CRCGN014_HEPG2_3H:M13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ampicillin 34.0 um perturbation at 3 h in HEPG2 (Carcinogenome)
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Genes

1092 genes differentially expressed following the CRCGN014_HEPG2_3H:M13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DNM1 dynamin 1 10.0
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 10.0
NANOS3 nanos homolog 3 (Drosophila) 10.0
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 10.0
CAPN1 calpain 1, (mu/I) large subunit 10.0
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 9.779
LSR lipolysis stimulated lipoprotein receptor 9.111
PLS1 plastin 1 8.6892
RPL39L ribosomal protein L39-like 8.5366
CASP2 caspase 2, apoptosis-related cysteine peptidase 8.22532
MUC1 mucin 1, cell surface associated 7.59863
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 7.07148
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 6.617
TIAM1 T-cell lymphoma invasion and metastasis 1 6.56185
ZBTB18 zinc finger and BTB domain containing 18 6.0586
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 5.99455
SCYL3 SCY1-like 3 (S. cerevisiae) 5.8585
KIFBP kinesin family binding protein 5.8222
MELK maternal embryonic leucine zipper kinase 5.3056
KCNK1 potassium channel, two pore domain subfamily K, member 1 5.0755
CRTAP cartilage associated protein 4.8199
LCN2 lipocalin 2 4.6953
OXCT1 3-oxoacid CoA transferase 1 4.6839
RRAGA Ras-related GTP binding A 4.6459
HLA-DMA major histocompatibility complex, class II, DM alpha 4.6391
TPD52L2 tumor protein D52-like 2 4.5791
SYNGAP1 synaptic Ras GTPase activating protein 1 4.55175
MAP7 microtubule-associated protein 7 4.2288
DIPK1A divergent protein kinase domain 1A 4.2229
CBR3 carbonyl reductase 3 4.2018
SKIC8 SKI8 subunit of superkiller complex 4.14185
BCL2L2 BCL2-like 2 4.0958
OCLN occludin 4.0545
PLAGL1 pleiomorphic adenoma gene-like 1 4.01403
NSDHL NAD(P) dependent steroid dehydrogenase-like 3.9792
NBPF10 neuroblastoma breakpoint family, member 10 3.9389
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 3.9174
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 3.8937
DNM1L dynamin 1-like 3.8744
DRC4 dynein regulatory complex subunit 4 3.8635
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 3.8381
SNCA synuclein, alpha (non A4 component of amyloid precursor) 3.8179
RECK reversion-inducing-cysteine-rich protein with kazal motifs 3.7022
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 3.6993
LRRC40 leucine rich repeat containing 40 3.671
SYTL2 synaptotagmin-like 2 3.6583
SPINT1 serine peptidase inhibitor, Kunitz type 1 3.658
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 3.605
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 3.5983
INSIG1 insulin induced gene 1 3.5848
SQOR sulfide quinone oxidoreductase 3.5705
CDK9 cyclin-dependent kinase 9 3.5443
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 3.5163
GYPC glycophorin C (Gerbich blood group) 3.5021
SYK spleen tyrosine kinase 3.469
PLPP6 phospholipid phosphatase 6 3.4667
TBKBP1 TBK1 binding protein 1 3.4523
LDHB lactate dehydrogenase B 3.4475
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase 3.437
CD248 CD248 molecule, endosialin 3.4174
BRWD1 bromodomain and WD repeat domain containing 1 3.4158
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 3.3743
CTSL cathepsin L 3.3622
PLXNB2 plexin B2 3.316
GSTZ1 glutathione S-transferase zeta 1 3.3138
HSPA1A heat shock 70kDa protein 1A 3.3116
MSH5 mutS homolog 5 3.2854
VTCN1 V-set domain containing T cell activation inhibitor 1 3.2825
ELAC2 elaC ribonuclease Z 2 3.2734
VCAN versican 3.2726
MEN1 multiple endocrine neoplasia I 3.2705
PRRC1 proline-rich coiled-coil 1 3.27
PTPRD protein tyrosine phosphatase, receptor type, D 3.2387
GULP1 GULP, engulfment adaptor PTB domain containing 1 3.23827
MIS18BP1 MIS18 binding protein 1 3.2353
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 3.2348
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) 3.2276
XPO7 exportin 7 3.2102
NBPF19 neuroblastoma breakpoint family, member 19 3.2072
MRPS17 mitochondrial ribosomal protein S17 3.2061
MFSD6 major facilitator superfamily domain containing 6 3.1937
HBA1 hemoglobin, alpha 1 3.18345
ROPN1B rhophilin associated tail protein 1B 3.1794
MNMIP1 manchette microtubule inner protein 1 3.1657
WWC3 WWC family member 3 3.1631
INTS3 integrator complex subunit 3 3.1596
RASAL1 RAS protein activator like 1 (GAP1 like) 3.1301
DNMBP dynamin binding protein 3.1236
THY1 Thy-1 cell surface antigen 3.09677
LYN LYN proto-oncogene, Src family tyrosine kinase 3.09067
STX1A syntaxin 1A (brain) 3.085
RORB RAR-related orphan receptor B 3.0795
CLTA clathrin, light chain A 3.0529
FUT2 fucosyltransferase 2 (secretor status included) 3.04785
KIAA0513 KIAA0513 3.0393
RPP38 ribonuclease P/MRP 38kDa subunit 3.0189
UBA1 ubiquitin-like modifier activating enzyme 1 3.0181
MKNK1 MAP kinase interacting serine/threonine kinase 1 3.0131
GET1 guided entry of tail-anchored proteins factor 1 3.0089
NUTF2 nuclear transport factor 2 3.0014
RAB11FIP1 RAB11 family interacting protein 1 (class I) 2.9943
HAT1 histone acetyltransferase 1 2.9855
SGSM2 small G protein signaling modulator 2 2.97683
CLASRP CLK4-associating serine/arginine rich protein 2.9705
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 2.9654
NYNRIN NYN domain and retroviral integrase containing 2.9536
NRTN neurturin 2.9492
NT5E 5'-nucleotidase, ecto (CD73) 2.9435
CLINT1 clathrin interactor 1 2.94105
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 2.9347
PABPC1 poly(A) binding protein, cytoplasmic 1 2.9198
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 2.917
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed 2.9072
ADGRE5 adhesion G protein-coupled receptor E5 2.8959
CD83 CD83 molecule 2.8921
TIMP2 TIMP metallopeptidase inhibitor 2 2.882
CPEB1 cytoplasmic polyadenylation element binding protein 1 2.8772
SNCB synuclein, beta 2.8737
DMTN dematin actin binding protein 2.8729
TRPM4 transient receptor potential cation channel, subfamily M, member 4 2.87
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 2.8674
SFT2D2 SFT2 domain containing 2 2.8561
TRIOBP TRIO and F-actin binding protein 2.85553
IGF2R insulin-like growth factor 2 receptor 2.8473
MPV17L-BMERB1 MPV17L-BMERB1 readthrough 2.8291
MBNL1 muscleblind-like splicing regulator 1 2.82568
CLDN7 claudin 7 2.8229
EHBP1L1 EH domain binding protein 1-like 1 2.81865
TBCA tubulin folding cofactor A 2.8064
NDOR1 NADPH dependent diflavin oxidoreductase 1 2.8063
PCSK7 proprotein convertase subtilisin/kexin type 7 2.7961
RIDA reactive intermediate imine deaminase A homolog 2.7924
