif and ankyrin repeat domains 3 2.01092

decreased expression

Symbol Name Standardized Value
CDC20 cell division cycle 20 -6.22538
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -6.14713
ZNF586 zinc finger protein 586 -5.68099
OXA1L oxidase (cytochrome c) assembly 1-like -4.64874
PRPF4 pre-mRNA processing factor 4 -3.84263
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -3.72203
CCNB1 cyclin B1 -3.50489
PCNA proliferating cell nuclear antigen -2.98298
TCERG1 transcription elongation regulator 1 -2.94597
CCNB2 cyclin B2 -2.88549
NT5DC2 5'-nucleotidase domain containing 2 -2.87813
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.85455
SLC35F2 solute carrier family 35, member F2 -2.84816
PEG10 paternally expressed 10 -2.77121
FABP5 fatty acid binding protein 5 (psoriasis-associated) -2.53082
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.37609
FGFR4 fibroblast growth factor receptor 4 -2.37151
CAPNS1 calpain, small subunit 1 -2.30061
GTF2A2 general transcription factor IIA, 2, 12kDa -2.23621
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -2.18459
GNAS GNAS complex locus -2.05251
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.01913