CRCGN014_HEPG2_3H:N18 Gene Set
Genes
59 genes differentially expressed following the CRCGN014_HEPG2_3H:N18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
7.68221
|
|
E2F2
|
E2F transcription factor 2
|
5.38393
|
|
HYOU1
|
hypoxia up-regulated 1
|
4.51847
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.37952
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.3545
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
4.16311
|
|
MYLK
|
myosin light chain kinase
|
4.06972
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.86048
|
|
GATA3
|
GATA binding protein 3
|
3.81737
|
|
HEBP1
|
heme binding protein 1
|
3.80535
|
|
CEP57
|
centrosomal protein 57kDa
|
3.73953
|
|
SKIC8
|
SKI8 subunit of superkiller complex
|
3.63651
|
|
NOTCH1
|
notch 1
|
3.49979
|
|
TXNL4B
|
thioredoxin-like 4B
|
3.3001
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
3.08744
|
|
MAP7
|
microtubule-associated protein 7
|
2.9747
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.79336
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.62379
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.59896
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.59636
|
|
TBP
|
TATA box binding protein
|
2.5166
|
|
CSK
|
c-src tyrosine kinase
|
2.40162
|
|
AGPAT1
|
1-acylglycerol-3-phosphate O-acyltransferase 1
|
2.30539
|
|
TMEM51
|
transmembrane protein 51
|
2.29914
|
|
GID4
|
GID complex subunit 4
|
2.19377
|
|
KIF14
|
kinesin family member 14
|
2.18551
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.1697
|
|
FOXJ3
|
forkhead box J3
|
2.14049
|
|
GATA2
|
GATA binding protein 2
|
2.13375
|
|
RAC2
|
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
|
2.06523
|
|
KIT
|
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
|
2.03707
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.02613
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-7.77866
|
|
DNM1L
|
dynamin 1-like
|
-5.65565
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.6124
|
|
LDHD
|
lactate dehydrogenase D
|
-5.01069
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.0
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-4.93856
|
|
NUP93
|
nucleoporin 93kDa
|
-4.8697
|
|
CDC20
|
cell division cycle 20
|
-4.76058
|
|
PEG10
|
paternally expressed 10
|
-4.03732
|
|
CPSF4
|
cleavage and polyadenylation specific factor 4, 30kDa
|
-4.00945
|
|
SNX11
|
sorting nexin 11
|
-3.76352
|
|
CDC25B
|
cell division cycle 25B
|
-3.7326
|
|
TLR4
|
toll-like receptor 4
|
-3.67421
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.58384
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
-3.47088
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.95168
|
|
TRANK1
|
tetratricopeptide repeat and ankyrin repeat containing 1
|
-2.78986
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-2.76511
|
|
NECTIN4
|
nectin cell adhesion molecule 4
|
-2.74961
|
|
CCNB1
|
cyclin B1
|
-2.73466
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.42474
|
|
DYNC1LI1
|
dynein, cytoplasmic 1, light intermediate chain 1
|
-2.40784
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.29976
|
|
BICD1
|
bicaudal D homolog 1 (Drosophila)
|
-2.13099
|
|
KCNK5
|
potassium channel, two pore domain subfamily K, member 5
|
-2.12143
|
|
KDM3B
|
lysine (K)-specific demethylase 3B
|
-2.0827
|
|
TCTN1
|
tectonic family member 1
|
-2.05731
|
