CRCGN014_HEPG2_3H:L18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-[(1,1,2,2-tetrachloroethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1h-isoindole-1,3(2h)-dione 20.84 um perturbation at 3 h in HEPG2 (Carcinogenome)
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Genes

808 genes differentially expressed following the CRCGN014_HEPG2_3H:L18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MSRA methionine sulfoxide reductase A 8.79231
SHB Src homology 2 domain containing adaptor protein B 7.78318
UBE2L6 ubiquitin-conjugating enzyme E2L 6 7.46361
CCNA1 cyclin A1 6.9993
HSPA1A heat shock 70kDa protein 1A 6.43478
PPARG peroxisome proliferator-activated receptor gamma 6.424
TERT telomerase reverse transcriptase 6.30951
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 6.05049
TRAPPC6A trafficking protein particle complex 6A 5.85271
CYCS cytochrome c, somatic 5.84698
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 5.76603
STAP2 signal transducing adaptor family member 2 5.44482
CAPN1 calpain 1, (mu/I) large subunit 5.34307
NR1H2 nuclear receptor subfamily 1, group H, member 2 5.26126
MAP7 microtubule-associated protein 7 5.18428
LOC122526780 uncharacterized LOC122526780 5.14302
TIMP2 TIMP metallopeptidase inhibitor 2 5.11995
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 5.01827
ATP11B ATPase, class VI, type 11B 4.84955
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 4.84341
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 4.79283
PRKX protein kinase, X-linked 4.77778
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 4.7644
EDN1 endothelin 1 4.74507
MEST mesoderm specific transcript 4.73472
CTSD cathepsin D 4.54296
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 4.35882
NOTCH1 notch 1 4.35324
PPP1R13B protein phosphatase 1, regulatory subunit 13B 4.32148
CIAO3 cytosolic iron-sulfur assembly component 3 4.25494
IL1B interleukin 1, beta 4.25408
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 4.20048
IFNAR1 interferon (alpha, beta and omega) receptor 1 4.19948
PTK2 protein tyrosine kinase 2 4.18081
RAI14 retinoic acid induced 14 4.14994
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 4.10378
CCDC85B coiled-coil domain containing 85B 4.06309
SMIM40 small integral membrane protein 40 4.05603
PTPRK protein tyrosine phosphatase, receptor type, K 4.03713
HTRA1 HtrA serine peptidase 1 3.9705
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 3.95089
HOXA10 homeobox A10 3.94125
HEBP1 heme binding protein 1 3.94007
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 3.93463
NPDC1 neural proliferation, differentiation and control, 1 3.90897
ALAS1 5'-aminolevulinate synthase 1 3.83894
UBQLN2 ubiquilin 2 3.79863
HOXA10-HOXA9 HOXA10-HOXA9 readthrough 3.79545
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 3.78348
PTK2B protein tyrosine kinase 2 beta 3.73112
TRIM13 tripartite motif containing 13 3.69029
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 3.64259
ADIRF adipogenesis regulatory factor 3.62907
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 3.61801
STK10 serine/threonine kinase 10 3.54906
FAIM Fas apoptotic inhibitory molecule 3.51124
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 3.50959
SOCS2 suppressor of cytokine signaling 2 3.50874
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 3.49073
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 3.47539
GAS6 growth arrest-specific 6 3.44353
CAB39L calcium binding protein 39-like 3.41286
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 3.38986
SNX7 sorting nexin 7 3.34531
GHR growth hormone receptor 3.32221
CSNK1E casein kinase 1, epsilon 3.30281
ARL4C ADP-ribosylation factor-like 4C 3.29694
PNKP polynucleotide kinase 3'-phosphatase 3.28561
DCAF4 DDB1 and CUL4 associated factor 4 3.27169
NVL nuclear VCP-like 3.26016
PRSS16 protease, serine, 16 (thymus) 3.23217
BPHL biphenyl hydrolase-like (serine hydrolase) 3.19755
TBXA2R thromboxane A2 receptor 3.18863
BNC2 basonuclin 2 3.18519
POLH polymerase (DNA directed), eta 3.17296
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 3.16339
SPATA7 spermatogenesis associated 7 3.14799
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 3.14299
TESK1 testis-specific kinase 1 3.1271
IPO13 importin 13 3.11474
ITFG1 integrin alpha FG-GAP repeat containing 1 3.11161
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 3.10205
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 3.06026
PTCD2 pentatricopeptide repeat domain 2 3.05306
FBXL12 F-box and leucine-rich repeat protein 12 3.03361
ZNF141 zinc finger protein 141 3.03238
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 3.02704
SLC75A1 solute carrier family 75 member 1 3.00632
ZBTB3 zinc finger and BTB domain containing 3 3.0052
RAB11FIP2 RAB11 family interacting protein 2 (class I) 3.00154
H2AJ H2A.J histone 2.9981
TMEM19 transmembrane protein 19 2.99726