MRPL49 mitochondrial ribosomal protein L49 2.7862
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.7817
VSNL1 visinin-like 1 2.78025
SMC4 structural maintenance of chromosomes 4 2.77967
NBPF3 neuroblastoma breakpoint family, member 3 2.7765
TUBB4B tubulin, beta 4B class IVb 2.7734
INPP5F inositol polyphosphate-5-phosphatase F 2.7682
GRAMD2B GRAM domain containing 2B 2.766
CCNL2 cyclin L2 2.7631
ATP2A3 ATPase, Ca++ transporting, ubiquitous 2.75577
ACSM3 acyl-CoA synthetase medium-chain family member 3 2.75095
STK17B serine/threonine kinase 17b 2.74995
EYA2 EYA transcriptional coactivator and phosphatase 2 2.741
HMGN1 high mobility group nucleosome binding domain 1 2.7326
MDM4 MDM4, p53 regulator 2.7218
NCOA3 nuclear receptor coactivator 3 2.72003
HBE1 hemoglobin, epsilon 1 2.7199
RPS27A ribosomal protein S27a 2.7167
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 2.7077
BIN3 bridging integrator 3 2.7058
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 2.69742
PCOLCE procollagen C-endopeptidase enhancer 2.6891
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa 2.68775
MRPL19 mitochondrial ribosomal protein L19 2.6858
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) 2.67665
EXOSC4 exosome component 4 2.67483
IGLL1 immunoglobulin lambda-like polypeptide 1 2.6735
PTH1R parathyroid hormone 1 receptor 2.6697
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 2.66693
ADRA2C adrenoceptor alpha 2C 2.6625
ESRP1 epithelial splicing regulatory protein 1 2.6565
MAP3K7 mitogen-activated protein kinase kinase kinase 7 2.6495
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 2.6392
DDHD2 DDHD domain containing 2 2.6385
ERMP1 endoplasmic reticulum metallopeptidase 1 2.6323
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 2.632
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.6312
GPR183 G protein-coupled receptor 183 2.6302
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 2.6284
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 2.6227
H2BC5 H2B clustered histone 5 2.62005
OAT ornithine aminotransferase 2.6191
FBXO34 F-box protein 34 2.6151
ISLR immunoglobulin superfamily containing leucine-rich repeat 2.6144
SPAG7 sperm associated antigen 7 2.6141
GPR137B G protein-coupled receptor 137B 2.6101
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 2.6075
MED20 mediator complex subunit 20 2.60655
GARRE1 granule associated Rac and RHOG effector 1 2.6058
ZNF862 zinc finger protein 862 2.5971
GRB14 growth factor receptor-bound protein 14 2.5931
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 2.5857
CDPF1 cysteine-rich, DPF motif domain containing 1 2.5748
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 2.5676
ABHD11 abhydrolase domain containing 11 2.5537
PARP1 poly (ADP-ribose) polymerase 1 2.5477
UBE2W ubiquitin-conjugating enzyme E2W (putative) 2.5474
ZDHHC13 zinc finger, DHHC-type containing 13 2.5473
CD81 CD81 molecule 2.5462
PRR3 proline rich 3 2.5459
SGPP1 sphingosine-1-phosphate phosphatase 1 2.5422
TMX2 thioredoxin-related transmembrane protein 2 2.5399
CNOT4 CCR4-NOT transcription complex, subunit 4 2.53962
ADAP1 ArfGAP with dual PH domains 1 2.53565
SYNGR1 synaptogyrin 1 2.53527
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 2.5336
TRAPPC6A trafficking protein particle complex 6A 2.5316
EPS8L2 EPS8-like 2 2.5311
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 2.531
CLK4 CDC-like kinase 4 2.5264
KDM5A lysine (K)-specific demethylase 5A 2.5252
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 2.5222
FOXC1 forkhead box C1 2.5174
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 2.516
NUP214 nucleoporin 214kDa 2.5157
LEFTY1 left-right determination factor 1 2.5133
ARF5 ADP-ribosylation factor 5 2.5131
MAD2L1BP MAD2L1 binding protein 2.5118
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 2.5077
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 2.5018
ZNF638 zinc finger protein 638 2.497
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 2.4952
CCNH cyclin H 2.4927
PRKCQ protein kinase C, theta 2.49015
EMX2 empty spiracles homeobox 2 2.4898
RAP2C RAP2C, member of RAS oncogene family 2.48105
SLC16A6 solute carrier family 16, member 6 2.4786
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.4782
SF3B2 splicing factor 3b, subunit 2, 145kDa 2.4775
ADD3 adducin 3 (gamma) 2.4752
SYN1 synapsin I 2.4732
ALAS2 5'-aminolevulinate synthase 2 2.4718
EMC10 ER membrane protein complex subunit 10 2.4685
CRABP2 cellular retinoic acid binding protein 2 2.4665
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 2.4658
TSPYL1 TSPY-like 1 2.4644
FMO1 flavin containing monooxygenase 1 2.4603
CTBP2 C-terminal binding protein 2 2.4534
TTLL3 tubulin tyrosine ligase-like family member 3 2.45245
UBA6 ubiquitin-like modifier activating enzyme 6 2.4508
IL19 interleukin 19 2.4462
GOLT1A golgi transport 1A 2.4457
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 2.44225
TMEM40 transmembrane protein 40 2.4411
GPR20 G protein-coupled receptor 20 2.4377
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2.43173
EPB41L1 erythrocyte membrane protein band 4.1-like 1 2.4245
AFTPH aftiphilin 2.424
CLDND1 claudin domain containing 1 2.4238
ARMCX1 armadillo repeat containing, X-linked 1 2.4237
POLM polymerase (DNA directed), mu 2.4217
CEP192 centrosomal protein 192kDa 2.4177
STRN3 striatin, calmodulin binding protein 3 2.4171
MAG myelin associated glycoprotein 2.4163
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 2.4113
CUEDC1 CUE domain containing 1 2.4099
TMED3 transmembrane emp24 protein transport domain containing 3 2.4096
RANBP17 RAN binding protein 17 2.4073
ST14 suppression of tumorigenicity 14 (colon carcinoma) 2.4065
CPZ carboxypeptidase Z 2.4039
TJP3 tight junction protein 3 2.40345
TYR tyrosinase 2.4027
PGAP4 post-GPI attachment to proteins GalNAc transferase 4 2.4001
BSPRY B-box and SPRY domain containing 2.398
IFFO1 intermediate filament family orphan 1 2.398
DBN1 drebrin 1 2.3978
AAMP angio-associated, migratory cell protein 2.3948
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.3936
CISH cytokine inducible SH2-containing protein 2.3928
ANO1 anoctamin 1, calcium activated chloride channel 2.3877
LRRC15 leucine rich repeat containing 15 2.3859
AOC1 amine oxidase, copper containing 1 2.3841
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 2.382
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 2.3811
ERLIN2 ER lipid raft associated 2 2.37595
TLN2 talin 2 2.37085
AAR2 AAR2 splicing factor homolog (S. cerevisiae) 2.3662
CGGBP1 CGG triplet repeat binding protein 1 2.3656
CDK13 cyclin-dependent kinase 13 2.36183
EI24 etoposide induced 2.4 2.3613
