CRCGN014_HEPG2_3H:M04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description furan 38.0 um perturbation at 3 h in HEPG2 (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN014_HEPG2_3H:M04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.62316
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 4.55299
CBR3 carbonyl reductase 3 4.22921
DIPK1A divergent protein kinase domain 1A 4.00634
EPN2 epsin 2 3.49032
KIF14 kinesin family member 14 3.39767
STIMATE STIM activating enhancer 3.29427
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.8774
TIAM1 T-cell lymphoma invasion and metastasis 1 2.48571
TSPAN6 tetraspanin 6 2.29782
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.23276
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.18344

decreased expression

Symbol Name Standardized Value
ZNF586 zinc finger protein 586 -8.64707
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -6.46503
LDHD lactate dehydrogenase D -5.34388
ZMIZ1 zinc finger, MIZ-type containing 1 -4.50182
ARID5B AT rich interactive domain 5B (MRF1-like) -4.33493
NT5DC2 5'-nucleotidase domain containing 2 -4.15704
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.02545
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -3.26028
OXA1L oxidase (cytochrome c) assembly 1-like -3.0188
GNAS GNAS complex locus -2.94652
TLR4 toll-like receptor 4 -2.86398
HMG20B high mobility group 20B -2.41654
LOC124907782 dual specificity protein phosphatase 22 -2.17666