CAMK1D calcium/calmodulin-dependent protein kinase ID 2.99249
USP53 ubiquitin specific peptidase 53 2.97855
GRB7 growth factor receptor-bound protein 7 2.97129
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.96359
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.9508
MEF2C myocyte enhancer factor 2C 2.9469
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.9216
TRABD TraB domain containing 2.91284
RASA2 RAS p21 protein activator 2 2.91007
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 2.91003
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 2.90734
MOB3B MOB kinase activator 3B 2.90326
ZNF362 zinc finger protein 362 2.90104
MBOAT7 membrane bound O-acyltransferase domain containing 7 2.90041
ARMCX4 armadillo repeat containing, X-linked 4 2.87831
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 2.87672
BAMBI BMP and activin membrane-bound inhibitor 2.87468
PRAMEF10 PRAME family member 10 2.87178
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.8684
POLM polymerase (DNA directed), mu 2.86653
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.83953
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 2.83403
TENT4A terminal nucleotidyltransferase 4A 2.82064
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 2.81733
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 2.81607
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2 2.81126
PRR15L proline rich 15-like 2.81116
BZW2 basic leucine zipper and W2 domains 2 2.8104
THSD4 thrombospondin, type I, domain containing 4 2.8074
PDE9A phosphodiesterase 9A 2.79776
BARX1 BARX homeobox 1 2.78893
TNFAIP8L2-SCNM1 TNFAIP8L2-SCNM1 readthrough 2.78841
FGF5 fibroblast growth factor 5 2.78761
MUC2 mucin 2, oligomeric mucus/gel-forming 2.78045
APOBR apolipoprotein B receptor 2.76999
EMC10 ER membrane protein complex subunit 10 2.7694
BAD BCL2-associated agonist of cell death 2.7643
CLDN14 claudin 14 2.76243
RAB43 RAB43, member RAS oncogene family 2.75881
PGAP4 post-GPI attachment to proteins GalNAc transferase 4 2.74956
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 2.74946
MUC1 mucin 1, cell surface associated 2.73983
CAPN9 calpain 9 2.73821
TSC22D3 TSC22 domain family, member 3 2.72778
ZNF124 zinc finger protein 124 2.72537
CCL2 chemokine (C-C motif) ligand 2 2.72156
EXD3 exonuclease 3'-5' domain containing 3 2.72034
IGFBP3 insulin-like growth factor binding protein 3 2.71926
HYI hydroxypyruvate isomerase (putative) 2.71615
SQOR sulfide quinone oxidoreductase 2.71197
C5AR2 complement component 5a receptor 2 2.70698
BEST2 bestrophin 2 2.70525
NT5E 5'-nucleotidase, ecto (CD73) 2.69969
GADD45A growth arrest and DNA-damage-inducible, alpha 2.69727
ATOSB atos homolog B 2.69571
FST follistatin 2.69493
HSF1 heat shock transcription factor 1 2.68326
SBSPON somatomedin B and thrombospondin, type 1 domain containing 2.67986
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.67482
RUSC2 RUN and SH3 domain containing 2 2.67197
ARMCX1 armadillo repeat containing, X-linked 1 2.67127
TDRD3 tudor domain containing 3 2.67036
NOSIP nitric oxide synthase interacting protein 2.66991
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.66985
CEP15 centrosomal protein 15 2.66957
EXO5 exonuclease 5 2.66955
DNM1 dynamin 1 2.66577
CCDC71 coiled-coil domain containing 71 2.66345
RFTN1 raftlin, lipid raft linker 1 2.65839
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 2.65679
CDK3 cyclin-dependent kinase 3 2.65629
AIRIM AFG2 interacting ribosome maturation factor 2.65574
EIF3G eukaryotic translation initiation factor 3, subunit G 2.65495
ICAM5 intercellular adhesion molecule 5, telencephalin 2.64471
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 2.6422
KLHDC8A kelch domain containing 8A 2.64024
INA internexin neuronal intermediate filament protein, alpha 2.63804
AMELY amelogenin, Y-linked 2.63452
TDRD12 tudor domain containing 12 2.62674
PTMS parathymosin 2.61957
PCDHGA11 protocadherin gamma subfamily A, 11 2.6186
HELLS helicase, lymphoid-specific 2.61497
GSDMB gasdermin B 2.61397
LPAR3 lysophosphatidic acid receptor 3 2.61208
PCLO piccolo presynaptic cytomatrix protein 2.61071
GRPR gastrin-releasing peptide receptor 2.60671
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 2.60026
JUN jun proto-oncogene 2.59934
RNF186 ring finger protein 186 2.59663
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 2.5936
STARD8 StAR-related lipid transfer (START) domain containing 8 2.5926
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 2.59139
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.58451
TMEM143 transmembrane protein 143 2.57955
IGFBP5 insulin-like growth factor binding protein 5 2.57953
FEZF2 FEZ family zinc finger 2 2.57951
STX4 syntaxin 4 2.5782
RAB21 RAB21, member RAS oncogene family 2.57577
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.57494
EXT1 exostosin glycosyltransferase 1 2.57451