LPAR2 lysophosphatidic acid receptor 2 2.36065
CALCR calcitonin receptor 2.35975
ZNF592 zinc finger protein 592 2.35495
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 2.3532
MRS2 MRS2 magnesium transporter 2.3525
H2BC4 H2B clustered histone 4 2.35224
DHDDS dehydrodolichyl diphosphate synthase 2.3518
U2SURP U2 snRNP-associated SURP domain containing 2.34757
TMEM151B transmembrane protein 151B 2.34715
ZBTB10 zinc finger and BTB domain containing 10 2.3446
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.3414
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 2.3407
KRT83 keratin 83, type II 2.3397
UBE2G2 ubiquitin-conjugating enzyme E2G 2 2.3372
TLK2 tousled-like kinase 2 2.3305
LIPC lipase, hepatic 2.3277
KRT81 keratin 81, type II 2.3249
PDE8A phosphodiesterase 8A 2.32475
EHF ets homologous factor 2.3241
COL18A1 collagen, type XVIII, alpha 1 2.32345
DEFB1 defensin, beta 1 2.3229
EFHD1 EF-hand domain family, member D1 2.3221
TCL1A T-cell leukemia/lymphoma 1A 2.32055
PAX9 paired box 9 2.3184
KLF10 Kruppel-like factor 10 2.3145
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 2.3114
EVA1B eva-1 homolog B (C. elegans) 2.30815
STX3 syntaxin 3 2.3076
RHCG Rh family, C glycoprotein 2.3058
KRT8 keratin 8, type II 2.3015
NPTN neuroplastin 2.2987
CA1 carbonic anhydrase I 2.2974
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 2.2965
MFAP5 microfibrillar associated protein 5 2.29627
CXCL12 chemokine (C-X-C motif) ligand 12 2.29585
CSN1S1 casein alpha s1 2.2941
SLCO1B3 solute carrier organic anion transporter family, member 1B3 2.2934
SPINT2 serine peptidase inhibitor, Kunitz type, 2 2.2929
EPCAM epithelial cell adhesion molecule 2.2909
GSTP1 glutathione S-transferase pi 1 2.2869
EBNA1BP2 EBNA1 binding protein 2 2.2856
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 2.2832
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 2.2805
MRPS2 mitochondrial ribosomal protein S2 2.2739
HGD homogentisate 1,2-dioxygenase 2.2713
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 2.2712
OLFML2B olfactomedin-like 2B 2.271
PEX6 peroxisomal biogenesis factor 6 2.269
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 2.269
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 2.26705
RAG2 recombination activating gene 2 2.2663
XYLT1 xylosyltransferase I 2.2657
PHEX phosphate regulating endopeptidase homolog, X-linked 2.2629
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 2.2614
KCTD11 potassium channel tetramerization domain containing 11 2.2611
PTGIS prostaglandin I2 (prostacyclin) synthase 2.2571
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 2.2559
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 2.254
NOTCH2 notch 2 2.25032
HACD3 3-hydroxyacyl-CoA dehydratase 3 2.2501
EBLN2 endogenous Bornavirus-like nucleoprotein 2 2.2501
ARHGAP5 Rho GTPase activating protein 5 2.2491
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.2489
KLHL36 kelch-like family member 36 2.2486
CD72 CD72 molecule 2.2484
ZNF692 zinc finger protein 692 2.248
CKAP5 cytoskeleton associated protein 5 2.2468
TRIM38 tripartite motif containing 38 2.246
SIDT1 SID1 transmembrane family, member 1 2.2453
DIABLO diablo, IAP-binding mitochondrial protein 2.2446
CCKBR cholecystokinin B receptor 2.2442
DAAM2 dishevelled associated activator of morphogenesis 2 2.244
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 2.2438
GRPR gastrin-releasing peptide receptor 2.2391
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 2.2385
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 2.238
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 2.2379
BAG4 BCL2-associated athanogene 4 2.2337
TTC9 tetratricopeptide repeat domain 9 2.2327
SH3D19 SH3 domain containing 19 2.23225
APLP2 amyloid beta (A4) precursor-like protein 2 2.23113
SH3GL3 SH3-domain GRB2-like 3 2.2308
TDP1 tyrosyl-DNA phosphodiesterase 1 2.2281
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.224
LYRM1 LYR motif containing 1 2.2238
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 2.2223
ASB1 ankyrin repeat and SOCS box containing 1 2.22195
PSORS1C1 psoriasis susceptibility 1 candidate 1 2.22
ASL argininosuccinate lyase 2.2198
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 2.2196
OCA2 oculocutaneous albinism II 2.218
SH3GLB2 SH3-domain GRB2-like endophilin B2 2.2173
LIMD2 LIM domain containing 2 2.2092
PRSS23 protease, serine, 23 2.2087
SNUPN snurportin 1 2.2074
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 2.2059
WASF1 WAS protein family, member 1 2.2052
GSK3B glycogen synthase kinase 3 beta 2.2033
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 2.2029
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 2.20263
JMJD1C jumonji domain containing 1C 2.2022
LDAF1 lipid droplet assembly factor 1 2.2021
MTA2 metastasis associated 1 family, member 2 2.1997
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 2.19917
STAU2 staufen double-stranded RNA binding protein 2 2.1981
PSG5 pregnancy specific beta-1-glycoprotein 5 2.1975
RPL21 ribosomal protein L21 2.1966
CNTFR ciliary neurotrophic factor receptor 2.1965
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 2.1936
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.1924
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 2.19185
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 2.1892
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 2.1886
CDK16 cyclin-dependent kinase 16 2.1883
PENK proenkephalin 2.1871
ECM1 extracellular matrix protein 1 2.1863
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 2.1849
RPL11 ribosomal protein L11 2.1839
TMEM120B transmembrane protein 120B 2.1832
NUP54 nucleoporin 54kDa 2.1769
RUBCNL rubicon like autophagy enhancer 2.1752
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 2.1702
NPY4R2 neuropeptide Y receptor Y4-2 2.1682
PROM1 prominin 1 2.1676
POLI polymerase (DNA directed) iota 2.1667
H2BC12 H2B clustered histone 12 2.16635
SSRP1 structure specific recognition protein 1 2.16595
ASRGL1 asparaginase like 1 2.1626
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 2.1617
CRABP1 cellular retinoic acid binding protein 1 2.1614
PRAMEF12 PRAME family member 12 2.1603
LPIN2 lipin 2 2.16025
RBM47 RNA binding motif protein 47 2.1602
BICD2 bicaudal D homolog 2 (Drosophila) 2.15977
KCTD7 potassium channel tetramerization domain containing 7 2.1597
AP2A2 adaptor-related protein complex 2, alpha 2 subunit 2.15823
NFYA nuclear transcription factor Y, alpha 2.1581
PNMA8A PNMA family member 8A 2.1566
CDK20 cyclin-dependent kinase 20 2.1527
MAP3K3 mitogen-activated protein kinase kinase kinase 3 2.1525
IL16 interleukin 16 2.14855
CAPN6 calpain 6 2.1484
