CRCGN014_HEPG2_3H:M11 Gene Set
Genes
40 genes differentially expressed following the CRCGN014_HEPG2_3H:M11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
6.36858
|
|
STAP2
|
signal transducing adaptor family member 2
|
3.84498
|
|
NOTCH1
|
notch 1
|
3.31791
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.18298
|
|
CBR3
|
carbonyl reductase 3
|
2.977
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.95547
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.85853
|
|
FZD7
|
frizzled class receptor 7
|
2.77569
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
2.77539
|
|
CRTAP
|
cartilage associated protein
|
2.74875
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
2.70275
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.62938
|
|
STIMATE
|
STIM activating enhancer
|
2.55837
|
|
STK10
|
serine/threonine kinase 10
|
2.47007
|
|
SCYL3
|
SCY1-like 3 (S. cerevisiae)
|
2.43531
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.38902
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.26249
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.10995
|
|
TBXA2R
|
thromboxane A2 receptor
|
2.09692
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
2.07762
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.0158
|
|
GPATCH8
|
G patch domain containing 8
|
2.00132
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-5.84916
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.96785
|
|
LDHD
|
lactate dehydrogenase D
|
-3.75862
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.53135
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.3343
|
|
TLR4
|
toll-like receptor 4
|
-3.31327
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.24407
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-2.86427
|
|
NLRP2B
|
NLR family pyrin domain containing 2B
|
-2.80416
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.70576
|
|
DNM1L
|
dynamin 1-like
|
-2.3247
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.31307
|
|
ZNF586
|
zinc finger protein 586
|
-2.18346
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.15597
|
|
GDF15
|
growth differentiation factor 15
|
-2.15394
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.13533
|
|
ECT2
|
epithelial cell transforming 2
|
-2.10493
|
|
MMP3
|
matrix metallopeptidase 3
|
-2.00754
|