PRDM9 PR domain containing 9 2.56586
ZG16 zymogen granule protein 16 2.5655
FOXH1 forkhead box H1 2.56327
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 2.54134
RBM41 RNA binding motif protein 41 2.53995
FZD1 frizzled class receptor 1 2.53954
GPR85 G protein-coupled receptor 85 2.53152
ECHDC3 enoyl CoA hydratase domain containing 3 2.52849
SEC14L4 SEC14-like 4 (S. cerevisiae) 2.52056
PELI1 pellino E3 ubiquitin protein ligase 1 2.51179
HAO2 hydroxyacid oxidase 2 (long chain) 2.51035
TAGLN3 transgelin 3 2.50991
CLDN17 claudin 17 2.50906
KIAA1614 KIAA1614 2.50562
OVOL3 ovo-like zinc finger 3 2.50528
MOCS1 molybdenum cofactor synthesis 1 2.50253
ZKSCAN4 zinc finger with KRAB and SCAN domains 4 2.50032
ILK integrin-linked kinase 2.49842
LUZP4 leucine zipper protein 4 2.49553
QTMAN queuosine-tRNA mannosyltransferase 2.49544
MBTD1 mbt domain containing 1 2.49529
NKAIN1 Na+/K+ transporting ATPase interacting 1 2.49389
TMSB15C thymosin beta 15C 2.49302
SCN8A sodium channel, voltage gated, type VIII alpha subunit 2.49266
OR5I1 olfactory receptor, family 5, subfamily I, member 1 2.49253
MPC2 mitochondrial pyruvate carrier 2 2.48993
MYOF myoferlin 2.48982
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.48951
ZFP36 ZFP36 ring finger protein 2.48511
LRRC19 leucine rich repeat containing 19 2.48373
ACVR2B activin A receptor, type IIB 2.48192
OR2C1 olfactory receptor, family 2, subfamily C, member 1 2.47868
SCN4A sodium channel, voltage gated, type IV alpha subunit 2.46802
ZNF215 zinc finger protein 215 2.4577
CD9 CD9 molecule 2.45578
RARG retinoic acid receptor, gamma 2.4516
AQP8 aquaporin 8 2.45011
ZNG1A Zn regulated GTPase metalloprotein activator 1A 2.44993
TRHDE thyrotropin-releasing hormone degrading enzyme 2.44958
RTL8A retrotransposon Gag like 8A 2.44818
FGFR2 fibroblast growth factor receptor 2 2.44611
DENND1B DENN/MADD domain containing 1B 2.44368
CXCR4 chemokine (C-X-C motif) receptor 4 2.439
CRYBB1 crystallin, beta B1 2.43397
NIPAL2 NIPA-like domain containing 2 2.42751
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 2.42649
CNOT3 CCR4-NOT transcription complex, subunit 3 2.41941
TAF1B TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa 2.41601
PLXNB2 plexin B2 2.41589
BCL2L14 BCL2-like 14 (apoptosis facilitator) 2.41325
TMEM40 transmembrane protein 40 2.41301
DUSP4 dual specificity phosphatase 4 2.40921
KIFBP kinesin family binding protein 2.40794
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 2.40693
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.40603
CDC45 cell division cycle 45 2.40038
ERC2 ELKS/RAB6-interacting/CAST family member 2 2.399
PLA2G2F phospholipase A2, group IIF 2.39718
ANGPT2 angiopoietin 2 2.39595
UBE2W ubiquitin-conjugating enzyme E2W (putative) 2.39586
NHERF4 NHERF family PDZ scaffold protein 4 2.39317
FOXD1 forkhead box D1 2.3905
HSF4 heat shock transcription factor 4 2.38939
PRDM14 PR domain containing 14 2.38917
CRIPTO3 cripto, EGF-CFC family member 3 2.38522
COLEC10 collectin sub-family member 10 (C-type lectin) 2.38334
EFNB3 ephrin-B3 2.38237
IMPG2 interphotoreceptor matrix proteoglycan 2 2.38031
LYN LYN proto-oncogene, Src family tyrosine kinase 2.37572
CORO1A coronin, actin binding protein, 1A 2.37537
IMPACT impact RWD domain protein 2.36721
IVNS1ABP influenza virus NS1A binding protein 2.36716
INSRR insulin receptor-related receptor 2.36705
SH2D3A SH2 domain containing 3A 2.36606
LCN2 lipocalin 2 2.36279
GUCY2F guanylate cyclase 2F, retinal 2.35988
EID1 EP300 interacting inhibitor of differentiation 1 2.35943
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 2.35759
HSPA1B heat shock 70kDa protein 1B 2.35717
ESM1 endothelial cell-specific molecule 1 2.3568
THAP10 THAP domain containing 10 2.34824
PRDM12 PR domain containing 12 2.34708
TUBAL3 tubulin, alpha-like 3 2.34315
VASP vasodilator-stimulated phosphoprotein 2.33837
GPR132 G protein-coupled receptor 132 2.33749
HOXD9 homeobox D9 2.33659
RASL11B RAS-like, family 11, member B 2.3345
GSE1 Gse1 coiled-coil protein 2.33441
HOXD1 homeobox D1 2.33436
INHBC inhibin, beta C 2.3309
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa 2.32887
KIF24 kinesin family member 24 2.3279
CYB561 cytochrome b561 2.32538
NAXD NAD(P)HX dehydratase 2.32352
ANKRD6 ankyrin repeat domain 6 2.32268
ZNF514 zinc finger protein 514 2.32183
ANO1 anoctamin 1, calcium activated chloride channel 2.32168
PTPN6 protein tyrosine phosphatase, non-receptor type 6 2.32019
ELMO3 engulfment and cell motility 3 2.32015
BNC1 basonuclin 1 2.31914
ARHGAP8 Rho GTPase activating protein 8 2.31825
SSTR3 somatostatin receptor 3 2.31665
SYT13 synaptotagmin XIII 2.31337
CDCA8 cell division cycle associated 8 2.31305
POU6F2 POU class 6 homeobox 2 2.31195
FMNL3 formin-like 3 2.31184
IL36R interleukin 36 receptor 2.3075
ANKRD40CL ANKRD40 C-terminal like 2.30544
H1-5 H1.5 linker histone, cluster member 2.30408
ELL3 elongation factor RNA polymerase II-like 3 2.30405
