| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dibenzo-p-dioxin 39.6 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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74 genes differentially expressed following the CRCGN014_HEPG2_3H:N22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPP38 | ribonuclease P/MRP 38kDa subunit | 8.82515 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.4676 |
| EAPP | E2F-associated phosphoprotein | 5.1537 |
| CSK | c-src tyrosine kinase | 4.91945 |
| EPHB2 | EPH receptor B2 | 4.72054 |
| MAP7 | microtubule-associated protein 7 | 4.69895 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.666 |
| MEST | mesoderm specific transcript | 4.62455 |
| UBQLN2 | ubiquilin 2 | 4.539 |
| STIMATE | STIM activating enhancer | 4.40005 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.1937 |
| CNPY3 | canopy FGF signaling regulator 3 | 4.1155 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.77402 |
| ZNF589 | zinc finger protein 589 | 3.42738 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.07233 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.0553 |
| KIFBP | kinesin family binding protein | 3.0135 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 2.96895 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 2.82995 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.48813 |
| JADE2 | jade family PHD finger 2 | 2.43458 |
| IER3 | immediate early response 3 | 2.3644 |
| EVL | Enah/Vasp-like | 2.35575 |
| PFKP | phosphofructokinase, platelet | 2.3494 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 2.2992 |
| FOXJ3 | forkhead box J3 | 2.27953 |
| KIF14 | kinesin family member 14 | 2.2645 |
| VIL1 | villin 1 | 2.231 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | 2.2126 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.15455 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) | 2.1492 |
| CA9 | carbonic anhydrase IX | 2.1385 |
| COA4 | cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) | 2.1256 |
| GPKOW | G patch domain and KOW motifs | 2.0554 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 2.05225 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 2.03222 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -8.48175 |
| VAT1 | vesicle amine transport 1 | -5.56315 |
| ZNF586 | zinc finger protein 586 | -4.80645 |
| LDHD | lactate dehydrogenase D | -4.7773 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -4.62817 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -4.6161 |
| TXNDC9 | thioredoxin domain containing 9 | -3.85283 |
| GNAS | GNAS complex locus | -3.54542 |
| CCNH | cyclin H | -3.51715 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.41237 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -3.10665 |
| TLCD3A | TLC domain containing 3A | -3.07045 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -3.04353 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.8647 |
| ARL8B | ADP-ribosylation factor-like 8B | -2.73235 |
| CD320 | CD320 molecule | -2.72145 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.66577 |
| DPY19L4 | dpy-19-like 4 (C. elegans) | -2.56195 |
| WASHC4 | WASH complex subunit 4 | -2.49052 |
| TCHH | trichohyalin | -2.4818 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.47495 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -2.46095 |
| MVP | major vault protein | -2.4076 |
| CLDN10 | claudin 10 | -2.3705 |
| ZNF516 | zinc finger protein 516 | -2.34595 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | -2.2869 |
| TOGARAM1 | TOG array regulator of axonemal microtubules 1 | -2.17225 |
| CADPS2 | Ca++-dependent secretion activator 2 | -2.16165 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -2.16033 |
| TWF2 | twinfilin actin binding protein 2 | -2.12365 |
| TCTN1 | tectonic family member 1 | -2.1055 |
| HDLBP | high density lipoprotein binding protein | -2.104 |
| KIFC3 | kinesin family member C3 | -2.10205 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) | -2.0819 |
| ANKRD28 | ankyrin repeat domain 28 | -2.0636 |
| AMT | aminomethyltransferase | -2.03875 |
| SNX24 | sorting nexin 24 | -2.00305 |
| BBOF1 | basal body orientation factor 1 | -2.00055 |
