CRCGN014_HEPG2_3H:L24 Gene Set
Genes
60 genes differentially expressed following the CRCGN014_HEPG2_3H:L24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STK10
|
serine/threonine kinase 10
|
7.23428
|
|
MYLK
|
myosin light chain kinase
|
6.43187
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.1922
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
6.17998
|
|
PMM2
|
phosphomannomutase 2
|
4.67807
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.92601
|
|
UBQLN2
|
ubiquilin 2
|
3.47419
|
|
PRR15L
|
proline rich 15-like
|
3.32266
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.20268
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
3.02713
|
|
TEX10
|
testis expressed 10
|
2.89196
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.67244
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.5309
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.51406
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.51021
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.47696
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.46566
|
|
CCNF
|
cyclin F
|
2.39502
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.35772
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.21668
|
|
EXOSC4
|
exosome component 4
|
2.20818
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.20557
|
|
KIF20A
|
kinesin family member 20A
|
2.17421
|
|
NBEAL2
|
neurobeachin-like 2
|
2.17108
|
|
LOC100533997
|
MAGEA10-MAGEA5 readthrough
|
2.14598
|
|
MAGEA1
|
melanoma antigen family A1
|
2.12396
|
|
CHN1
|
chimerin 1
|
2.11707
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.09143
|
|
ETNK2
|
ethanolamine kinase 2
|
2.08566
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.07008
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-7.09764
|
|
CCNB2
|
cyclin B2
|
-6.38382
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-5.6877
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.88229
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-3.7087
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-3.55916
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.38727
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.04947
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.95004
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.71827
|
|
ICAM3
|
intercellular adhesion molecule 3
|
-2.59695
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.58471
|
|
TBCB
|
tubulin folding cofactor B
|
-2.56297
|
|
ZNF586
|
zinc finger protein 586
|
-2.51131
|
|
COX6B1
|
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
|
-2.48362
|
|
DBNDD2
|
dysbindin (dystrobrevin binding protein 1) domain containing 2
|
-2.3731
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.36082
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.35677
|
|
WASHC4
|
WASH complex subunit 4
|
-2.34445
|
|
ZNF146
|
zinc finger protein 146
|
-2.33444
|
|
SNX11
|
sorting nexin 11
|
-2.33372
|
|
SDHAF1
|
succinate dehydrogenase complex assembly factor 1
|
-2.26766
|
|
NVL
|
nuclear VCP-like
|
-2.2225
|
|
PSMD8
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
|
-2.16624
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.10736
|
|
GPATCH1
|
G patch domain containing 1
|
-2.10603
|
|
CKS1B
|
CDC28 protein kinase regulatory subunit 1B
|
-2.09189
|
|
BRD7
|
bromodomain containing 7
|
-2.05992
|
|
RBM42
|
RNA binding motif protein 42
|
-2.05307
|
|
LTC4S
|
leukotriene C4 synthase
|
-2.02241
|