KRTAP2-3 keratin associated protein 2-3 2.30315
TMEM158 transmembrane protein 158 (gene/pseudogene) 2.30227
USP29 ubiquitin specific peptidase 29 2.29927
PARP6 poly (ADP-ribose) polymerase family, member 6 2.29896
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 2.29374
HOXB8 homeobox B8 2.292
SCRN3 secernin 3 2.29197
MAMLD1 mastermind-like domain containing 1 2.29118
SUGCT succinyl-CoA:glutarate-CoA transferase 2.2901
RGCC regulator of cell cycle 2.28991
PCDHGA10 protocadherin gamma subfamily A, 10 2.28813
BCO1 beta-carotene oxygenase 1 2.2874
STEAP1B STEAP family member 1B 2.28666
EPS8L1 EPS8-like 1 2.28446
GPC1 glypican 1 2.2828
CRABP2 cellular retinoic acid binding protein 2 2.28222
RIPK4 receptor-interacting serine-threonine kinase 4 2.28218
EPN3 epsin 3 2.28194
LRRK1 leucine-rich repeat kinase 1 2.28177
TES testin LIM domain protein 2.27982
FCHO1 FCH domain only 1 2.27811
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 2.27451
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 2.27434
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 2.27383
IFT27 intraflagellar transport 27 2.27358
WNT7B wingless-type MMTV integration site family, member 7B 2.27044
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 2.26944
GMEB1 glucocorticoid modulatory element binding protein 1 2.26775
COL19A1 collagen, type XIX, alpha 1 2.26553
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 2.2654
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.2646
RTN2 reticulon 2 2.26385
GMPR guanosine monophosphate reductase 2.2631
IL25 interleukin 25 2.26246
TRIM15 tripartite motif containing 15 2.26183
CTNND1 catenin (cadherin-associated protein), delta 1 2.26179
GJB4 gap junction protein, beta 4, 30.3kDa 2.26139
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 2.25849
ANXA1 annexin A1 2.25461
SYNPO2 synaptopodin 2 2.25411
CTBP2 C-terminal binding protein 2 2.25375
ZNF250 zinc finger protein 250 2.25325
AVEN apoptosis, caspase activation inhibitor 2.24764
SPI1 Spi-1 proto-oncogene 2.24656
CLDN7 claudin 7 2.2416
RXFP3 relaxin/insulin-like family peptide receptor 3 2.23854
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 2.23782
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 2.23779
MAPK12 mitogen-activated protein kinase 12 2.23773
SSTR4 somatostatin receptor 4 2.23694
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 2.23587
JAG2 jagged 2 2.23575
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 2.2351
LEFTY1 left-right determination factor 1 2.23393
ISYNA1 inositol-3-phosphate synthase 1 2.23297
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 2.23187
YPEL5 yippee-like 5 (Drosophila) 2.23178
MGAM2 maltase-glucoamylase 2 (putative) 2.2313
KLK15 kallikrein-related peptidase 15 2.22943
JCAD junctional cadherin 5 associated 2.22627
GPRC5D G protein-coupled receptor, class C, group 5, member D 2.22603
KANSL1L KAT8 regulatory NSL complex subunit 1-like 2.22597
NMBR neuromedin B receptor 2.22571
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.22567
SYNJ2BP synaptojanin 2 binding protein 2.22556
BTG3 BTG family, member 3 2.22522
MAN2C1 mannosidase, alpha, class 2C, member 1 2.2249
VENTX VENT homeobox 2.22484
PCDHGB5 protocadherin gamma subfamily B, 5 2.22403
EYA3 EYA transcriptional coactivator and phosphatase 3 2.22202
NMRK1 nicotinamide riboside kinase 1 2.22179
GPALPP1 GPALPP motifs containing 1 2.22156
EPHB1 EPH receptor B1 2.22092
RLN2 relaxin 2 2.22086
HDAC9 histone deacetylase 9 2.21991
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.21363
ATOH1 atonal homolog 1 (Drosophila) 2.21304
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 2.213
TCEA2 transcription elongation factor A (SII), 2 2.21252
SIX3 SIX homeobox 3 2.21071
DMTF1 cyclin D binding myb-like transcription factor 1 2.20772
TNNT1 troponin T type 1 (skeletal, slow) 2.20691
TEX11 testis expressed 11 2.20419
KIAA1549L KIAA1549-like 2.20358
ZNF692 zinc finger protein 692 2.2035
SIGLEC6 sialic acid binding Ig-like lectin 6 2.20234
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.20164
VEGFA vascular endothelial growth factor A 2.20158
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.20056
ZNF358 zinc finger protein 358 2.1983
MUC3B mucin 3B, cell surface associated 2.19797
PXDN peroxidasin 2.19757
EN1 engrailed homeobox 1 2.19737
NACAD NAC alpha domain containing 2.197
IER5 immediate early response 5 2.1965
CDX1 caudal type homeobox 1 2.19642
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) 2.19624
DIPK2B divergent protein kinase domain 2B 2.19405
ARHGAP22 Rho GTPase activating protein 22 2.19016
ZNF623 zinc finger protein 623 2.1886
HPCAL1 hippocalcin-like 1 2.18712
PID1 phosphotyrosine interaction domain containing 1 2.1867
CDHR5 cadherin-related family member 5 2.1853
MYO19 myosin XIX 2.18414
WRNIP1 Werner helicase interacting protein 1 2.17975
