CRCGN014_HEPG2_3H:N06 Gene Set
Genes
49 genes differentially expressed following the CRCGN014_HEPG2_3H:N06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
10.0
|
|
CHN1
|
chimerin 1
|
5.12019
|
|
E2F2
|
E2F transcription factor 2
|
4.87971
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
4.45386
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
4.26696
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.94323
|
|
UBQLN2
|
ubiquilin 2
|
3.92896
|
|
MAP7
|
microtubule-associated protein 7
|
3.81546
|
|
EAPP
|
E2F-associated phosphoprotein
|
3.70238
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.63612
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.62785
|
|
H2BC12
|
H2B clustered histone 12
|
3.13537
|
|
SFTPB
|
surfactant protein B
|
3.08054
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.04542
|
|
PFKL
|
phosphofructokinase, liver
|
3.03086
|
|
KIF14
|
kinesin family member 14
|
2.97083
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.95482
|
|
HEBP1
|
heme binding protein 1
|
2.8692
|
|
SHC1
|
SHC (Src homology 2 domain containing) transforming protein 1
|
2.84056
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.59353
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.55981
|
|
ADGRG1
|
adhesion G protein-coupled receptor G1
|
2.35065
|
|
FLT4
|
fms-related tyrosine kinase 4
|
2.20778
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.10824
|
|
SNCB
|
synuclein, beta
|
2.10408
|
|
POLG2
|
polymerase (DNA directed), gamma 2, accessory subunit
|
2.07022
|
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
2.02989
|
|
DNAH9
|
dynein, axonemal, heavy chain 9
|
2.02781
|
|
GOLT1B
|
golgi transport 1B
|
2.00224
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.43868
|
|
CCNB2
|
cyclin B2
|
-4.40324
|
|
LDHD
|
lactate dehydrogenase D
|
-4.24404
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.10571
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-3.80462
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-3.76742
|
|
TLR4
|
toll-like receptor 4
|
-3.51379
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.42747
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.33771
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.235
|
|
SNX11
|
sorting nexin 11
|
-3.0817
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.07431
|
|
HMG20B
|
high mobility group 20B
|
-3.02463
|
|
CAB39
|
calcium binding protein 39
|
-2.81644
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.75064
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.68261
|
|
CSK
|
c-src tyrosine kinase
|
-2.54043
|
|
RAB23
|
RAB23, member RAS oncogene family
|
-2.46732
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.25421
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.01958
|
