CRCGN014_HEPG2_3H:O16 Gene Set
Genes
48 genes differentially expressed following the CRCGN014_HEPG2_3H:O16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
4.75451
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.59752
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.51917
|
|
EPHB2
|
EPH receptor B2
|
4.36617
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.19372
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.67688
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.64308
|
|
HOXA10
|
homeobox A10
|
3.54357
|
|
CRTAP
|
cartilage associated protein
|
3.27833
|
|
RAB31
|
RAB31, member RAS oncogene family
|
3.03086
|
|
UBR7
|
ubiquitin protein ligase E3 component n-recognin 7 (putative)
|
2.94999
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
2.78054
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.65432
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.57003
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.51829
|
|
HPS4
|
Hermansky-Pudlak syndrome 4
|
2.48266
|
|
CRYGC
|
crystallin, gamma C
|
2.22651
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.2222
|
|
EFEMP2
|
EGF containing fibulin-like extracellular matrix protein 2
|
2.12987
|
|
ILK
|
integrin-linked kinase
|
2.08078
|
|
CCL24
|
chemokine (C-C motif) ligand 24
|
2.07271
|
|
B4GAT1
|
beta-1,4-glucuronyltransferase 1
|
2.066
|
|
RAG1
|
recombination activating gene 1
|
2.03243
|
|
SMAD7
|
SMAD family member 7
|
2.01898
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-9.36689
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-5.03355
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-5.03059
|
|
PLK1
|
polo-like kinase 1
|
-4.55766
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.51756
|
|
LDHD
|
lactate dehydrogenase D
|
-4.09802
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.8583
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.84175
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.7856
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.64985
|
|
CSK
|
c-src tyrosine kinase
|
-3.34298
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-3.01732
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.70002
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.56724
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.56647
|
|
RIOK2
|
RIO kinase 2
|
-2.26381
|
|
KITLG
|
KIT ligand
|
-2.26224
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.23556
|
|
LOC128125822
|
uncharacterized LOC128125822
|
-2.14713
|
|
LOC107986346
|
mitochondrial import receptor subunit TOM7 homolog
|
-2.14441
|
|
TBC1D31
|
TBC1 domain family, member 31
|
-2.1415
|
|
ZDHHC4
|
zinc finger, DHHC-type containing 4
|
-2.12356
|
|
SLC9A3R1
|
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
|
-2.06223
|
|
RBM15
|
RNA binding motif protein 15
|
-2.04571
|
