CRCGN014_HEPG2_3H:L09 Gene Set
Genes
44 genes differentially expressed following the CRCGN014_HEPG2_3H:L09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
5.4015
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.47289
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.16186
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.73671
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.52222
|
|
NOTCH1
|
notch 1
|
3.29522
|
|
EPN2
|
epsin 2
|
3.2223
|
|
PRKCH
|
protein kinase C, eta
|
3.11406
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.09541
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.99704
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.8699
|
|
VGLL4
|
vestigial-like family member 4
|
2.73474
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.66635
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.66524
|
|
MYLK
|
myosin light chain kinase
|
2.56349
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.47372
|
|
CRYGD
|
crystallin, gamma D
|
2.46473
|
|
MPPED1
|
metallophosphoesterase domain containing 1
|
2.45196
|
|
ZNF276
|
zinc finger protein 276
|
2.33784
|
|
HUNK
|
hormonally up-regulated Neu-associated kinase
|
2.29437
|
|
SFTPB
|
surfactant protein B
|
2.195
|
|
MYOG
|
myogenin (myogenic factor 4)
|
2.07103
|
|
BPNT2
|
3'(2'), 5'-bisphosphate nucleotidase 2
|
2.06186
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.05412
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-5.59523
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-4.6359
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.24163
|
|
VAT1
|
vesicle amine transport 1
|
-3.86085
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.84281
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.57082
|
|
TLR4
|
toll-like receptor 4
|
-3.43368
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.4106
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.21836
|
|
GNAS
|
GNAS complex locus
|
-2.92987
|
|
GTF2H4
|
general transcription factor IIH, polypeptide 4, 52kDa
|
-2.70212
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.62169
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-2.61378
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-2.39099
|
|
ANKRD36C
|
ankyrin repeat domain 36C
|
-2.17182
|
|
DHX8
|
DEAH (Asp-Glu-Ala-His) box polypeptide 8
|
-2.1646
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.10635
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.10616
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.04633
|
|
CDC25B
|
cell division cycle 25B
|
-2.02272
|