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 2.14735
PPCDC phosphopantothenoylcysteine decarboxylase 2.1468
LSM1 LSM1, U6 small nuclear RNA associated 2.1464
EHD1 EH-domain containing 1 2.14622
PYCARD PYD and CARD domain containing 2.1461
KLF4 Kruppel-like factor 4 (gut) 2.1449
ORAI3 ORAI calcium release-activated calcium modulator 3 2.1447
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 2.1388
NELFB negative elongation factor complex member B 2.138
GPR18 G protein-coupled receptor 18 2.136
GPR143 G protein-coupled receptor 143 2.1346
GIPC1 GIPC PDZ domain containing family, member 1 2.1318
SNX16 sorting nexin 16 2.1307
ZFYVE21 zinc finger, FYVE domain containing 21 2.1306
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 2.1293
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 2.1275
CLDN4 claudin 4 2.1267
CTSK cathepsin K 2.1256
SNIP1 Smad nuclear interacting protein 1 2.1211
TBC1D13 TBC1 domain family, member 13 2.1209
GRAP2 GRB2-related adaptor protein 2 2.1192
ZWINT ZW10 interacting kinetochore protein 2.119
FBLN2 fibulin 2 2.1172
PTPN6 protein tyrosine phosphatase, non-receptor type 6 2.1166
ZNF835 zinc finger protein 835 2.1146
PILRB paired immunoglobin-like type 2 receptor beta 2.1136
KCTD5 potassium channel tetramerization domain containing 5 2.1134
IGF1 insulin-like growth factor 1 (somatomedin C) 2.11223
CPOX coproporphyrinogen oxidase 2.1098
SFRP1 secreted frizzled-related protein 1 2.10893
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 2.10805
ATP5PF ATP synthase peripheral stalk subunit F6 2.1073
CYB5R2 cytochrome b5 reductase 2 2.1069
PREPL prolyl endopeptidase-like 2.10533
NPIPB5 nuclear pore complex interacting protein family, member B5 2.1026
CEMIP2 cell migration inducing hyaluronidase 2 2.1021
DPP8 dipeptidyl-peptidase 8 2.0998
EZR ezrin 2.09893
DPY19L4 dpy-19-like 4 (C. elegans) 2.0969
CLDN10 claudin 10 2.0966
SIRT6 sirtuin 6 2.0958
RLIM ring finger protein, LIM domain interacting 2.0951
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 2.0947
IL12A interleukin 12A 2.0886
DOK3 docking protein 3 2.0858
AEBP1 AE binding protein 1 2.0855
ANGPTL2 angiopoietin-like 2 2.0838
CA2 carbonic anhydrase II 2.082
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 2.0784
HBB hemoglobin, beta 2.0784
MED23 mediator complex subunit 23 2.0746
PADI2 peptidyl arginine deiminase, type II 2.0731
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) 2.0726
INTS8 integrator complex subunit 8 2.0717
ITPKB inositol-trisphosphate 3-kinase B 2.0716
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 2.06967
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 2.0688
TUBB2A tubulin, beta 2A class IIa 2.06783
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 2.0678
TRO trophinin 2.06725
STAMBP STAM binding protein 2.0661
GJA3 gap junction protein, alpha 3, 46kDa 2.0661
SNAP91 synaptosomal-associated protein, 91kDa 2.0628
CXCR5 chemokine (C-X-C motif) receptor 5 2.0613
DDR2 discoidin domain receptor tyrosine kinase 2 2.0608
MALT1 MALT1 paracaspase 2.06073
MUC5B mucin 5B, oligomeric mucus/gel-forming 2.0593
COL5A2 collagen, type V, alpha 2 2.05795
DOC2A double C2-like domains, alpha 2.0562
PRPF39 pre-mRNA processing factor 39 2.0553
NASP nuclear autoantigenic sperm protein (histone-binding) 2.05445
S100A14 S100 calcium binding protein A14 2.0528
KIF3A kinesin family member 3A 2.0528
GCC1 GRIP and coiled-coil domain containing 1 2.0521
DIRAS2 DIRAS family, GTP-binding RAS-like 2 2.0518
TNXB tenascin XB 2.05132
SCAMP4 secretory carrier membrane protein 4 2.05
RASA2 RAS p21 protein activator 2 2.0482
PHACTR1 phosphatase and actin regulator 1 2.048
JAK1 Janus kinase 1 2.0475
CTRB2 chymotrypsinogen B2 2.0469
FAM3C family with sequence similarity 3, member C 2.0458
FAF2 Fas associated factor family member 2 2.0444
CETN3 centrin, EF-hand protein, 3 2.0434
RABGAP1L RAB GTPase activating protein 1-like 2.04297
SASH1 SAM and SH3 domain containing 1 2.04285
CCNG2 cyclin G2 2.04267
RSRC1 arginine/serine-rich coiled-coil 1 2.0426
OGN osteoglycin 2.0401
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 2.0393
NAT8 N-acetyltransferase 8 (GCN5-related, putative) 2.03697
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 2.03667
CTSV cathepsin V 2.0347
CD24 CD24 molecule 2.03392
RC3H2 ring finger and CCCH-type domains 2 2.03305
MAST2 microtubule associated serine/threonine kinase 2 2.03267
LIMA1 LIM domain and actin binding 1 2.0322
PCDHGA9 protocadherin gamma subfamily A, 9 2.0298
DZIP1 DAZ interacting zinc finger protein 1 2.02975
PRR14L proline rich 14-like 2.0295
PTPN9 protein tyrosine phosphatase, non-receptor type 9 2.0265
COL14A1 collagen, type XIV, alpha 1 2.0254
TWSG1 twisted gastrulation BMP signaling modulator 1 2.022
FIP1L1 factor interacting with PAPOLA and CPSF1 2.0216
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 2.0208
PLPP2 phospholipid phosphatase 2 2.0196
DLAT dihydrolipoamide S-acetyltransferase 2.01923
PSG6 pregnancy specific beta-1-glycoprotein 6 2.0168
CATSPERB catsper channel auxiliary subunit beta 2.016
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 2.0154
BTN2A1 butyrophilin, subfamily 2, member A1 2.0148
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 2.0111
GFPT1 glutamine--fructose-6-phosphate transaminase 1 2.00785
KCTD9 potassium channel tetramerization domain containing 9 2.0068
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 2.0059
ADGRG6 adhesion G protein-coupled receptor G6 2.0056
HBS1L HBS1-like translational GTPase 2.00517
PMM2 phosphomannomutase 2 2.0029
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 2.0002

decreased expression

Symbol Name Standardized Value
DERA deoxyribose-phosphate aldolase (putative) -10.0
LAP3 leucine aminopeptidase 3 -10.0
CD320 CD320 molecule -10.0
ADI1 acireductone dioxygenase 1 -10.0
THAP11 THAP domain containing 11 -10.0
UBE3C ubiquitin protein ligase E3C -9.5908
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -9.5858
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -9.3124
KDM3A lysine (K)-specific demethylase 3A -8.3613
ARID5B AT rich interactive domain 5B (MRF1-like) -7.9438
TLCD3A TLC domain containing 3A -7.8994
YME1L1 YME1-like 1 ATPase -7.73523
BDH1 3-hydroxybutyrate dehydrogenase, type 1 -7.4843
WDR7 WD repeat domain 7 -6.5708
LOC124907782 dual specificity protein phosphatase 22 -6.4493
TLR4 toll-like receptor 4 -6.126
NT5DC2 5'-nucleotidase domain containing 2 -5.5545
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -5.4922
POLR3B polymerase (RNA) III (DNA directed) polypeptide B -5.2829
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -5.028
STAT1 signal transducer and activator of transcription 1, 91kDa -5.0103
