CRCGN014_HEPG2_3H:N13 Gene Set
Genes
36 genes differentially expressed following the CRCGN014_HEPG2_3H:N13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
5.27181
|
|
UBQLN2
|
ubiquilin 2
|
4.82575
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
4.57845
|
|
NOTCH1
|
notch 1
|
3.92917
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.64526
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.43042
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.31497
|
|
SFTPB
|
surfactant protein B
|
3.15529
|
|
CHN1
|
chimerin 1
|
2.69085
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.49498
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.47563
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.43804
|
|
SATB1
|
SATB homeobox 1
|
2.26042
|
|
MRPL12
|
mitochondrial ribosomal protein L12
|
2.17027
|
|
ZBTB18
|
zinc finger and BTB domain containing 18
|
2.16661
|
|
BCL7B
|
B-cell CLL/lymphoma 7B
|
2.14275
|
|
KMT5B
|
lysine methyltransferase 5B
|
2.11839
|
|
SIRT3
|
sirtuin 3
|
2.10371
|
|
LOC128966622
|
putative protein N-methyltransferase FAM86B2
|
2.09798
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-9.04154
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.73986
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.95261
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.79784
|
|
TSPAN4
|
tetraspanin 4
|
-4.68334
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-4.59062
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.38668
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.336
|
|
GNAS
|
GNAS complex locus
|
-3.84423
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.55789
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.81962
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.81339
|
|
WDR7
|
WD repeat domain 7
|
-2.66293
|
|
WASHC4
|
WASH complex subunit 4
|
-2.36821
|
|
CHEK1
|
checkpoint kinase 1
|
-2.32158
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.13943
|
|
TNFSF9
|
tumor necrosis factor (ligand) superfamily, member 9
|
-2.03873
|