| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | barium chloride dihydrate 40.4 um perturbation at 3 h in HEPG2 (Carcinogenome) |
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60 genes differentially expressed following the CRCGN014_HEPG2_3H:M05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 6.6923 |
| MAP7 | microtubule-associated protein 7 | 4.59766 |
| LCN2 | lipocalin 2 | 3.74687 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.3983 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 3.39527 |
| CBR3 | carbonyl reductase 3 | 3.38067 |
| CHMP6 | charged multivesicular body protein 6 | 3.30313 |
| ADRB2 | adrenoceptor beta 2, surface | 3.18527 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.07183 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.06797 |
| FZD7 | frizzled class receptor 7 | 3.06243 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.83488 |
| NOSIP | nitric oxide synthase interacting protein | 2.82553 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.80437 |
| EPHB2 | EPH receptor B2 | 2.63348 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | 2.61005 |
| UBE2A | ubiquitin-conjugating enzyme E2A | 2.51952 |
| UBQLN2 | ubiquilin 2 | 2.4804 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 2.45917 |
| MEST | mesoderm specific transcript | 2.4543 |
| ATP11B | ATPase, class VI, type 11B | 2.39837 |
| KIF20A | kinesin family member 20A | 2.36273 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.31387 |
| TLK2 | tousled-like kinase 2 | 2.27995 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.27545 |
| CHRND | cholinergic receptor, nicotinic, delta (muscle) | 2.1963 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | 2.16893 |
| TBP | TATA box binding protein | 2.16393 |
| CHODL | chondrolectin | 2.13993 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.1384 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.0846 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.06637 |
| TXNL4B | thioredoxin-like 4B | 2.0266 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -6.24703 |
| SPAG4 | sperm associated antigen 4 | -3.8671 |
| CCDC86 | coiled-coil domain containing 86 | -3.82167 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.73827 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.58173 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.352 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.33333 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.3331 |
| PCNA | proliferating cell nuclear antigen | -3.23147 |
| TMCO1 | transmembrane and coiled-coil domains 1 | -2.98994 |
| LDHD | lactate dehydrogenase D | -2.94317 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -2.83967 |
| CCNB1 | cyclin B1 | -2.76497 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.7233 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.61938 |
| NGRN | neugrin, neurite outgrowth associated | -2.581 |
| CDC20 | cell division cycle 20 | -2.5347 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.46863 |
| CSK | c-src tyrosine kinase | -2.3886 |
| TLCD3A | TLC domain containing 3A | -2.3759 |
| CCNH | cyclin H | -2.33753 |
| TXNDC9 | thioredoxin domain containing 9 | -2.30687 |
| WDR7 | WD repeat domain 7 | -2.22383 |
| SNX11 | sorting nexin 11 | -2.1437 |
| GLOD4 | glyoxalase domain containing 4 | -2.13763 |
| TCTN1 | tectonic family member 1 | -2.1124 |
| MTA1 | metastasis associated 1 | -2.00077 |