CRCGN014_HEPG2_3H:O17 Gene Set
Genes
42 genes differentially expressed following the CRCGN014_HEPG2_3H:O17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
7.64122
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
6.59987
|
|
MAP7
|
microtubule-associated protein 7
|
5.64107
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.44367
|
|
STK10
|
serine/threonine kinase 10
|
4.05157
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.03013
|
|
STAP2
|
signal transducing adaptor family member 2
|
3.8687
|
|
NOTCH1
|
notch 1
|
3.73979
|
|
RPL39L
|
ribosomal protein L39-like
|
3.48533
|
|
E2F2
|
E2F transcription factor 2
|
3.44556
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
3.31083
|
|
EPHA3
|
EPH receptor A3
|
3.10878
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.04182
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.99803
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.8827
|
|
PRKCH
|
protein kinase C, eta
|
2.8627
|
|
MEST
|
mesoderm specific transcript
|
2.38119
|
|
SAA2
|
serum amyloid A2
|
2.33129
|
|
RALGDS
|
ral guanine nucleotide dissociation stimulator
|
2.25416
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.12905
|
|
CD247
|
CD247 molecule
|
2.10985
|
|
SIRT3
|
sirtuin 3
|
2.03492
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.81797
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.64153
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.68971
|
|
NVL
|
nuclear VCP-like
|
-3.29217
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-3.20045
|
|
DNM1L
|
dynamin 1-like
|
-2.95739
|
|
GNAS
|
GNAS complex locus
|
-2.788
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.76273
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.69782
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.66982
|
|
VAT1
|
vesicle amine transport 1
|
-2.30208
|
|
DEGS1
|
delta(4)-desaturase, sphingolipid 1
|
-2.29726
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.28343
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.20302
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
-2.1361
|
|
TBC1D31
|
TBC1 domain family, member 31
|
-2.11097
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.05976
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.04132
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.02635
|
|
APEH
|
acylaminoacyl-peptide hydrolase
|
-2.00501
|