TACC2 transforming, acidic coiled-coil containing protein 2 -4.59185
BPHL biphenyl hydrolase-like (serine hydrolase) -4.4593
MAGEA1 melanoma antigen family A1 -4.4491
PIH1D1 PIH1 domain containing 1 -4.4361
LRRC41 leucine rich repeat containing 41 -4.42935
AKAP8 A kinase (PRKA) anchor protein 8 -4.41265
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -4.29465
EIF5 eukaryotic translation initiation factor 5 -4.26822
KIF15 kinesin family member 15 -4.2631
PCCB propionyl CoA carboxylase, beta polypeptide -4.2027
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) -4.1055
CIAPIN1 cytokine induced apoptosis inhibitor 1 -4.09765
THAP3 THAP domain containing, apoptosis associated protein 3 -4.0876
CD3D CD3d molecule, delta (CD3-TCR complex) -4.0586
SRGN serglycin -4.0449
KCMF1 potassium channel modulatory factor 1 -4.0244
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) -3.9212
RPIA ribose 5-phosphate isomerase A -3.8783
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -3.8208
ANXA8L1 annexin A8-like 1 -3.7637
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) -3.7557
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) -3.7551
RIC8B RIC8 guanine nucleotide exchange factor B -3.7317
RNF2 ring finger protein 2 -3.7101
PNPO pyridoxamine 5'-phosphate oxidase -3.7001
HPRT1 hypoxanthine phosphoribosyltransferase 1 -3.6928
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -3.6876
MCTP1 multiple C2 domains, transmembrane 1 -3.6707
ITGB1BP1 integrin beta 1 binding protein 1 -3.65755
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -3.5952
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 -3.574
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -3.5719
TXNL4B thioredoxin-like 4B -3.5523
ZFP69B ZFP69 zinc finger protein B -3.5226
TDG thymine-DNA glycosylase -3.5044
NBAS neuroblastoma amplified sequence -3.4882
ELL2 elongation factor, RNA polymerase II, 2 -3.4728
MUTYH mutY homolog -3.4688
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -3.4644
CRADD CASP2 and RIPK1 domain containing adaptor with death domain -3.4572
PAGE1 P antigen family, member 1 (prostate associated) -3.4477
CAB39 calcium binding protein 39 -3.4222
IPO13 importin 13 -3.4194
GLIPR1 GLI pathogenesis-related 1 -3.41577
WASHC3 WASH complex subunit 3 -3.4076
ERCC6L excision repair cross-complementation group 6-like -3.4068
BOLA1 bolA family member 1 -3.3935
WARS1 tryptophanyl-tRNA synthetase 1 -3.3913
MYF6 myogenic factor 6 (herculin) -3.3704
BLMH bleomycin hydrolase -3.3569
BST2 bone marrow stromal cell antigen 2 -3.3478
ZNF706 zinc finger protein 706 -3.3476
CA3 carbonic anhydrase III -3.3363
TCTN1 tectonic family member 1 -3.3307
COMMD3 COMM domain containing 3 -3.3127
C1QA complement component 1, q subcomponent, A chain -3.3011
CDK17 cyclin-dependent kinase 17 -3.29255
IL33 interleukin 33 -3.2853
MRPL34 mitochondrial ribosomal protein L34 -3.277
FKBP14 FK506 binding protein 14, 22 kDa -3.2744
RPN1 ribophorin I -3.267
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 -3.2526
ISG15 ISG15 ubiquitin-like modifier -3.236
INSIG2 insulin induced gene 2 -3.2311
DEPP1 DEPP autophagy regulator 1 -3.22805
TBX3 T-box 3 -3.2213
CYBRD1 cytochrome b reductase 1 -3.1967
SIX3 SIX homeobox 3 -3.1865
SNX11 sorting nexin 11 -3.1865
SOCS3 suppressor of cytokine signaling 3 -3.1653
GPR88 G protein-coupled receptor 88 -3.1594
TENM3 teneurin transmembrane protein 3 -3.1489
MTPAP mitochondrial poly(A) polymerase -3.1469
GSTM4 glutathione S-transferase mu 4 -3.14243
ANOS1 anosmin 1 -3.1373
THSD1 thrombospondin, type I, domain containing 1 -3.1372
THNSL1 threonine synthase-like 1 (S. cerevisiae) -3.1304
GBP2 guanylate binding protein 2, interferon-inducible -3.1279
ZNF586 zinc finger protein 586 -3.1171
NUCB1 nucleobindin 1 -3.0817
C1QB complement component 1, q subcomponent, B chain -3.0695
RPP40 ribonuclease P/MRP 40kDa subunit -3.0681
ZNF32 zinc finger protein 32 -3.05
MRPL33 mitochondrial ribosomal protein L33 -3.0465
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.0395
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing -3.0356
HTRA1 HtrA serine peptidase 1 -3.0242
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -3.0207
ADAR adenosine deaminase, RNA-specific -3.0196
MTARC2 mitochondrial amidoxime reducing component 2 -2.99505
DGKB diacylglycerol kinase, beta 90kDa -2.9859
WASF3 WAS protein family, member 3 -2.9774
KCNIP1 Kv channel interacting protein 1 -2.9772
ABI1 abl-interactor 1 -2.97485
DRD4 dopamine receptor D4 -2.9679
ACKR5 atypical chemokine receptor 5 -2.9628
KIF14 kinesin family member 14 -2.9569
HSPB8 heat shock 22kDa protein 8 -2.9544
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa -2.9507
MCM10 minichromosome maintenance complex component 10 -2.9472
EXOSC5 exosome component 5 -2.9367
PARP12 poly (ADP-ribose) polymerase family, member 12 -2.9323
FDX1 ferredoxin 1 -2.9321
HIRIP3 HIRA interacting protein 3 -2.9162
SV2C synaptic vesicle glycoprotein 2C -2.9038
MRPL3 mitochondrial ribosomal protein L3 -2.9005
TIMP4 TIMP metallopeptidase inhibitor 4 -2.8969
LPL lipoprotein lipase -2.896
ZNF324B zinc finger protein 324B -2.892
LHB luteinizing hormone beta polypeptide -2.8893
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 -2.8893
RXRA retinoid X receptor, alpha -2.8837
RPF1 ribosome production factor 1 homolog (S. cerevisiae) -2.8712
PARK7 parkinson protein 7 -2.8697
ARHGAP15 Rho GTPase activating protein 15 -2.8621
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -2.8616
IFI35 interferon-induced protein 35 -2.857
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -2.85655
TMEM212 transmembrane protein 212 -2.8547
DOLPP1 dolichyldiphosphatase 1 -2.8539
DACH1 dachshund family transcription factor 1 -2.85345
GSTM2 glutathione S-transferase mu 2 (muscle) -2.85035
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) -2.8477
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa -2.8473
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 -2.8398
CNBP CCHC-type zinc finger, nucleic acid binding protein -2.8167
IFI44L interferon-induced protein 44-like -2.814
BORCS8 BLOC-1 related complex subunit 8 -2.8079
CLTCL1 clathrin, heavy chain-like 1 -2.8066
CUTA cutA divalent cation tolerance homolog (E. coli) -2.8005
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -2.7989
KRT10 keratin 10, type I -2.7946
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) -2.7944
INTS12 integrator complex subunit 12 -2.7931
FARSA phenylalanyl-tRNA synthetase, alpha subunit -2.79115
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -2.7907
SLC38A2 solute carrier family 38, member 2 -2.79055
AVPI1 arginine vasopressin-induced 1 -2.786
