| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | glutaraldehyde 38.8 um perturbation at 3 h in HEPG2 (Carcinogenome) |
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71 genes differentially expressed following the CRCGN014_HEPG2_3H:N08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 6.54419 |
| EGR1 | early growth response 1 | 6.50269 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 5.23352 |
| ALDOC | aldolase C, fructose-bisphosphate | 4.307 |
| JUN | jun proto-oncogene | 4.25657 |
| HSPA1A | heat shock 70kDa protein 1A | 3.89291 |
| MYLK | myosin light chain kinase | 3.66584 |
| CCNF | cyclin F | 3.36832 |
| ZFP36 | ZFP36 ring finger protein | 3.3112 |
| TRIM13 | tripartite motif containing 13 | 3.08202 |
| JMJD6 | jumonji domain containing 6 | 3.07789 |
| STK10 | serine/threonine kinase 10 | 3.03948 |
| EPN2 | epsin 2 | 2.96432 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | 2.89425 |
| CCP110 | centriolar coiled coil protein 110kDa | 2.73986 |
| CEP57 | centrosomal protein 57kDa | 2.66113 |
| DDIT4 | DNA-damage-inducible transcript 4 | 2.64011 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 2.62257 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 2.60447 |
| H2BC12 | H2B clustered histone 12 | 2.5965 |
| MAP7 | microtubule-associated protein 7 | 2.53212 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.44175 |
| BAMBI | BMP and activin membrane-bound inhibitor | 2.40793 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 2.40566 |
| ZW10 | zw10 kinetochore protein | 2.40375 |
| FOSL1 | FOS-like antigen 1 | 2.35032 |
| IER2 | immediate early response 2 | 2.34502 |
| HMOX1 | heme oxygenase 1 | 2.31762 |
| CYCS | cytochrome c, somatic | 2.3087 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.27852 |
| NKAPD1 | NKAP domain containing 1 | 2.27295 |
| SMC3 | structural maintenance of chromosomes 3 | 2.23457 |
| HYOU1 | hypoxia up-regulated 1 | 2.16713 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | 2.12333 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 | 2.09801 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.08103 |
| THUMPD2 | THUMP domain containing 2 | 2.05386 |
| DIXDC1 | DIX domain containing 1 | 2.04528 |
| TOR1A | torsin family 1, member A (torsin A) | 2.01754 |
| EXOSC4 | exosome component 4 | 2.01322 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -9.84254 |
| LDHD | lactate dehydrogenase D | -7.01889 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.49381 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -5.61006 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -4.69584 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.63883 |
| SLC35F2 | solute carrier family 35, member F2 | -4.60473 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -4.34004 |
| PCNA | proliferating cell nuclear antigen | -3.98308 |
| CCNB1 | cyclin B1 | -3.97902 |
| TRIB3 | tribbles pseudokinase 3 | -3.31502 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -3.28291 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -3.27426 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.25132 |
| DERA | deoxyribose-phosphate aldolase (putative) | -3.2231 |
| VAT1 | vesicle amine transport 1 | -3.04681 |
| PEG10 | paternally expressed 10 | -2.76538 |
| ADAM10 | ADAM metallopeptidase domain 10 | -2.74335 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.53703 |
| CD320 | CD320 molecule | -2.51218 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -2.3855 |
| CGB8 | chorionic gonadotropin, beta polypeptide 8 | -2.37645 |
| TBPL1 | TBP-like 1 | -2.36085 |
| BIRC2 | baculoviral IAP repeat containing 2 | -2.25025 |
| TXNDC9 | thioredoxin domain containing 9 | -2.16971 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.1198 |
| PDCD6 | programmed cell death 6 | -2.06666 |
| TLCD3A | TLC domain containing 3A | -2.03757 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -2.03475 |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 | -2.0144 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -2.00778 |