CRCGN014_HEPG2_3H:M09 Gene Set
Genes
48 genes differentially expressed following the CRCGN014_HEPG2_3H:M09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
10.0
|
|
HOXA10
|
homeobox A10
|
4.52655
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.17271
|
|
PRR15L
|
proline rich 15-like
|
4.09796
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.88063
|
|
UBQLN2
|
ubiquilin 2
|
3.87453
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.41701
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.36362
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.34758
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
2.99041
|
|
SATB1
|
SATB homeobox 1
|
2.95683
|
|
CYCS
|
cytochrome c, somatic
|
2.84773
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.79685
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.74781
|
|
HOXA10-HOXA9
|
HOXA10-HOXA9 readthrough
|
2.63285
|
|
SQOR
|
sulfide quinone oxidoreductase
|
2.61271
|
|
KIF20A
|
kinesin family member 20A
|
2.57439
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.52621
|
|
HEBP1
|
heme binding protein 1
|
2.47421
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.39935
|
|
ERO1A
|
endoplasmic reticulum oxidoreductase 1 alpha
|
2.35285
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.31135
|
|
RAB4A
|
RAB4A, member RAS oncogene family
|
2.24583
|
|
PNPLA3
|
patatin-like phospholipase domain containing 3
|
2.02823
|
|
UBE2A
|
ubiquitin-conjugating enzyme E2A
|
2.01461
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-5.7909
|
|
CCNB2
|
cyclin B2
|
-5.21963
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.92362
|
|
VAT1
|
vesicle amine transport 1
|
-4.13394
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.08255
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-3.98801
|
|
CCNB1
|
cyclin B1
|
-3.88625
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.63189
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-3.62073
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-3.53356
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.44493
|
|
TLR4
|
toll-like receptor 4
|
-3.27507
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-3.23602
|
|
ZNF586
|
zinc finger protein 586
|
-3.21135
|
|
LDHD
|
lactate dehydrogenase D
|
-3.19809
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.87927
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.61649
|
|
SCAND1
|
SCAN domain containing 1
|
-2.52051
|
|
TCEAL4
|
transcription elongation factor A (SII)-like 4
|
-2.35047
|
|
TMEM147
|
transmembrane protein 147
|
-2.28514
|
|
LHFPL2
|
lipoma HMGIC fusion partner-like 2
|
-2.12179
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.0416
|
|
SRD5A1
|
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
|
-2.03755
|
