| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | curcumin 20.63 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
100 genes differentially expressed following the CRCGN014_HEPG2_3H:N15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | 7.64225 |
| CHMP6 | charged multivesicular body protein 6 | 6.66493 |
| AXIN1 | axin 1 | 4.92145 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.40962 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 4.24833 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.02003 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.7097 |
| STK10 | serine/threonine kinase 10 | 3.36497 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.14244 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.13925 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 3.07024 |
| EPHB2 | EPH receptor B2 | 3.01531 |
| EGR1 | early growth response 1 | 2.95749 |
| RPL3L | ribosomal protein L3-like | 2.78141 |
| HSPA1B | heat shock 70kDa protein 1B | 2.65894 |
| TESK1 | testis-specific kinase 1 | 2.59813 |
| CHN1 | chimerin 1 | 2.56925 |
| GUCY2D | guanylate cyclase 2D, membrane (retina-specific) | 2.5478 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 | 2.49241 |
| H2BC12 | H2B clustered histone 12 | 2.44561 |
| H2AB2 | H2A.B variant histone 2 | 2.44507 |
| CORO1A | coronin, actin binding protein, 1A | 2.43259 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.4108 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.41002 |
| HPCAL1 | hippocalcin-like 1 | 2.38761 |
| RETN | resistin | 2.37582 |
| PYGM | phosphorylase, glycogen, muscle | 2.27887 |
| PBK | PDZ binding kinase | 2.27238 |
| BAG3 | BCL2-associated athanogene 3 | 2.26972 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 2.26293 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | 2.25717 |
| NTHL1 | nth endonuclease III-like 1 (E. coli) | 2.2247 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | 2.21086 |
| FGF21 | fibroblast growth factor 21 | 2.20549 |
| RGS16 | regulator of G-protein signaling 16 | 2.1872 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.1798 |
| TWIST1 | twist family bHLH transcription factor 1 | 2.16416 |
| MYLK | myosin light chain kinase | 2.15897 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.12724 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 2.10581 |
| CACNA1S | calcium channel, voltage-dependent, L type, alpha 1S subunit | 2.10314 |
| MAMLD1 | mastermind-like domain containing 1 | 2.08264 |
| HRC | histidine rich calcium binding protein | 2.06134 |
| PTK2B | protein tyrosine kinase 2 beta | 2.04714 |
| CDC45 | cell division cycle 45 | 2.04245 |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 2.03055 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.01713 |
| RNF2 | ring finger protein 2 | 2.01428 |
| TEX11 | testis expressed 11 | 2.01338 |
| LOC124900193 | uncharacterized LOC124900193 | 2.00558 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 | 2.00001 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -6.72601 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -6.44294 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -5.8946 |
| CDC25B | cell division cycle 25B | -5.32155 |
| FASTKD5 | FAST kinase domains 5 | -5.31285 |
| GNAS | GNAS complex locus | -5.02635 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -4.49573 |
| IER3 | immediate early response 3 | -3.87278 |
| VAT1 | vesicle amine transport 1 | -3.86471 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.70451 |
| CDC20 | cell division cycle 20 | -3.65488 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -3.64036 |
| BLCAP | bladder cancer associated protein | -3.63858 |
| PCNA | proliferating cell nuclear antigen | -3.5419 |
| CCNB2 | cyclin B2 | -3.45969 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -3.34622 |
| TLR4 | toll-like receptor 4 | -3.2563 |
| MAT2A | methionine adenosyltransferase II, alpha | -3.23932 |
| HEATR1 | HEAT repeat containing 1 | -3.23761 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | -3.06399 |
| GOLT1B | golgi transport 1B | -3.02132 |
| CIRBP | cold inducible RNA binding protein | -2.99211 |
| SCAND1 | SCAN domain containing 1 | -2.98491 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -2.88284 |
| UBE3C | ubiquitin protein ligase E3C | -2.86162 |
| KLHL21 | kelch-like family member 21 | -2.7628 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -2.7393 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.68525 |
| UTP3 | UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) | -2.5331 |
| SNX11 | sorting nexin 11 | -2.52115 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.50188 |
| SCAF8 | SR-related CTD-associated factor 8 | -2.43275 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -2.42285 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -2.37496 |
| PTBP1 | polypyrimidine tract binding protein 1 | -2.23105 |
| ZBTB24 | zinc finger and BTB domain containing 24 | -2.21803 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -2.2118 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | -2.2055 |
| TXNRD1 | thioredoxin reductase 1 | -2.2055 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.19291 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -2.18879 |
| TXLNA | taxilin alpha | -2.15617 |
| SMC4 | structural maintenance of chromosomes 4 | -2.06488 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.05343 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -2.04053 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.0297 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.01299 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.01216 |
| SPRR3 | small proline-rich protein 3 | -2.00609 |