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 2.17865
GLYAT glycine-N-acyltransferase 2.1785
GREM1 gremlin 1, DAN family BMP antagonist 2.17631
DSCC1 DNA replication and sister chromatid cohesion 1 2.17577
TMEM259 transmembrane protein 259 2.17508
H2BC3 H2B clustered histone 3 2.17391
MYBPH myosin binding protein H 2.16815
DRC11 dynein regulatory complex subunit 11 2.16783
NUCB1 nucleobindin 1 2.16727
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.16708
PCGF1 polycomb group ring finger 1 2.16516
MTFR1 mitochondrial fission regulator 1 2.1638
VSX1 visual system homeobox 1 2.16226
KIAA0930 KIAA0930 2.16221
LRRC49 leucine rich repeat containing 49 2.16207
TBX6 T-box 6 2.15858
APOL5 apolipoprotein L, 5 2.15778
LHCGR luteinizing hormone/choriogonadotropin receptor 2.15745
HNF4G hepatocyte nuclear factor 4, gamma 2.15704
MTNR1A melatonin receptor 1A 2.15566
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7 2.15535
SLC17A4 solute carrier family 17, member 4 2.15457
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 2.15419
TLN2 talin 2 2.15245
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 2.15152
GJB5 gap junction protein, beta 5, 31.1kDa 2.15038
CD200R1 CD200 receptor 1 2.14962
SIRT6 sirtuin 6 2.14903
FKBP4 FK506 binding protein 4, 59kDa 2.14866
NDRG1 N-myc downstream regulated 1 2.1484
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 2.14689
ESRP1 epithelial splicing regulatory protein 1 2.146
POU5F1 POU class 5 homeobox 1 2.14559
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 2.14463
LHX3 LIM homeobox 3 2.14258
GJA4 gap junction protein, alpha 4, 37kDa 2.14157
FOXL2 forkhead box L2 2.13969
GDAP2 ganglioside induced differentiation associated protein 2 2.13682
PCDHB11 protocadherin beta 11 2.13571
CLEC5A C-type lectin domain family 5, member A 2.13499
ZNF34 zinc finger protein 34 2.13191
GFRA4 GDNF family receptor alpha 4 2.13109
LIN37 lin-37 DREAM MuvB core complex component 2.13036
ZNF235 zinc finger protein 235 2.12916
CRYZL1 crystallin, zeta (quinone reductase)-like 1 2.12812
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 2.12463
STYK1 serine/threonine/tyrosine kinase 1 2.12302
DGKA diacylglycerol kinase, alpha 80kDa 2.12171
EML2 echinoderm microtubule associated protein like 2 2.12068
TAS2R4 taste receptor, type 2, member 4 2.11941
DOC2B double C2-like domains, beta 2.11912
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 2.11868
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 2.1177
PRKG1 protein kinase, cGMP-dependent, type I 2.1124
MED25 mediator complex subunit 25 2.11226
ASXL3 additional sex combs like transcriptional regulator 3 2.11203
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 2.11163
IRF6 interferon regulatory factor 6 2.10964
UNC5B unc-5 homolog B (C. elegans) 2.10682
ADGRG1 adhesion G protein-coupled receptor G1 2.10682
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) 2.10626
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 2.10431
FETUB fetuin B 2.10416
RAP2A RAP2A, member of RAS oncogene family 2.10294
GALNT8 polypeptide N-acetylgalactosaminyltransferase 8 2.10204
EPHX2 epoxide hydrolase 2, cytoplasmic 2.1004
SBDS Shwachman-Bodian-Diamond syndrome 2.0999
CLCA1 chloride channel accessory 1 2.09832
PLCH2 phospholipase C, eta 2 2.09494
SCRT1 scratch family zinc finger 1 2.09489
DNAI4 dynein axonemal intermediate chain 4 2.09396
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 2.09093
DGKB diacylglycerol kinase, beta 90kDa 2.09041
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 2.09005
EMX1 empty spiracles homeobox 1 2.08951
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 2.0882
AMBN ameloblastin (enamel matrix protein) 2.0869
ELAVL4 ELAV like neuron-specific RNA binding protein 4 2.08672
FRMD4A FERM domain containing 4A 2.08626
L1TD1 LINE-1 type transposase domain containing 1 2.08512
OR3A3 olfactory receptor, family 3, subfamily A, member 3 2.08454
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 2.08374
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 2.08193
MMRN2 multimerin 2 2.07757
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 2.07715
HOXC5 homeobox C5 2.07606
CYSLTR1 cysteinyl leukotriene receptor 1 2.07572
ACSM2A acyl-CoA synthetase medium-chain family member 2A 2.0736
VAV3 vav 3 guanine nucleotide exchange factor 2.07343
ZNF33B zinc finger protein 33B 2.07148
QPCTL glutaminyl-peptide cyclotransferase-like 2.06408
AKT3 v-akt murine thymoma viral oncogene homolog 3 2.06383
DAGLA diacylglycerol lipase, alpha 2.06252
TRIM10 tripartite motif containing 10 2.06197
NOP53 NOP53 ribosome biogenesis factor 2.06167
MYOZ3 myozenin 3 2.06045
ZNF74 zinc finger protein 74 2.05974
H2BC21 H2B clustered histone 21 2.05831
DOC2A double C2-like domains, alpha 2.05726
SUSD4 sushi domain containing 4 2.05461
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) 2.05413
CD44 CD44 molecule (Indian blood group) 2.05236
