CRCGN014_HEPG2_3H:O13 Gene Set
Genes
48 genes differentially expressed following the CRCGN014_HEPG2_3H:O13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
10.0
|
|
MSRA
|
methionine sulfoxide reductase A
|
4.99627
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
4.74403
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.67257
|
|
CHN1
|
chimerin 1
|
4.00131
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.98426
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.90083
|
|
MAP7
|
microtubule-associated protein 7
|
3.64584
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.46304
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.3416
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.30178
|
|
CEP57
|
centrosomal protein 57kDa
|
3.1572
|
|
ANKRD10
|
ankyrin repeat domain 10
|
2.94899
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.94898
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
2.91768
|
|
KIF14
|
kinesin family member 14
|
2.79984
|
|
STX1A
|
syntaxin 1A (brain)
|
2.58238
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.582
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
2.45871
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.30115
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.28253
|
|
CCNA1
|
cyclin A1
|
2.25513
|
|
CCNF
|
cyclin F
|
2.22792
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.1305
|
|
DNA2
|
DNA replication helicase/nuclease 2
|
2.1164
|
|
SACM1L
|
SAC1 suppressor of actin mutations 1-like (yeast)
|
2.1107
|
|
SYNGAP1
|
synaptic Ras GTPase activating protein 1
|
2.11002
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.05702
|
|
PRKCH
|
protein kinase C, eta
|
2.03968
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-6.66398
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.53948
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
-4.91315
|
|
LDHD
|
lactate dehydrogenase D
|
-4.73808
|
|
CDC20
|
cell division cycle 20
|
-4.66813
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-4.32739
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.17502
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.94835
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-3.83969
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
-3.11117
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.9685
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.90728
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.82155
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.80574
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.6199
|
|
MCOLN3
|
mucolipin 3
|
-2.20613
|
|
HMOX1
|
heme oxygenase 1
|
-2.20058
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.18183
|
|
VPREB3
|
pre-B lymphocyte 3
|
-2.14446
|