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -2.7801
MTTP microsomal triglyceride transfer protein -2.7771
SYNPO synaptopodin -2.7771
RBKS ribokinase -2.77485
RCL1 RNA terminal phosphate cyclase-like 1 -2.7696
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C -2.7694
EXOSC8 exosome component 8 -2.7634
NXF2B nuclear RNA export factor 2B -2.75625
PXDC1 PX domain containing 1 -2.7547
TCEAL9 transcription elongation factor A like 9 -2.7543
AGER advanced glycosylation end product-specific receptor -2.75365
DUSP3 dual specificity phosphatase 3 -2.74897
ATG4A autophagy related 4A, cysteine peptidase -2.7483
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 -2.7477
UNC13A unc-13 homolog A (C. elegans) -2.7466
TXNDC15 thioredoxin domain containing 15 -2.7439
PTPRM protein tyrosine phosphatase, receptor type, M -2.7435
KATNB1 katanin p80 (WD repeat containing) subunit B 1 -2.7353
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -2.7294
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit -2.7284
FOXD1 forkhead box D1 -2.7273
CDH5 cadherin 5, type 2 (vascular endothelium) -2.7218
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -2.7199
KIF4A kinesin family member 4A -2.7155
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -2.69855
BEX3 brain expressed X-linked 3 -2.6973
ARL5A ADP-ribosylation factor-like 5A -2.6914
IRF9 interferon regulatory factor 9 -2.6855
ANGPT1 angiopoietin 1 -2.68105
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 -2.67693
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.67635
FAM50B family with sequence similarity 50, member B -2.673
KIF18B kinesin family member 18B -2.6686
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -2.66793
CCL16 chemokine (C-C motif) ligand 16 -2.6622
SEC61B Sec61 beta subunit -2.6622
RNF167 ring finger protein 167 -2.6609
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa -2.658
KPTN kaptin (actin binding protein) -2.6555
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 -2.6554
BMAL1 basic helix-loop-helix ARNT like 1 -2.6501
APOC3 apolipoprotein C-III -2.6425
TBC1D31 TBC1 domain family, member 31 -2.6333
FABP6 fatty acid binding protein 6, ileal -2.6306
BTNL3 butyrophilin-like 3 -2.6294
SLAMF8 SLAM family member 8 -2.62885
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -2.6206
HOXC13 homeobox C13 -2.6185
CENPA centromere protein A -2.61715
LRRC47 leucine rich repeat containing 47 -2.6159
KLF5 Kruppel-like factor 5 (intestinal) -2.61365
GET3 guided entry of tail-anchored proteins factor 3, ATPase -2.6115
ERC1 ELKS/RAB6-interacting/CAST family member 1 -2.6113
LAMB3 laminin, beta 3 -2.6109
ASDURF ASNSD1 upstream open reading frame -2.6088
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -2.6086
TFDP3 transcription factor Dp family, member 3 -2.6032
JADE1 jade family PHD finger 1 -2.5956
RHOB ras homolog family member B -2.5932
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) -2.5892
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -2.5832
COL17A1 collagen, type XVII, alpha 1 -2.5792
CSAG2 CSAG family, member 2 -2.5752
CRY1 cryptochrome circadian clock 1 -2.5749
MYDGF myeloid-derived growth factor -2.57315
TEX11 testis expressed 11 -2.5727
LMO4 LIM domain only 4 -2.57085
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) -2.5673
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -2.5671
CARD10 caspase recruitment domain family, member 10 -2.5651
RABEPK Rab9 effector protein with kelch motifs -2.5636
CNKSR1 connector enhancer of kinase suppressor of Ras 1 -2.5628
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) -2.5607
LY6G5C lymphocyte antigen 6 complex, locus G5C -2.5574
SLC25A46 solute carrier family 25, member 46 -2.5544
PUS7 pseudouridylate synthase 7 (putative) -2.553
RPL3L ribosomal protein L3-like -2.5525
TMEM208 transmembrane protein 208 -2.5467
WNT8B wingless-type MMTV integration site family, member 8B -2.5438
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.5416
MPPED2 metallophosphoesterase domain containing 2 -2.5402
VSIG4 V-set and immunoglobulin domain containing 4 -2.5397
RHOT1 ras homolog family member T1 -2.5359
WASHC4 WASH complex subunit 4 -2.53553
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -2.5346
PDPN podoplanin -2.5345
FBXO46 F-box protein 46 -2.5341
ZW10 zw10 kinetochore protein -2.5338
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -2.5291
SSR1 signal sequence receptor, alpha -2.52588
ADNP2 ADNP homeobox 2 -2.5228
RRAGB Ras-related GTP binding B -2.5192
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G -2.5171
AOC3 amine oxidase, copper containing 3 -2.5137
CDH19 cadherin 19, type 2 -2.51065
NR1I3 nuclear receptor subfamily 1, group I, member 3 -2.5101
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 -2.509
DMBT1 deleted in malignant brain tumors 1 -2.5067
PALMD palmdelphin -2.5033
GTPBP6 GTP binding protein 6 (putative) -2.5028
TRAFD1 TRAF-type zinc finger domain containing 1 -2.49615
MAT2B methionine adenosyltransferase II, beta -2.4939
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 -2.492
PTPRB protein tyrosine phosphatase, receptor type, B -2.4894
IFT22 intraflagellar transport 22 -2.4891
STON1 stonin 1 -2.4819
IRF3 interferon regulatory factor 3 -2.4816
ABHD14A abhydrolase domain containing 14A -2.4798
ZNF473 zinc finger protein 473 -2.4731
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.4702
LOC100533997 MAGEA10-MAGEA5 readthrough -2.4679
PDIA6 protein disulfide isomerase family A, member 6 -2.46747
SKA1 spindle and kinetochore associated complex subunit 1 -2.4666
SEH1L SEH1-like (S. cerevisiae) -2.4665
NBR1 neighbor of BRCA1 gene 1 -2.4651
TRAIP TRAF interacting protein -2.4633
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 -2.4632
THAP12 THAP domain containing 12 -2.4626
CDO1 cysteine dioxygenase type 1 -2.4621
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -2.45743
IFI16 interferon, gamma-inducible protein 16 -2.4564
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -2.44915
CORO1A coronin, actin binding protein, 1A -2.4445
CDCA3 cell division cycle associated 3 -2.4408
HBEGF heparin-binding EGF-like growth factor -2.43815
PWP1 PWP1 homolog (S. cerevisiae) -2.4293
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A -2.4279
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -2.42615
PCDH8 protocadherin 8 -2.423
RWDD2A RWD domain containing 2A -2.4199
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -2.4182
FCHO1 FCH domain only 1 -2.4179
GBP1 guanylate binding protein 1, interferon-inducible -2.417
JTB jumping translocation breakpoint -2.41153
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa -2.4045
