CRCGN014_HEPG2_3H:L16 Gene Set
Genes
47 genes differentially expressed following the CRCGN014_HEPG2_3H:L16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STIMATE
|
STIM activating enhancer
|
5.93251
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
4.58773
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
4.31566
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
4.13663
|
|
UBQLN2
|
ubiquilin 2
|
3.55801
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.53762
|
|
NOTCH1
|
notch 1
|
3.49479
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.39248
|
|
KLHL21
|
kelch-like family member 21
|
3.29804
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
3.27142
|
|
CEP57
|
centrosomal protein 57kDa
|
3.22891
|
|
IER3
|
immediate early response 3
|
3.11346
|
|
GNAI2
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
|
3.02316
|
|
CYCS
|
cytochrome c, somatic
|
2.9995
|
|
PRKCH
|
protein kinase C, eta
|
2.92673
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.87018
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.86047
|
|
ZBTB18
|
zinc finger and BTB domain containing 18
|
2.76495
|
|
BAMBI
|
BMP and activin membrane-bound inhibitor
|
2.74743
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
2.60055
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.46261
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.4511
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.38393
|
|
RBKS
|
ribokinase
|
2.2441
|
|
RRAGA
|
Ras-related GTP binding A
|
2.14104
|
|
JMJD1C
|
jumonji domain containing 1C
|
2.02969
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.01933
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.56563
|
|
CCNB2
|
cyclin B2
|
-6.48919
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-4.84686
|
|
PSRC1
|
proline/serine-rich coiled-coil 1
|
-4.36369
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.96461
|
|
CCNB1
|
cyclin B1
|
-3.68124
|
|
VAT1
|
vesicle amine transport 1
|
-3.32236
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-3.20111
|
|
WASHC4
|
WASH complex subunit 4
|
-3.10496
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.02756
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.95172
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.75174
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.59869
|
|
ZNF586
|
zinc finger protein 586
|
-2.58116
|
|
HMG20B
|
high mobility group 20B
|
-2.40536
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.32862
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-2.14048
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.1344
|
|
PMM2
|
phosphomannomutase 2
|
-2.12073
|
|
SNX11
|
sorting nexin 11
|
-2.01817
|
