CRCGN014_HEPG2_3H:M18 Gene Set
Genes
39 genes differentially expressed following the CRCGN014_HEPG2_3H:M18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
6.40036
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
3.57123
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
3.54297
|
|
JADE2
|
jade family PHD finger 2
|
3.49602
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.46293
|
|
UBQLN2
|
ubiquilin 2
|
3.43122
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
3.37577
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.21708
|
|
SQOR
|
sulfide quinone oxidoreductase
|
3.21306
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.01714
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.00048
|
|
EVL
|
Enah/Vasp-like
|
2.90571
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.79852
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.75073
|
|
STK10
|
serine/threonine kinase 10
|
2.73009
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.43266
|
|
TSPAN6
|
tetraspanin 6
|
2.35436
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.3488
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.29833
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.28906
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.28639
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.08384
|
|
HSPA14
|
heat shock 70kDa protein 14
|
2.06655
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-7.4099
|
|
LDHD
|
lactate dehydrogenase D
|
-6.3214
|
|
CDC20
|
cell division cycle 20
|
-4.01226
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.71545
|
|
DNM1L
|
dynamin 1-like
|
-3.69693
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.63344
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.60295
|
|
VAT1
|
vesicle amine transport 1
|
-3.57805
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.53691
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.2059
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.73585
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.72701
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.61681
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.19984
|
|
ZNF768
|
zinc finger protein 768
|
-2.09204
|
|
GTF2E2
|
general transcription factor IIE, polypeptide 2, beta 34kDa
|
-2.06953
|
