| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | benzyl-alcohol 39.6 um perturbation at 3 h in HEPG2 (Carcinogenome) |
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63 genes differentially expressed following the CRCGN014_HEPG2_3H:M19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 8.52819 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.75441 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 5.47885 |
| BZW2 | basic leucine zipper and W2 domains 2 | 4.5435 |
| CBR3 | carbonyl reductase 3 | 4.51918 |
| CSK | c-src tyrosine kinase | 4.47094 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.40761 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 4.3934 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.35339 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.15811 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 4.00842 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.97827 |
| CYCS | cytochrome c, somatic | 3.93442 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.86967 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.85087 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.43369 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | 3.18781 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 3.1615 |
| CHMP6 | charged multivesicular body protein 6 | 3.03 |
| HYOU1 | hypoxia up-regulated 1 | 2.88731 |
| CCNF | cyclin F | 2.85971 |
| CHEK2 | checkpoint kinase 2 | 2.71765 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.5709 |
| AXIN1 | axin 1 | 2.47458 |
| SATB1 | SATB homeobox 1 | 2.39955 |
| TEX10 | testis expressed 10 | 2.34086 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 2.28478 |
| CORO1A | coronin, actin binding protein, 1A | 2.27436 |
| TBP | TATA box binding protein | 2.25199 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.21582 |
| NOTCH1 | notch 1 | 2.12067 |
| DIPK1A | divergent protein kinase domain 1A | 2.10859 |
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 | 2.10047 |
| USP6NL | USP6 N-terminal like | 2.09955 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF586 | zinc finger protein 586 | -7.03063 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -4.52722 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.1686 |
| LDHD | lactate dehydrogenase D | -4.1485 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.12767 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.88956 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.7463 |
| TLR4 | toll-like receptor 4 | -3.74148 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.5756 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.46231 |
| PLK1 | polo-like kinase 1 | -3.45033 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.38445 |
| GNAS | GNAS complex locus | -3.25402 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -3.19066 |
| TES | testin LIM domain protein | -2.81426 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.74119 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.59839 |
| AURKB | aurora kinase B | -2.52337 |
| CCNH | cyclin H | -2.50409 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -2.49367 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.46605 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.37396 |
| TRIM66 | tripartite motif containing 66 | -2.27914 |
| ANKRD10 | ankyrin repeat domain 10 | -2.22804 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -2.21276 |
| SMC4 | structural maintenance of chromosomes 4 | -2.08896 |
| LGMN | legumain | -2.0144 |
| RNF40 | ring finger protein 40, E3 ubiquitin protein ligase | -2.01019 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -2.00123 |