AAMDC adipogenesis associated, Mth938 domain containing -2.40435
SPATS2 spermatogenesis associated, serine-rich 2 -2.3959
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 -2.3939
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -2.3929
APH1A APH1A gamma secretase subunit -2.3916
MICALL2 MICAL-like 2 -2.3914
NCAPH non-SMC condensin I complex, subunit H -2.3903
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 -2.3866
KIF17 kinesin family member 17 -2.3862
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 -2.3852
NOP14 NOP14 nucleolar protein -2.3807
AUNIP aurora kinase A and ninein interacting protein -2.3796
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 -2.3789
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 -2.3766
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor -2.3739
NR1H3 nuclear receptor subfamily 1, group H, member 3 -2.3713
SLCO2B1 solute carrier organic anion transporter family, member 2B1 -2.37113
FGF12 fibroblast growth factor 12 -2.369
IL32 interleukin 32 -2.3678
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 -2.3658
CHEK1 checkpoint kinase 1 -2.3655
OSBPL8 oxysterol binding protein-like 8 -2.3643
RNF113A ring finger protein 113A -2.3633
PTPRR protein tyrosine phosphatase, receptor type, R -2.36135
PECAM1 platelet/endothelial cell adhesion molecule 1 -2.3607
VKORC1 vitamin K epoxide reductase complex, subunit 1 -2.3597
INTS7 integrator complex subunit 7 -2.3591
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 -2.3582
BHLHE41 basic helix-loop-helix family, member e41 -2.3556
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta -2.3501
YJU2B YJU2 splicing factor homolog B -2.3491
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 -2.34535
WNT1 wingless-type MMTV integration site family, member 1 -2.3452
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 -2.3445
CHRM3 cholinergic receptor, muscarinic 3 -2.3443
EPAS1 endothelial PAS domain protein 1 -2.34355
FKBP11 FK506 binding protein 11, 19 kDa -2.343
MRPL9 mitochondrial ribosomal protein L9 -2.34255
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) -2.342
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 -2.3404
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -2.3393
NFYB nuclear transcription factor Y, beta -2.3374
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 -2.3364
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 -2.3363
JAG1 jagged 1 -2.33483
MAGEA4 melanoma antigen family A4 -2.3309
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 -2.3298
TXNL4A thioredoxin-like 4A -2.32935
CDK6 cyclin-dependent kinase 6 -2.3284
IFT46 intraflagellar transport 46 -2.3269
TYROBP TYRO protein tyrosine kinase binding protein -2.3238
IFRD2 interferon-related developmental regulator 2 -2.3234
CTNNA2 catenin (cadherin-associated protein), alpha 2 -2.3227
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -2.3222
CRTC3 CREB regulated transcription coactivator 3 -2.3171
KRT17 keratin 17, type I -2.3167
TEX2 testis expressed 2 -2.3149
GSTT1 glutathione S-transferase theta 1 -2.3101
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) -2.30935
CENPI centromere protein I -2.3083
AHR aryl hydrocarbon receptor -2.3076
MYL11 myosin light chain 11 -2.307
DCLRE1B DNA cross-link repair 1B -2.3056
DUSP28 dual specificity phosphatase 28 -2.3027
CREBL2 cAMP responsive element binding protein-like 2 -2.30087
HOPX HOP homeobox -2.3003
MRC1 mannose receptor, C type 1 -2.2991
OTC ornithine carbamoyltransferase -2.298
TSPAN8 tetraspanin 8 -2.2975
TMEM94 transmembrane protein 94 -2.2972
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -2.2933
P3H2 prolyl 3-hydroxylase 2 -2.2933
SUSD5 sushi domain containing 5 -2.2929
SLC14A2 solute carrier family 14 (urea transporter), member 2 -2.291
CCT7 chaperonin containing TCP1, subunit 7 (eta) -2.2895
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -2.2894
NEFH neurofilament, heavy polypeptide -2.28855
WBP11 WW domain binding protein 11 -2.28655
TMEM9B TMEM9 domain family, member B -2.2865
VWF von Willebrand factor -2.2853
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 -2.2842
SART3 squamous cell carcinoma antigen recognized by T cells 3 -2.28293
CLEC1A C-type lectin domain family 1, member A -2.2781
ZNF428 zinc finger protein 428 -2.2711
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 -2.2658
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.2653
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide -2.2622
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -2.2619
TTK TTK protein kinase -2.2579
HPCAL1 hippocalcin-like 1 -2.25735
RNF220 ring finger protein 220 -2.2571
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.2563
LOC128966622 putative protein N-methyltransferase FAM86B2 -2.2557
ERG v-ets avian erythroblastosis virus E26 oncogene homolog -2.25187
TMEM50A transmembrane protein 50A -2.2518
FBXL5 F-box and leucine-rich repeat protein 5 -2.24805
SOWAHC sosondowah ankyrin repeat domain family member C -2.2454
UTP25 UTP25 small subunit processome component -2.24178
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -2.2389
MMRN2 multimerin 2 -2.2376
ZNF426 zinc finger protein 426 -2.2374
TNNT3 troponin T type 3 (skeletal, fast) -2.2363
SIX6 SIX homeobox 6 -2.2352
LYPD1 LY6/PLAUR domain containing 1 -2.2325
CCSER2 coiled-coil serine-rich protein 2 -2.2318
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -2.2312
EFNA1 ephrin-A1 -2.2298
TMEM45A transmembrane protein 45A -2.2287
IFT70A intraflagellar transport 70A -2.2257
APOC1 apolipoprotein C-I -2.2244
KLHL4 kelch-like family member 4 -2.2236
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 -2.2229
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) -2.222
HDHD5 haloacid dehalogenase like hydrolase domain containing 5 -2.2161
PRKCD protein kinase C, delta -2.2157
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit -2.2136
GMFG glia maturation factor, gamma -2.2125
MON1B MON1 secretory trafficking family member B -2.2123
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -2.2118
MANEA mannosidase, endo-alpha -2.211
CTAG2 cancer/testis antigen 2 -2.21096
DHPS deoxyhypusine synthase -2.20807
CCRL2 chemokine (C-C motif) receptor-like 2 -2.2006
YARS1 tyrosyl-tRNA synthetase 1 -2.2003
WDR74 WD repeat domain 74 -2.19995
FSHB follicle stimulating hormone, beta polypeptide -2.1973
ADORA2B adenosine A2b receptor -2.196
LSG1 large 60S subunit nuclear export GTPase 1 -2.1956
KDM1A lysine (K)-specific demethylase 1A -2.1909
IL2RG interleukin 2 receptor, gamma -2.1874
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -2.1859
IL36G interleukin 36, gamma -2.1827
LYRM4 LYR motif containing 4 -2.1819