TFDP3 transcription factor Dp family, member 3 2.04886
ZBTB7C zinc finger and BTB domain containing 7C 2.04877
TMEM35A transmembrane protein 35A 2.04773
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.04773
RDH16 retinol dehydrogenase 16 (all-trans) 2.04755
BACE2 beta-site APP-cleaving enzyme 2 2.04675
PDE1B phosphodiesterase 1B, calmodulin-dependent 2.04526
SCRN1 secernin 1 2.04493
ZFAND1 zinc finger, AN1-type domain 1 2.04472
OR3A1 olfactory receptor, family 3, subfamily A, member 1 2.04436
ZIM3 zinc finger, imprinted 3 2.04425
H1-3 H1.3 linker histone, cluster member 2.0442
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 2.04416
POLR1B polymerase (RNA) I polypeptide B, 128kDa 2.04089
CUX2 cut-like homeobox 2 2.03902
TDP2 tyrosyl-DNA phosphodiesterase 2 2.03717
UNC13A unc-13 homolog A (C. elegans) 2.03681
SNAP29 synaptosomal-associated protein, 29kDa 2.03632
H1-2 H1.2 linker histone, cluster member 2.03631
MYCT1 myc target 1 2.03474
HOXA3 homeobox A3 2.03424
COQ8B coenzyme Q8B 2.03411
FJX1 four jointed box 1 (Drosophila) 2.03292
LARP6 La ribonucleoprotein domain family, member 6 2.03226
UPK2 uroplakin 2 2.03111
SPINK4 serine peptidase inhibitor, Kazal type 4 2.03093
POU4F3 POU class 4 homeobox 3 2.03038
RGS16 regulator of G-protein signaling 16 2.02736
ZBTB5 zinc finger and BTB domain containing 5 2.02673
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 2.0253
BAX BCL2-associated X protein 2.02486
PLAAT2 phospholipase A and acyltransferase 2 2.02374
STXBP2 syntaxin binding protein 2 2.02337
NPFFR1 neuropeptide FF receptor 1 2.02072
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 2.01984
CYTH2 cytohesin 2 2.01472
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 2.01469
AMH anti-Mullerian hormone 2.0137
MMP24OS MMP24 opposite strand 2.01184
PEX6 peroxisomal biogenesis factor 6 2.01153
WASHC5 WASH complex subunit 5 2.0104
TBC1D8B TBC1 domain family, member 8B (with GRAM domain) 2.01024
ZNF322 zinc finger protein 322 2.00975
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 2.00943
CEP57 centrosomal protein 57kDa 2.00787
ZIC3 Zic family member 3 2.00748
E2F2 E2F transcription factor 2 2.00662
ZNF277 zinc finger protein 277 2.00617
GPATCH2L G patch domain containing 2-like 2.00518
RFPL3 ret finger protein-like 3 2.00404
RBM8A RNA binding motif protein 8A 2.00134
HOXB1 homeobox B1 2.0012

decreased expression

Symbol Name Standardized Value
FASTKD5 FAST kinase domains 5 -8.28041
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -8.11624
CASP3 caspase 3, apoptosis-related cysteine peptidase -7.28854
PCCB propionyl CoA carboxylase, beta polypeptide -6.47545
CD58 CD58 molecule -6.31631
HAT1 histone acetyltransferase 1 -6.17182
UBE3C ubiquitin protein ligase E3C -6.07609
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -5.93087
ANKRD10 ankyrin repeat domain 10 -5.88504
GRWD1 glutamate-rich WD repeat containing 1 -5.51582
GNAS GNAS complex locus -5.44118
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -5.32031
ARFIP2 ADP-ribosylation factor interacting protein 2 -5.2929
CASP7 caspase 7, apoptosis-related cysteine peptidase -4.93469
TLCD3A TLC domain containing 3A -4.82945
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -4.77354
CHMP4B charged multivesicular body protein 4B -4.76964
ETFB electron-transfer-flavoprotein, beta polypeptide -4.70113
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -4.58208
GLOD4 glyoxalase domain containing 4 -4.50455
VAT1 vesicle amine transport 1 -4.45967
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.43141
PCNA proliferating cell nuclear antigen -4.43129
TSKU tsukushi, small leucine rich proteoglycan -4.34381
ENOPH1 enolase-phosphatase 1 -4.33935
TXNRD1 thioredoxin reductase 1 -4.23542
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.13633
NNT nicotinamide nucleotide transhydrogenase -4.13504
KDM3A lysine (K)-specific demethylase 3A -4.09293
LDHD lactate dehydrogenase D -4.07054
MYC v-myc avian myelocytomatosis viral oncogene homolog -3.94418
TCERG1 transcription elongation regulator 1 -3.84038
GET1 guided entry of tail-anchored proteins factor 1 -3.81592
DCK deoxycytidine kinase -3.76499
SLC35F2 solute carrier family 35, member F2 -3.73863
BCL7B B-cell CLL/lymphoma 7B -3.59274
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.58421
NT5DC2 5'-nucleotidase domain containing 2 -3.55806
ACOT9 acyl-CoA thioesterase 9 -3.54563
TLR4 toll-like receptor 4 -3.44679
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -3.44602
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.44492
EED embryonic ectoderm development -3.41202
PGM1 phosphoglucomutase 1 -3.37877
KLHL21 kelch-like family member 21 -3.35908
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor -3.34619
ISOC1 isochorismatase domain containing 1 -3.30441
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -3.28121
CAPN7 calpain 7 -3.2691
