CRCGN014_HEPG2_3H:O04 Gene Set
Genes
36 genes differentially expressed following the CRCGN014_HEPG2_3H:O04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
5.013
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.88756
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.82318
|
|
CHN1
|
chimerin 1
|
4.50047
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.88354
|
|
TBP
|
TATA box binding protein
|
3.01552
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.69951
|
|
STIMATE
|
STIM activating enhancer
|
2.60339
|
|
MYLK
|
myosin light chain kinase
|
2.47546
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.45058
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.3279
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.2535
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.18357
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-8.61725
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-6.97809
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-5.02828
|
|
LDHD
|
lactate dehydrogenase D
|
-4.92745
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.64167
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.30511
|
|
GNAS
|
GNAS complex locus
|
-3.84774
|
|
CCNB1
|
cyclin B1
|
-3.76326
|
|
HEATR1
|
HEAT repeat containing 1
|
-3.65013
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.16977
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.12598
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.88749
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
-2.42932
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
-2.39683
|
|
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta
|
-2.17165
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.17078
|
|
CCNB2
|
cyclin B2
|
-2.14016
|
|
UGT8
|
UDP glycosyltransferase 8
|
-2.07042
|
|
EID1
|
EP300 interacting inhibitor of differentiation 1
|
-2.05918
|
|
SPTBN5
|
spectrin, beta, non-erythrocytic 5
|
-2.0577
|
|
RHBDF1
|
rhomboid 5 homolog 1 (Drosophila)
|
-2.04889
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.02939
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.0259
|