CPB2 carboxypeptidase B2 (plasma) -2.1817
GOSR1 golgi SNAP receptor complex member 1 -2.18053
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 -2.17745
TMPRSS3 transmembrane protease, serine 3 -2.1758
FGGY FGGY carbohydrate kinase domain containing -2.1757
ZNF813 zinc finger protein 813 -2.1723
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) -2.1689
PIPOX pipecolic acid oxidase -2.1665
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -2.16605
ODAM odontogenic, ameloblast asssociated -2.1656
PRMT8 protein arginine methyltransferase 8 -2.1636
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 -2.1635
VEZT vezatin, adherens junctions transmembrane protein -2.1634
TACR1 tachykinin receptor 1 -2.16105
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 -2.1605
SERP1 stress-associated endoplasmic reticulum protein 1 -2.16037
GAGE8 G antigen 8 -2.15545
ASTN2 astrotactin 2 -2.1526
APOB apolipoprotein B -2.1524
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -2.1514
KRT38 keratin 38, type I -2.1513
PRDM4 PR domain containing 4 -2.15065
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -2.14995
PPP2R2D protein phosphatase 2, regulatory subunit B, delta -2.1497
SAMHD1 SAM domain and HD domain 1 -2.1497
DGKI diacylglycerol kinase, iota -2.1479
FAM32A family with sequence similarity 32, member A -2.1464
VEGFA vascular endothelial growth factor A -2.1463
RASAL2 RAS protein activator like 2 -2.1457
RHOBTB2 Rho-related BTB domain containing 2 -2.1422
PUM2 pumilio RNA-binding family member 2 -2.14025
EMC6 ER membrane protein complex subunit 6 -2.1391
DVL1 dishevelled segment polarity protein 1 -2.1384
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1) -2.1376
ATRAID all-trans retinoic acid-induced differentiation factor -2.1351
SSX3 synovial sarcoma, X breakpoint 3 -2.1345
PITX2 paired-like homeodomain 2 -2.1326
CD70 CD70 molecule -2.1303
DNASE2B deoxyribonuclease II beta -2.1296
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.1285
EXO1 exonuclease 1 -2.1277
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 -2.126
GPN1 GPN-loop GTPase 1 -2.1253
FTO fat mass and obesity associated -2.1249
CUEDC2 CUE domain containing 2 -2.1231
PALB2 partner and localizer of BRCA2 -2.1225
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) -2.11155
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -2.11
DOK2 docking protein 2, 56kDa -2.1095
GAP43 growth associated protein 43 -2.1082
TEFM transcription elongation factor, mitochondrial -2.1078
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -2.10455
LGALSL lectin, galactoside-binding-like -2.1034
USP18 ubiquitin specific peptidase 18 -2.0992
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme -2.0988
SMAD4 SMAD family member 4 -2.09605
ATG7 autophagy related 7 -2.0955
GCFC2 GC-rich sequence DNA-binding factor 2 -2.0927
LRRTM4 leucine rich repeat transmembrane neuronal 4 -2.0926
ATAD5 ATPase family, AAA domain containing 5 -2.0926
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.0913
HCLS1 hematopoietic cell-specific Lyn substrate 1 -2.0888
SRPRB signal recognition particle receptor, B subunit -2.0887
COMMD3-BMI1 COMMD3-BMI1 readthrough -2.0881
TP63 tumor protein p63 -2.08622
BMP8B bone morphogenetic protein 8b -2.0847
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha -2.0844
MKS1 Meckel syndrome, type 1 -2.0843
LIFR leukemia inhibitory factor receptor alpha -2.0826
MX1 MX dynamin-like GTPase 1 -2.0799
BNC1 basonuclin 1 -2.079
THAP10 THAP domain containing 10 -2.0786
THUMPD2 THUMP domain containing 2 -2.0773
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) -2.0762
CXCL13 chemokine (C-X-C motif) ligand 13 -2.076
TMEM184C transmembrane protein 184C -2.0758
DOCK4 dedicator of cytokinesis 4 -2.0751
HJURP Holliday junction recognition protein -2.0746
CXCL9 chemokine (C-X-C motif) ligand 9 -2.0736
CNGA1 cyclic nucleotide gated channel alpha 1 -2.073
E2F6 E2F transcription factor 6 -2.0723
CYBB cytochrome b-245, beta polypeptide -2.0717
HIGD1B HIG1 hypoxia inducible domain family, member 1B -2.0715
HLA-E major histocompatibility complex, class I, E -2.06887
OXLD1 oxidoreductase-like domain containing 1 -2.06735
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) -2.065
PLEK2 pleckstrin 2 -2.0637
CACNB4 calcium channel, voltage-dependent, beta 4 subunit -2.0622
CHAD chondroadherin -2.0597
SDF2L1 stromal cell-derived factor 2-like 1 -2.0584
MCUB mitochondrial calcium uniporter dominant negative subunit beta -2.058
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 -2.0578
ZCCHC2 zinc finger, CCHC domain containing 2 -2.0556
PAAF1 proteasomal ATPase-associated factor 1 -2.0554
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 -2.0554
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit -2.0543
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -2.0528
UBIAD1 UbiA prenyltransferase domain containing 1 -2.0526
PDLIM3 PDZ and LIM domain 3 -2.05225
ETV2 ets variant 2 -2.0469
C4BPB complement component 4 binding protein, beta -2.0451
CTNND2 catenin (cadherin-associated protein), delta 2 -2.04235
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 -2.0376
CDKN2A cyclin-dependent kinase inhibitor 2A -2.03663
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -2.0358
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -2.0348
PLAAT1 phospholipase A and acyltransferase 1 -2.0304
CRB1 crumbs family member 1, photoreceptor morphogenesis associated -2.0274
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -2.027
MORF4L2 mortality factor 4 like 2 -2.0266
ADAM23 ADAM metallopeptidase domain 23 -2.02595
SCCPDH saccharopine dehydrogenase (putative) -2.0253
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) -2.0245
BMP6 bone morphogenetic protein 6 -2.0233
TM4SF1 transmembrane 4 L six family member 1 -2.01995
GLRX2 glutaredoxin 2 -2.0189
ATF3 activating transcription factor 3 -2.0174
MAGEC1 melanoma antigen family C1 -2.0158
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -2.0136
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -2.013
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like -2.0121
FNDC4 fibronectin type III domain containing 4 -2.0077
RHEB Ras homolog enriched in brain -2.00697
ANG angiogenin, ribonuclease, RNase A family, 5 -2.0069
MYOT myotilin -2.0066
IRF7 interferon regulatory factor 7 -2.0054
AMZ2 archaelysin family metallopeptidase 2 -2.0054
CALCRL calcitonin receptor-like -2.0035
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon -2.0021
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit -2.0008
VAMP8 vesicle-associated membrane protein 8 -2.0007
BLM Bloom syndrome, RecQ helicase-like -2.0003