CARMIL1 capping protein regulator and myosin 1 linker 1 -3.26855
CDC25B cell division cycle 25B -3.23284
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.22465
MAPK13 mitogen-activated protein kinase 13 -3.21004
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.20989
GALE UDP-galactose-4-epimerase -3.20119
CDK6 cyclin-dependent kinase 6 -3.19496
CIRBP cold inducible RNA binding protein -3.18322
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -3.12714
STAT1 signal transducer and activator of transcription 1, 91kDa -3.10124
IQGAP2 IQ motif containing GTPase activating protein 2 -3.0924
ODAM odontogenic, ameloblast asssociated -3.05755
ANKRD17 ankyrin repeat domain 17 -3.04343
CDK1 cyclin-dependent kinase 1 -3.03223
COG7 component of oligomeric golgi complex 7 -3.01018
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.93181
STK25 serine/threonine kinase 25 -2.92255
IDE insulin-degrading enzyme -2.91515
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 -2.90381
TATDN2 TatD DNase domain containing 2 -2.89847
OTUD3 OTU deubiquitinase 3 -2.89551
DCPS decapping enzyme, scavenger -2.88248
BLCAP bladder cancer associated protein -2.8493
DENND5A DENN/MADD domain containing 5A -2.84913
SOAT1 sterol O-acyltransferase 1 -2.84161
CCNA2 cyclin A2 -2.84073
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -2.84068
CCNB2 cyclin B2 -2.82925
ERH enhancer of rudimentary homolog (Drosophila) -2.77825
SEC23A Sec23 homolog A (S. cerevisiae) -2.73636
UFM1 ubiquitin-fold modifier 1 -2.73015
TMEM109 transmembrane protein 109 -2.71111
MARCHF7 membrane associated ring-CH-type finger 7 -2.70934
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.7066
MBNL3 muscleblind-like splicing regulator 3 -2.7064
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -2.68853
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) -2.68767
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.68481
CASC3 cancer susceptibility candidate 3 -2.67889
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.66639
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') -2.66035
NCK1 NCK adaptor protein 1 -2.65587
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -2.64515
LGMN legumain -2.62496
SELENOF selenoprotein F -2.6236
KYNU kynureninase -2.61834
PRSS23 protease, serine, 23 -2.61726
CHPT1 choline phosphotransferase 1 -2.60933
PRPF4 pre-mRNA processing factor 4 -2.60137
CHI3L2 chitinase 3-like 2 -2.5802
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.57145
FRS2 fibroblast growth factor receptor substrate 2 -2.56308
TRAPPC4 trafficking protein particle complex 4 -2.55964
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 -2.55849
RGS2 regulator of G-protein signaling 2 -2.55458
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.55155
TCTN1 tectonic family member 1 -2.53859
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -2.53565
PRDX1 peroxiredoxin 1 -2.52772
FGFR4 fibroblast growth factor receptor 4 -2.51575
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -2.51023
CRYZ crystallin, zeta (quinone reductase) -2.50213
ANXA7 annexin A7 -2.4969
PRPF39 pre-mRNA processing factor 39 -2.49487
NRBF2 nuclear receptor binding factor 2 -2.49254
IGFBP1 insulin-like growth factor binding protein 1 -2.48909
ADAM10 ADAM metallopeptidase domain 10 -2.48445
RRAGA Ras-related GTP binding A -2.46939
HACD1 3-hydroxyacyl-CoA dehydratase 1 -2.459
WDR7 WD repeat domain 7 -2.45841
SUB1 SUB1 homolog (S. cerevisiae) -2.45211
NCK2 NCK adaptor protein 2 -2.44702
GTF2A2 general transcription factor IIA, 2, 12kDa -2.44398
MELK maternal embryonic leucine zipper kinase -2.43971
BLTP3B bridge-like lipid transfer protein family member 3B -2.43875
DKK1 dickkopf WNT signaling pathway inhibitor 1 -2.43779
CTTN cortactin -2.4296
SELL selectin L -2.42867
CHMP6 charged multivesicular body protein 6 -2.42353
CCNE1 cyclin E1 -2.42231
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) -2.42214
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.41715
PRMT3 protein arginine methyltransferase 3 -2.41451
LBR lamin B receptor -2.41037
AFG3L2 AFG3-like AAA ATPase 2 -2.40573
RFC2 replication factor C (activator 1) 2, 40kDa -2.39484
SKIC2 SKI2 subunit of superkiller complex -2.3932
ZBTB35 zinc finger and BTB domain containing 35 -2.38898
TMX1 thioredoxin-related transmembrane protein 1 -2.38309
SEC23IP SEC23 interacting protein -2.37658
RBM14-RBM4 RBM14-RBM4 readthrough -2.36754
C1S complement component 1, s subcomponent -2.36459
TBC1D31 TBC1 domain family, member 31 -2.35665
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -2.34202
ADO 2-aminoethanethiol (cysteamine) dioxygenase -2.33705
AKAP11 A kinase (PRKA) anchor protein 11 -2.33551
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -2.33423
CMC2 C-x(9)-C motif containing 2 -2.33112
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 -2.32846
TOM1 target of myb1 (chicken) -2.32226
