| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | beta-carotene 20.2 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
78 genes differentially expressed following the CRCGN014_HEPG2_3H:O05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDIT4 | DNA-damage-inducible transcript 4 | 10.0 |
| HSPA1A | heat shock 70kDa protein 1A | 10.0 |
| HMOX1 | heme oxygenase 1 | 9.55735 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 6.76386 |
| ABHD4 | abhydrolase domain containing 4 | 6.26577 |
| BAG3 | BCL2-associated athanogene 3 | 5.07292 |
| HSPA1B | heat shock 70kDa protein 1B | 4.64966 |
| LPAR2 | lysophosphatidic acid receptor 2 | 4.29784 |
| TXNRD1 | thioredoxin reductase 1 | 4.07083 |
| TRIB3 | tribbles pseudokinase 3 | 3.46781 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 3.45434 |
| PNKP | polynucleotide kinase 3'-phosphatase | 3.43084 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 3.42121 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.41211 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 3.24497 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.21897 |
| LCN2 | lipocalin 2 | 3.1608 |
| PRR15L | proline rich 15-like | 3.13338 |
| CYCS | cytochrome c, somatic | 3.11448 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.03616 |
| UBQLN2 | ubiquilin 2 | 2.86613 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 2.8371 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.70266 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 2.65571 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.63024 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 2.59058 |
| CHN1 | chimerin 1 | 2.55073 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.51262 |
| FCHO1 | FCH domain only 1 | 2.34188 |
| SKIC8 | SKI8 subunit of superkiller complex | 2.34104 |
| ZNF473 | zinc finger protein 473 | 2.29924 |
| SQSTM1 | sequestosome 1 | 2.28018 |
| ZNF589 | zinc finger protein 589 | 2.27082 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 2.22127 |
| NOSIP | nitric oxide synthase interacting protein | 2.21253 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.20586 |
| SFTPB | surfactant protein B | 2.14291 |
| SATB1 | SATB homeobox 1 | 2.10427 |
| KEAP1 | kelch-like ECH-associated protein 1 | 2.08789 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 2.04892 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.00219 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.00087 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VAT1 | vesicle amine transport 1 | -10.0 |
| LDHD | lactate dehydrogenase D | -6.70026 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.27155 |
| CDC20 | cell division cycle 20 | -4.76138 |
| NGRN | neugrin, neurite outgrowth associated | -4.15369 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.85485 |
| ISOC1 | isochorismatase domain containing 1 | -3.70513 |
| ADI1 | acireductone dioxygenase 1 | -3.61444 |
| TXNDC9 | thioredoxin domain containing 9 | -3.49093 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -3.37425 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.32799 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.28235 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -3.15239 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.09281 |
| CD320 | CD320 molecule | -3.00156 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.95668 |
| IER3 | immediate early response 3 | -2.73152 |
| TLR4 | toll-like receptor 4 | -2.645 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -2.61628 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.57957 |
| SLC35F2 | solute carrier family 35, member F2 | -2.53239 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.51349 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -2.46788 |
| ZNF274 | zinc finger protein 274 | -2.25563 |
| COG2 | component of oligomeric golgi complex 2 | -2.19572 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.1943 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | -2.18582 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.16408 |
| SLC2A4RG | SLC2A4 regulator | -2.14536 |
| ICAM3 | intercellular adhesion molecule 3 | -2.14456 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.10317 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.09329 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -2.0719 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.06151 |
| GALE | UDP-galactose-4-epimerase | -2.04457 |
| CCDC86 | coiled-coil domain containing 86 | -2.03287 |
