CRCGN014_HEPG2_3H:N19 Gene Set
Genes
42 genes differentially expressed following the CRCGN014_HEPG2_3H:N19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
5.79274
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.52041
|
|
UBQLN2
|
ubiquilin 2
|
4.19268
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.1591
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.66534
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.52873
|
|
HOXA10
|
homeobox A10
|
3.51554
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.27939
|
|
NOTCH1
|
notch 1
|
2.87169
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.72248
|
|
NENF
|
neudesin neurotrophic factor
|
2.60259
|
|
CHEK2
|
checkpoint kinase 2
|
2.41042
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.34632
|
|
AXIN1
|
axin 1
|
2.322
|
|
STAM
|
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
|
2.258
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
2.24233
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.2416
|
|
STIMATE
|
STIM activating enhancer
|
2.23575
|
|
MKNK1
|
MAP kinase interacting serine/threonine kinase 1
|
2.20626
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.16127
|
|
KAT6A
|
K(lysine) acetyltransferase 6A
|
2.13725
|
|
TWF2
|
twinfilin actin binding protein 2
|
2.13073
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.04126
|
|
CAPN1
|
calpain 1, (mu/I) large subunit
|
2.03375
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.02152
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-9.88862
|
|
ZNF586
|
zinc finger protein 586
|
-9.29388
|
|
TLR4
|
toll-like receptor 4
|
-5.77738
|
|
LDHD
|
lactate dehydrogenase D
|
-4.10155
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
-2.90597
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
-2.87683
|
|
NVL
|
nuclear VCP-like
|
-2.84432
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.56124
|
|
WDR7
|
WD repeat domain 7
|
-2.29087
|
|
GALNT10
|
polypeptide N-acetylgalactosaminyltransferase 10
|
-2.2476
|
|
ZNF134
|
zinc finger protein 134
|
-2.24386
|
|
SNX11
|
sorting nexin 11
|
-2.21656
|
|
CD58
|
CD58 molecule
|
-2.19118
|
|
ZNF268
|
zinc finger protein 268
|
-2.09089
|
|
ZNF211
|
zinc finger protein 211
|
-2.07708
|
|
MTA1
|
metastasis associated 1
|
-2.07506
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.01857
|
