CRCGN014_HEPG2_3H:N20 Gene Set
Genes
34 genes differentially expressed following the CRCGN014_HEPG2_3H:N20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
5.35521
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
4.97764
|
|
CYCS
|
cytochrome c, somatic
|
4.85571
|
|
GPATCH8
|
G patch domain containing 8
|
4.39802
|
|
MEF2C
|
myocyte enhancer factor 2C
|
4.34937
|
|
CSK
|
c-src tyrosine kinase
|
4.19613
|
|
MEST
|
mesoderm specific transcript
|
4.04368
|
|
MAP7
|
microtubule-associated protein 7
|
3.67423
|
|
EPHA3
|
EPH receptor A3
|
3.36006
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.21961
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.04994
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.88829
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.58842
|
|
CTSL
|
cathepsin L
|
2.3945
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.36578
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
2.09118
|
|
TSPAN6
|
tetraspanin 6
|
2.03433
|
|
SKIC8
|
SKI8 subunit of superkiller complex
|
2.02133
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-7.39119
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-6.83581
|
|
LDHD
|
lactate dehydrogenase D
|
-6.51804
|
|
CCNB2
|
cyclin B2
|
-4.81468
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.75709
|
|
GNAS
|
GNAS complex locus
|
-3.72797
|
|
VAT1
|
vesicle amine transport 1
|
-3.59031
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.57854
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.23356
|
|
SNX11
|
sorting nexin 11
|
-3.22119
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.21692
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.96406
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.91289
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
-2.59714
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-2.48559
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-2.17389
|