NFIL3 nuclear factor, interleukin 3 regulated -2.32165
TM9SF3 transmembrane 9 superfamily member 3 -2.32125
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -2.31562
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase -2.3125
TRAPPC3 trafficking protein particle complex 3 -2.31185
UBE2D1 ubiquitin-conjugating enzyme E2D 1 -2.30862
TACC3 transforming, acidic coiled-coil containing protein 3 -2.30401
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 -2.30346
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 -2.30316
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 -2.29894
SRRD SRR1 domain containing -2.29571
TRIB1 tribbles pseudokinase 1 -2.27927
DOLK dolichol kinase -2.27249
KRT10 keratin 10, type I -2.27216
HPS5 Hermansky-Pudlak syndrome 5 -2.2626
NOP56 NOP56 ribonucleoprotein -2.26023
BECN1 beclin 1, autophagy related -2.25598
KDM1A lysine (K)-specific demethylase 1A -2.25378
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 -2.25032
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -2.24781
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -2.24683
REEP5 receptor accessory protein 5 -2.24672
BST2 bone marrow stromal cell antigen 2 -2.2454
SBNO1 strawberry notch homolog 1 (Drosophila) -2.23807
UBE4A ubiquitination factor E4A -2.23257
AGMAT agmatine ureohydrolase (agmatinase) -2.23097
ZDHHC6 zinc finger, DHHC-type containing 6 -2.22873
ICAM3 intercellular adhesion molecule 3 -2.22673
GAA glucosidase, alpha; acid -2.21934
TBX2 T-box 2 -2.21743
SLC31A1 solute carrier family 31 (copper transporter), member 1 -2.21657
UBP1 upstream binding protein 1 (LBP-1a) -2.21551
NUP98 nucleoporin 98kDa -2.21531
ZDHHC18 zinc finger, DHHC-type containing 18 -2.21452
COQ10B coenzyme Q10 homolog B (S. cerevisiae) -2.21232
ACAA1 acetyl-CoA acyltransferase 1 -2.20141
MRPS16 mitochondrial ribosomal protein S16 -2.19965
CD151 CD151 molecule (Raph blood group) -2.19808
NISCH nischarin -2.19157
PMF1-BGLAP PMF1-BGLAP readthrough -2.19085
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.18511
CST3 cystatin C -2.18262
CPVL carboxypeptidase, vitellogenic-like -2.1768
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa -2.17235
CLTC clathrin, heavy chain (Hc) -2.17022
TMEM185B transmembrane protein 185B -2.16854
SRSF9 serine/arginine-rich splicing factor 9 -2.1665
LSR lipolysis stimulated lipoprotein receptor -2.16369
MLEC malectin -2.15852
SEPTIN8 septin 8 -2.15555
SRP54 signal recognition particle 54kDa -2.15053
PCF11 PCF11 cleavage and polyadenylation factor subunit -2.15023
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.1465
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -2.14488
SSUH2 ssu-2 homolog (C. elegans) -2.13146
PDIA5 protein disulfide isomerase family A, member 5 -2.12811
TDG thymine-DNA glycosylase -2.1253
BCAS3 breast carcinoma amplified sequence 3 -2.12012
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -2.11912
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -2.11833
AMDHD2 amidohydrolase domain containing 2 -2.11695
PMPCA peptidase (mitochondrial processing) alpha -2.11123
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -2.11122
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.10593
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.10575
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -2.10502
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase -2.09857
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) -2.09716
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa -2.09608
WDR1 WD repeat domain 1 -2.09064
TOMM70 translocase of outer mitochondrial membrane 70 -2.0902
HSPE1 heat shock 10kDa protein 1 -2.07818
SEC16A SEC16 homolog A (S. cerevisiae) -2.07767
PLAGL2 pleiomorphic adenoma gene-like 2 -2.07642
MARCKSL1 MARCKS-like 1 -2.06953
TTC4 tetratricopeptide repeat domain 4 -2.06263
IGFLR1 IGF-like family receptor 1 -2.06187
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -2.05595
CST2 cystatin SA -2.05246
AAR2 AAR2 splicing factor homolog (S. cerevisiae) -2.04905
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -2.04745
SMC1A structural maintenance of chromosomes 1A -2.04196
RSU1 Ras suppressor protein 1 -2.04031
ZCCHC24 zinc finger, CCHC domain containing 24 -2.03886
MPPE1 metallophosphoesterase 1 -2.03757
IER3 immediate early response 3 -2.02674
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -2.02412
MRGBP MRG/MORF4L binding protein -2.01921
RCC1L RCC1 like -2.0177
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -2.01713
TOR1AIP1 torsin A interacting protein 1 -2.01579
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 -2.01283
GSTM3 glutathione S-transferase mu 3 (brain) -2.01019
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.00766
ASXL1 additional sex combs like transcriptional regulator 1 -2.00665
PANK2 pantothenate kinase 2 -2.0029
DYNLL1 dynein, light chain, LC8-type 1 -2.0022
PIPOX pipecolic acid oxidase -2.00161