| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | coumophos 19.85 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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84 genes differentially expressed following the CRCGN014_HEPG2_3H:M16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDIT4 | DNA-damage-inducible transcript 4 | 9.34816 |
| CHN1 | chimerin 1 | 4.54377 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.5128 |
| CBR3 | carbonyl reductase 3 | 4.39577 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.02451 |
| UBQLN2 | ubiquilin 2 | 3.8772 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 3.57146 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 3.49702 |
| LCN2 | lipocalin 2 | 3.4 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 3.32471 |
| IL1B | interleukin 1, beta | 3.30081 |
| STAP2 | signal transducing adaptor family member 2 | 3.29665 |
| CEP57 | centrosomal protein 57kDa | 3.25425 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.20351 |
| KIFBP | kinesin family binding protein | 3.12074 |
| CYCS | cytochrome c, somatic | 2.99324 |
| HEBP1 | heme binding protein 1 | 2.93482 |
| ILK | integrin-linked kinase | 2.84742 |
| CCP110 | centriolar coiled coil protein 110kDa | 2.79187 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 2.7816 |
| MAMLD1 | mastermind-like domain containing 1 | 2.76428 |
| TNIP1 | TNFAIP3 interacting protein 1 | 2.65402 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.63615 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.59543 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.579 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 2.55408 |
| PPIE | peptidylprolyl isomerase E (cyclophilin E) | 2.51708 |
| GATA2 | GATA binding protein 2 | 2.42505 |
| CORO1A | coronin, actin binding protein, 1A | 2.38223 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.35666 |
| ALAS1 | 5'-aminolevulinate synthase 1 | 2.35483 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 2.30649 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 2.24496 |
| SFTPB | surfactant protein B | 2.2168 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.18464 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.17847 |
| SAA2 | serum amyloid A2 | 2.1612 |
| LCMT1 | leucine carboxyl methyltransferase 1 | 2.13854 |
| GOLT1B | golgi transport 1B | 2.09361 |
| EAPP | E2F-associated phosphoprotein | 2.08909 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 2.08568 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 | 2.06474 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.04902 |
| MRPL17 | mitochondrial ribosomal protein L17 | 2.02693 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.00662 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -6.23423 |
| FASTKD5 | FAST kinase domains 5 | -4.85421 |
| TBC1D31 | TBC1 domain family, member 31 | -4.36796 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -4.05359 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -4.00069 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.84186 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -3.67869 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -3.62135 |
| FAIM | Fas apoptotic inhibitory molecule | -3.59549 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.49219 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.44903 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.32142 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.23981 |
| RPN1 | ribophorin I | -3.21154 |
| UBE3C | ubiquitin protein ligase E3C | -3.16748 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.15796 |
| CDC20 | cell division cycle 20 | -3.14227 |
| CDC25B | cell division cycle 25B | -3.13661 |
| CDK1 | cyclin-dependent kinase 1 | -3.03045 |
| ANKRD10 | ankyrin repeat domain 10 | -3.00021 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.97002 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.75834 |
| GNAS | GNAS complex locus | -2.7096 |
| ENOPH1 | enolase-phosphatase 1 | -2.63775 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -2.61812 |
| LRP10 | low density lipoprotein receptor-related protein 10 | -2.59495 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -2.57307 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.531 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.49935 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.45747 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.40332 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.27585 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -2.24715 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | -2.23786 |
| MELK | maternal embryonic leucine zipper kinase | -2.202 |
| PROS1 | protein S (alpha) | -2.08522 |
| HMOX1 | heme oxygenase 1 | -2.04882 |
| RRAGA | Ras-related GTP binding A | -2.0306 |
| COG2 | component of oligomeric golgi complex 2 | -2.01356 |
