CRCGN014_HEPG2_3H:M12 Gene Set
Genes
40 genes differentially expressed following the CRCGN014_HEPG2_3H:M12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
7.10795
|
|
CHN1
|
chimerin 1
|
5.0989
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.67861
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.59042
|
|
ZNF589
|
zinc finger protein 589
|
3.35618
|
|
MYLK
|
myosin light chain kinase
|
3.35401
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.33847
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.16176
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.9552
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.65569
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.48468
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.3796
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.26231
|
|
PRKCH
|
protein kinase C, eta
|
2.19009
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.15795
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.13503
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.12438
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.11356
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-6.10376
|
|
LDHD
|
lactate dehydrogenase D
|
-6.03124
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.97796
|
|
CCNB2
|
cyclin B2
|
-5.05253
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.9256
|
|
VAT1
|
vesicle amine transport 1
|
-3.63401
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.08203
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.95277
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.81228
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.72617
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
-2.66583
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.63215
|
|
GNAS
|
GNAS complex locus
|
-2.44532
|
|
CPNE3
|
copine III
|
-2.42472
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.41084
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.36121
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.25892
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.19105
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.11285
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.09112
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-2.0494
|
|
EIF4A3
|
eukaryotic translation initiation factor 4A3
|
-2.04707
|
