CRCGN014_HEPG2_3H:L22 Gene Set
Genes
43 genes differentially expressed following the CRCGN014_HEPG2_3H:L22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
7.67532
|
|
PRR15L
|
proline rich 15-like
|
4.98024
|
|
CHN1
|
chimerin 1
|
4.62716
|
|
CCNF
|
cyclin F
|
3.83416
|
|
JADE2
|
jade family PHD finger 2
|
3.40625
|
|
CSK
|
c-src tyrosine kinase
|
3.24054
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
3.2047
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.81875
|
|
PCDHB11
|
protocadherin beta 11
|
2.72432
|
|
KLHL9
|
kelch-like family member 9
|
2.50139
|
|
MYLK
|
myosin light chain kinase
|
2.46039
|
|
RAP1GAP
|
RAP1 GTPase activating protein
|
2.45024
|
|
HEBP1
|
heme binding protein 1
|
2.40994
|
|
CCDC86
|
coiled-coil domain containing 86
|
2.40429
|
|
NAT9
|
N-acetyltransferase 9 (GCN5-related, putative)
|
2.39094
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.30883
|
|
UBR7
|
ubiquitin protein ligase E3 component n-recognin 7 (putative)
|
2.30651
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.21406
|
|
ZNF589
|
zinc finger protein 589
|
2.09025
|
|
SIRT3
|
sirtuin 3
|
2.07324
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.07156
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.05603
|
|
USP6NL
|
USP6 N-terminal like
|
2.04316
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-9.26698
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.84157
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-6.23435
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.86994
|
|
COG7
|
component of oligomeric golgi complex 7
|
-4.78131
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.53283
|
|
GNAS
|
GNAS complex locus
|
-3.93388
|
|
CTSD
|
cathepsin D
|
-3.3125
|
|
ZNF586
|
zinc finger protein 586
|
-3.08502
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.76197
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.74246
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.67264
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.62049
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.58432
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.49543
|
|
PGM1
|
phosphoglucomutase 1
|
-2.37509
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.13677
|
|
MIER2
|
mesoderm induction early response 1, family member 2
|
-2.11276
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
-2.08428
|
|
ZNF142
|
zinc finger protein 142
|
-2.08164
|
