CRCGN014_HEPG2_3H:O06 Gene Set
Genes
41 genes differentially expressed following the CRCGN014_HEPG2_3H:O06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
DDIT4
|
DNA-damage-inducible transcript 4
|
9.98191
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
5.64254
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
4.32502
|
|
VGLL4
|
vestigial-like family member 4
|
4.03922
|
|
MTHFD2
|
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
|
3.96949
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.59514
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.59119
|
|
MKNK1
|
MAP kinase interacting serine/threonine kinase 1
|
3.54423
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
3.25973
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.21869
|
|
CYCS
|
cytochrome c, somatic
|
3.20654
|
|
TRIB3
|
tribbles pseudokinase 3
|
3.17898
|
|
AARS1
|
alanyl-tRNA synthetase 1
|
2.83284
|
|
FZD7
|
frizzled class receptor 7
|
2.7011
|
|
EPN2
|
epsin 2
|
2.68484
|
|
MEF2C
|
myocyte enhancer factor 2C
|
2.67173
|
|
STXBP2
|
syntaxin binding protein 2
|
2.62947
|
|
PRR15L
|
proline rich 15-like
|
2.6108
|
|
ZBTB35
|
zinc finger and BTB domain containing 35
|
2.59616
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
2.50474
|
|
TEX10
|
testis expressed 10
|
2.42837
|
|
MOK
|
MOK protein kinase
|
2.30344
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.1344
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.08836
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-6.10457
|
|
GNAS
|
GNAS complex locus
|
-4.86427
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.78359
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.71784
|
|
TLR4
|
toll-like receptor 4
|
-3.47809
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-3.45205
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-3.27032
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.19667
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.13403
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.78978
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.74891
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.56613
|
|
TBC1D31
|
TBC1 domain family, member 31
|
-2.50208
|
|
CDC25B
|
cell division cycle 25B
|
-2.44412
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.33795
|
|
GET1
|
guided entry of tail-anchored proteins factor 1
|
-2.19078
|
|
SCAND1
|
SCAN domain containing 1
|
-2.11551
|
