CRCGN014_HEPG2_3H:O14 Gene Set
Genes
49 genes differentially expressed following the CRCGN014_HEPG2_3H:O14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
6.27898
|
|
CBR3
|
carbonyl reductase 3
|
4.4299
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
4.38533
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
3.85359
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.79164
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
3.72107
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
3.68851
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
3.64044
|
|
EPHA3
|
EPH receptor A3
|
3.49843
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.46725
|
|
HOXA10
|
homeobox A10
|
3.17309
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.16112
|
|
BLMH
|
bleomycin hydrolase
|
2.84757
|
|
GATA3
|
GATA binding protein 3
|
2.70565
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.44342
|
|
SATB1
|
SATB homeobox 1
|
2.3543
|
|
PRKAG1
|
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
|
2.25491
|
|
WRAP73
|
WD repeat containing, antisense to TP73
|
2.25065
|
|
EXOSC4
|
exosome component 4
|
2.23605
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.22014
|
|
TRIM9
|
tripartite motif containing 9
|
2.2115
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.16558
|
|
UBE2NL
|
ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
|
2.12646
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.03244
|
|
HBG1
|
hemoglobin, gamma A
|
2.02545
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.01462
|
|
LDHD
|
lactate dehydrogenase D
|
-5.48372
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.4733
|
|
ZNF586
|
zinc finger protein 586
|
-4.22761
|
|
CD320
|
CD320 molecule
|
-3.98448
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.89581
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.83238
|
|
CCNB2
|
cyclin B2
|
-3.5732
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.73583
|
|
PDIA2
|
protein disulfide isomerase family A, member 2
|
-2.72339
|
|
IPO13
|
importin 13
|
-2.70238
|
|
GNAS
|
GNAS complex locus
|
-2.60109
|
|
EGF
|
epidermal growth factor
|
-2.58344
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.4489
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-2.36984
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.36766
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.33675
|
|
CLDN4
|
claudin 4
|
-2.21994
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.08804
|
|
DOC2A
|
double C2-like domains, alpha
|
-2.03969
|
|
GFRA3
|
GDNF family receptor alpha 3
|
-2.02486
|
|
ECHDC3
|
enoyl CoA hydratase domain containing 3
|
-2.02013
|
|
TOR1A
|
torsin family 1, member A (torsin A)
|
-2.01794
|
|
PLAU
|
plasminogen activator, urokinase
|
-2.01251
|
