CRCGN014_HEPG2_3H:M03 Gene Set
Genes
50 genes differentially expressed following the CRCGN014_HEPG2_3H:M03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAMLD1
|
mastermind-like domain containing 1
|
3.70146
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.65759
|
|
CBR3
|
carbonyl reductase 3
|
3.33496
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.28065
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.22845
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.00183
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.74484
|
|
CTSL
|
cathepsin L
|
2.67199
|
|
CRTAP
|
cartilage associated protein
|
2.58579
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.57473
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.54492
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.37128
|
|
MAP7
|
microtubule-associated protein 7
|
2.27328
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.24087
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.21965
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
2.18146
|
|
BAALC
|
brain and acute leukemia, cytoplasmic
|
2.16081
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.14722
|
|
CLOCK
|
clock circadian regulator
|
2.06063
|
|
ABCG5
|
ATP-binding cassette, sub-family G (WHITE), member 5
|
2.05581
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.02562
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-10.0
|
|
VAT1
|
vesicle amine transport 1
|
-6.56802
|
|
DNM1L
|
dynamin 1-like
|
-6.56769
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.28526
|
|
LDHD
|
lactate dehydrogenase D
|
-6.20698
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.45749
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.93112
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.78323
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.33109
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.96808
|
|
HMG20B
|
high mobility group 20B
|
-2.92277
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.86311
|
|
CDC20
|
cell division cycle 20
|
-2.85265
|
|
CDC25B
|
cell division cycle 25B
|
-2.78345
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.73599
|
|
ZNF586
|
zinc finger protein 586
|
-2.67052
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.62888
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.59575
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.52293
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.50449
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.32103
|
|
CHEK1
|
checkpoint kinase 1
|
-2.31773
|
|
TLR4
|
toll-like receptor 4
|
-2.30147
|
|
NSFL1C
|
NSFL1 (p97) cofactor (p47)
|
-2.25986
|
|
MS4A3
|
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
|
-2.15278
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.09637
|
|
ARID3A
|
AT rich interactive domain 3A (BRIGHT-like)
|
-2.09568
|
|
ALKBH1
|
alkB, alkylation repair homolog 1 (E. coli)
|
-2.03432
|
|
OVOL2
|
ovo-like zinc finger 2
|
-2.00897
|
