| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | carbon-tetrachloride 39.4 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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77 genes differentially expressed following the CRCGN014_HEPG2_3H:M06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 7.92683 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.98066 |
| STIMATE | STIM activating enhancer | 4.79735 |
| EAPP | E2F-associated phosphoprotein | 4.71101 |
| CSK | c-src tyrosine kinase | 4.66849 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.65837 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.6209 |
| BZW2 | basic leucine zipper and W2 domains 2 | 4.58035 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 4.57625 |
| DENND2D | DENN/MADD domain containing 2D | 4.38478 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.32314 |
| EVL | Enah/Vasp-like | 4.14024 |
| ADRB2 | adrenoceptor beta 2, surface | 4.01088 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.5936 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.58799 |
| PFKL | phosphofructokinase, liver | 3.30115 |
| SLC25A46 | solute carrier family 25, member 46 | 3.24386 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 3.16801 |
| TXNL4B | thioredoxin-like 4B | 3.07948 |
| JADE2 | jade family PHD finger 2 | 2.97273 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.87555 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.58239 |
| KIF14 | kinesin family member 14 | 2.56667 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.55819 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.50523 |
| SLC75A1 | solute carrier family 75 member 1 | 2.46334 |
| CDC45 | cell division cycle 45 | 2.44393 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.42103 |
| GRB2 | growth factor receptor-bound protein 2 | 2.40938 |
| TAOK1 | TAO kinase 1 | 2.34627 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.34264 |
| SFTPB | surfactant protein B | 2.31564 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 | 2.29821 |
| TRAM2 | translocation associated membrane protein 2 | 2.23103 |
| HAUS2 | HAUS augmin-like complex, subunit 2 | 2.21264 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | 2.17136 |
| HOXC4 | homeobox C4 | 2.14613 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | 2.13463 |
| ALS2CL | ALS2 C-terminal like | 2.02548 |
| XAF1 | XIAP associated factor 1 | 2.015 |
| VASP | vasodilator-stimulated phosphoprotein | 2.01388 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -9.19948 |
| LDHD | lactate dehydrogenase D | -8.94172 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -5.98077 |
| UGDH | UDP-glucose 6-dehydrogenase | -4.65966 |
| ADI1 | acireductone dioxygenase 1 | -4.62083 |
| ENOPH1 | enolase-phosphatase 1 | -4.40919 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -4.04925 |
| GNAS | GNAS complex locus | -3.96935 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -3.8375 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -3.58279 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.43859 |
| MTA1 | metastasis associated 1 | -2.95643 |
| SLC35F2 | solute carrier family 35, member F2 | -2.88688 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -2.80547 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -2.67319 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.53877 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.49198 |
| KLHDC4 | kelch domain containing 4 | -2.49024 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -2.4472 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -2.38382 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.32469 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | -2.30972 |
| SPAG4 | sperm associated antigen 4 | -2.26443 |
| ADAM9 | ADAM metallopeptidase domain 9 | -2.2222 |
| EPCAM | epithelial cell adhesion molecule | -2.21915 |
| SPARCL1 | SPARC-like 1 (hevin) | -2.18994 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.1081 |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) | -2.10518 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.08833 |
| PGAM2 | phosphoglycerate mutase 2 (muscle) | -2.07188 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | -2.06804 |
| S1PR5 | sphingosine-1-phosphate receptor 5 | -2.04744 |
| PODXL | podocalyxin-like | -2.04261 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 | -2.01814 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.01739 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | -2.00511 |
